Stephan W. Münch

ORCID: 0000-0001-9830-080X
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About
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Research Areas
  • X-ray Diffraction in Crystallography
  • Photosynthetic Processes and Mechanisms
  • Crystallization and Solubility Studies
  • Monoclonal and Polyclonal Antibodies Research
  • Chemical Synthesis and Analysis
  • Coenzyme Q10 studies and effects
  • Organoboron and organosilicon chemistry
  • Mass Spectrometry Techniques and Applications
  • Ferrocene Chemistry and Applications
  • Lipid Membrane Structure and Behavior
  • Cellular transport and secretion
  • Plant Stress Responses and Tolerance
  • Advanced Biosensing Techniques and Applications
  • Analytical Chemistry and Chromatography
  • Luminescence and Fluorescent Materials
  • Insect-Plant Interactions and Control
  • Plant Molecular Biology Research
  • Organic Light-Emitting Diodes Research
  • Advanced biosensing and bioanalysis techniques

Karlsruhe Institute of Technology
2016-2021

Abstract Ten borylated bipyridines (BOBIPYs) have been synthesized and selected structural modifications made that allow useful structure–optical property relationships to be gathered. These systems further investigated using DFT calculations spectroscopic measurements, showing blue green fluorescence with quantum yields up 41 %. They full mapping of the structure determine where functionalities can implemented, tune optical properties or incorporate linking groups. The best derivative was...

10.1002/chem.201601915 article EN Chemistry - A European Journal 2016-07-28

Here, the combinatorial synthesis of molecule arrays via a laser-assisted process is reported. Laser-transferred polymer nanolayers with embedded monomers, activators, or bases can be reliably stacked on top each other, spot-by-spot, to synthesize arrays. These various chemicals in nanometer-thin layers are mixed by heat solvent vapor, inducing coupling reactions. As an example, peptoid density 10 000 spots per cm2 sub-monomer monomer method generated. Moreover, successful reactions...

10.1002/marc.201800533 article EN Macromolecular Rapid Communications 2018-12-21

Salinity is a serious challenge to global agriculture and threatens human food security. Plant cells can respond salt stress either by activation of adaptive responses, or programmed cell death. The mechanisms deciding the respective response are far from understood, but seem depend on degree, which mitochondria maintain oxidative homeostasis. Using plant PeptoQ, Trojan Peptoid, as vehicle, it possible transport coenzyme Q10 (CoQ10) derivative into mitochondria. We show that salinity in...

10.1038/s41598-020-68491-4 article EN cc-by Scientific Reports 2020-07-14

Controlled delivery of molecules interfering specifically with target activities in a cell interest can be powerful tool for experimental manipulation, because it administered at defined time point and does not require genetic transformation, which some systems is difficult consuming. Peptides as versatile tools that tailored binding numerous partners, are special interest. However, their passage through membranes, intracellular targeting, sensitivity to proteases limiting. The use peptoids,...

10.1038/s41598-019-46182-z article EN cc-by Scientific Reports 2019-07-08

Abstract Microarrays are an important tool in modern research that allow the rapid screening of many different interactions simultaneously. Peptide arrays, which bear peptides arranged separate spots, permit high‐throughput to investigate linear and cyclic binding sites. To study conformational or discontinuous sites, protein arrays major choice. However, tremendous costs for generation high‐density high purity restrict progress research. Therefore, peptide‐based can mimic assembled peptide...

10.1002/smtd.201700205 article EN Small Methods 2017-12-06
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