We experience our body as a 3D, volumetric object in the world. Measures of conscious image, contrast, have investigated perception size along one or two dimensions at time. There is, thus, discrepancy between existing methods for measuring image and subjective having 3D body. Here we assessed sample healthy adults terms its 1D length volume. Participants were randomly assigned to groups using different units (other part non-body object). They estimated how many would fit perceived segments...

Psychophysical experiments have demonstrated large and highly systematic perceptual distortions of tactile space. Such a space can be referred to our experience the spatial organisation objects, at representational level, through touch, in analogy with familiar concept visual We investigated neural basis by analysing activity patterns induced stimulation nine points on 3 × square grid hand dorsum using functional magnetic resonance imaging. used searchlight approach within pre-defined...

Vision of the body, even when non-informative about stimulation, affects somatosensory processing. We investigated whether seeing body also modulates autonomic control in periphery by measuring skin temperature while manipulating vision. Using a mirror box, was measured from left hand dorsum participants: (i) had illusion their hand, (ii) an object at same location or (iii) looked directly contralateral right hand. Skin increased participants that but not other two view conditions. In...

In this study, we aimed to relate the findings from two predominantly separate streams of literature, one reporting on localisation single touches skin, and other distance perception dual touches. Participants were touched with points, delivered either simultaneously or separated by a short delay various locations their left hand dorsum. They then indicated size-matched silhouette perceived tactile stimuli. We quantified deviations between actual stimulus grid corresponding perceptual map...

Sensory perception, motor control, and cognition necessitate reliable timing in the range of milliseconds to seconds, which implies existence a highly accurate system. Yet, partly owing fact that temporal processing is modulated by contextual factors, perceived time not isomorphic physical time. Temporal estimates exhibit regression mean an interval distribution (

Abstract Recent theoretical work embedded within the predictive processing framework has proposed that neurocognitive and therapeutic effects of psychedelics are driven by modulation priors (Carhart-Harris & Friston, 2019). We conducted pre-registered re-analyses previous research (Yanakieva et al., 2019) to examine whether microdoses lysergic acid diethylamide (LSD) alleviate temporal reproduction bias introduced priors, as predicted this framework. In a between-groups design,...

Timing behaviour and the perception of time are fundamental to cognitive emotional processes in humans. In non-human model organisms, neuromodulator dopamine has been associated with variations timing behaviour, but connection between levels human experience not directly assessed. Here, we report how striatum, measured sub-second temporal resolution during awake deep brain stimulation surgery, relate participants' perceptual judgements intervals. Fast, phasic, dopaminergic signals were...

Abstract The perception of time is characterized by pronounced variability across individuals, with implications for a diverse array psychological functions. neurocognitive sources this are poorly understood, but accumulating evidence suggests role inter-individual differences in striatal dopamine levels. Here we present pre-registered study that tested the predictions spontaneous eyeblink rates, which provide proxy measure availability, would be associated aberrant interval timing (lower...

State-dependent network models of sub-second interval timing propose that duration is encoded in states neuronal populations need to reset prior a novel operation maintain optimal performance. Previous research has shown the approximate boundary this can be inferred by varying inter-stimulus between two to-be-timed intervals. However, estimated broad (250-500 ms) and remains under-specified with implications for characteristics state-dependent dynamics sub-serving timing. Here, we probed...

Decreasing dopaminergic function is at the core of Parkinson's disease (PD) motor symptoms and changes in action are associated with many comorbid non-motor PD. Notably, signaling striatum has been shown to play a critical role perception time. We hypothesize that patients PD perceive time differently accordance their specific clinical state. This means individual differences may be reflected timing behavior. To test this hypothesis, we recruited compared patients' state ability judge...

Abstract Psychophysical experiments have demonstrated large and highly systematic perceptual distortions of tactile space. We investigated the neural basis space by analyzing activity patterns induced stimulation nine points on a 3 × square grid hand dorsum using functional magnetic resonance (fMRI). used searchlight approach within pre-defined regions interests (ROIs) to compute pairwise Euclidean distances between elicited stimulation. Then, we multidimensional scaling (MDS) reconstruct at...

The skin of the forearm is, in one sense, a flat 2-dimensional (2D) sheet, but another sense approximately cylindrical, mirroring 3-dimensional (3D) volumetric shape arm. role frames reference based on as 2D sheet versus musculoskeletal structure arm remains unclear. When we rotate from pronated to supinated posture, its surface is displaced. Thus, marked location will slide with across underlying flesh, and touch perceived at this should follow displacement if it localized within skin-based...

Bayesian optional stopping refers to the practice of repeatedly performing a statistical analysis on dataset as new data are collected until pre-specified evidence criterion is reached. This procedure becoming increasingly common owing in part its efficacy optimizing collection. Discussions this date have been restricted issues and omitted consideration any methodological implications procedure. Here we highlight experimenter awareness current state during collection (experimenter unmasking)...

Abstract Dopaminergic signaling in the striatum has been shown to play a critical role perception of time. Decreasing striatal dopamine efficacy is at core Parkinson’s disease (PD) motor symptoms and changes dopaminergic action have associated with many comorbid non-motor PD. We hypothesize that patients PD perceive time differently accordance their specific clinical state. recruited compared individual differences patients’ features ability judge millisecond second intervals (500ms-1100ms)...

Abstract The perception of time is characterized by pronounced variability across individuals, with implications for a diverse array psychological functions. neurocognitive sources this are poorly understood but accumulating evidence suggests role inter-individual differences in striatal dopamine levels. Here we present pre-registered study that tested the predictions spontaneous eye blink rates, which provide proxy measure availability, would be associated aberrant interval timing (lower...

Sensory perception, motor control, and cognition necessitate reliable timing in the range of milliseconds to seconds, which implies existence a highly accurate system. Yet, partly owing fact that temporal processing is modulated by contextual factors, perceived time not isomorphic physical time. Temporal estimates exhibit regression mean an interval distribution (global context) are also affected preceding trials (local context). Recent Bayesian models have provided important insights...

One of the ongoing controversies in interval timing concerns whether human time perception relies on multiple distinct mechanisms. This debate centres around subsecond and suprasecond may be attributed to a single semi-uniform mechanism or separate interacting Whereas past studies offer valuable insights, this study overcomes previous limitations by adopting convergent statistical approaches design with strong power. We conducted two online experiments involving participants reproducing...