A5087527057- Cardiovascular Conditions and Treatments
- Congenital Heart Disease Studies
- Trypanosoma species research and implications
- Research on Leishmaniasis Studies
- Cardiac Arrhythmias and Treatments
- Mechanical Circulatory Support Devices
- Congenital heart defects research
- Coronary Artery Anomalies
- Cardiac Valve Diseases and Treatments
- Cardiovascular Effects of Exercise
- Insect symbiosis and bacterial influences
- Parasitic Infections and Diagnostics
- Vascular anomalies and interventions
- Atrial Fibrillation Management and Outcomes
- Parasitic Diseases Research and Treatment
- Viral Infections and Immunology Research
- Vector-borne infectious diseases
- Helminth infection and control
- Cardiomyopathy and Myosin Studies
- Cardiovascular and Diving-Related Complications
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Cardiac electrophysiology and arrhythmias
- Hemodynamic Monitoring and Therapy
- Transplantation: Methods and Outcomes
- Bird parasitology and diseases
Texas A&M University
2016-2025
Bristol-Myers Squibb (United States)
2022-2023
Texas College
2022
Loma Linda University
2021
Loma Linda University Medical Center
2021
University Hospitals of Cleveland
2018
University School
2018
Case Western Reserve University
2018
Pankey Institute
2013-2015
Colorado State University
2006-2012
Abstract A nonhydrostatic cloud model is used to examine the thermomechanics of tropical cyclogenesis under realistic meteorological conditions. Observations motivate focus on problem how a midtropospheric cyclonic vortex, frequent by-product mesoscale convective systems during summertime conditions over oceans, may be transformed into surface-concentrated (warm core) depression. As first step, vortex transformation studied in absence vertical wind shear or zonal flow. Within vorticity-rich...
Background Pimobendan is effective in treatment of dogs with congestive heart failure (CHF) secondary to myxomatous mitral valve disease (MMVD). Its effect on before the onset CHF unknown. Hypothesis/Objectives Administration pimobendan (0.4–0.6 mg/kg/d divided doses) increased size preclinical MMVD, not receiving other cardiovascular medications, will delay signs CHF, cardiac‐related death, or euthanasia. Animals 360 client‐owned MMVD left atrial‐to‐aortic ratio ≥1.6, normalized ventricular...
Background Published information regarding survival and long‐term cardiac remodeling after patent ductus arteriosus ( PDA ) closure in dogs is limited. Objectives To report outcome identify prognostic variables with , to risk factors for persistent a minimum of 12 months follow‐up closure. Animals Five hundred twenty client‐owned dogs. Methods Retrospective review medical records 520 . Outcome was determined by contacting owners veterinarians. Dogs ≥ were asked return re‐evaluation. Results...
Changes in clinical variables associated with the administration of pimobendan to dogs preclinical myxomatous mitral valve disease (MMVD) and cardiomegaly have not been described.To investigate effect on relationship between a change heart size time congestive failure (CHF) or cardiac-related death (CRD) MMVD cardiomegaly. To determine whether pimobendan-treated differ from receiving placebo at onset CHF.Three hundred fifty-four cardiomegaly.Prospective, blinded study randomized (ratio 1:1)...
Trypanosoma cruzi naturally infects a broad range of mammalian species and frequently results in the pathology that has been most extensively characterized human Chagas disease. Currently employed treatment regimens fail to achieve parasitological cure T. infection majority cases. In this study, we have extended our previous investigations more effective, higher dose, intermittent administration protocols using FDA-approved drug benznidazole (BNZ), experimentally infected mice dogs nonhuman...
Chylothorax is a devastating disease, and the success rates from either medical or surgical management are less than satisfactory. In some animals with chylothorax, thickening of pericardium occurs that associated chronic irritation induced by chyle. We hypothesized pericardial would lead to increased right‐sided venous pressures abnormal act impede drainage chyle via lymphaticovenous communications after thoracic duct (TD) ligation. also serosanguineous effusions occurred TD ligation could...
Abstract Trypanosoma cruzi infection in dogs can cause heart failure and sudden death with few treatment options available. A litter of 4 living a T endemic area were randomized to prophylaxis nonprophylaxis groups as part study evaluating modified benznidazole dosing regimen administered twice weekly prevent during vector transmission season. The 2 that received remained healthy without or cardiac disease for >2 years. One dog did not receive died unexpectedly acute –induced pancarditis,...
Trypanosoma cruzi , the protozoan parasite and cause of Chagas disease, is widely distributed in many vertebrate triatomine species throughout North, Central, South America. Variations housing quality largely determines human infection risk Americas. However, southern U.S. contains widespread, infected vectors captive domesticated animals with active T. or at high becoming developing disease. There a critical need for better detection intervention strategies, principally focused on Americas,...
Infection with the protozoan parasite Trypanosoma cruzi is generally well-controlled by host immune responses, but appears to be rarely eliminated. The resulting persistent, low-level infection results in cumulative tissue damage greatest impact heart form of chagasic cardiomyopathy. relative success control T. usually averts acute phase death has negative consequence that presence hosts challenging detect unequivocally. Thus, it difficult identify those who are actively infected and, as...
Infection with the protozoan parasite Trypanosoma cruzi is generally well-controlled by host immune responses, but appears to be rarely eliminated. The resulting persistent, low-level infection results in cumulative tissue damage greatest impact heart form of chagasic cardiomyopathy. relative success control T. usually averts acute phase death has negative consequence that presence hosts challenging detect unequivocally. Thus, it difficult identify those who are actively infected and, as...
Chylothorax is a devastating disease, and the success rates from either medical or surgical management are less than satisfactory. In some animals with chylothorax, thickening of pericardium occurs that associated chronic irritation induced by chyle. We hypothesized pericardial would lead to increased right-sided venous pressures abnormal act impede drainage chyle via lymphaticovenous communications after thoracic duct (TD) ligation. also serosanguineous effusions occurred TD ligation could...
Canine Chagas disease, caused by the protozoan parasite Trypanosoma cruzi , is increasingly recognized as a health concern for dogs in USA, and infected may signal geographic regions of risk human disease. Dogs living multi-dog kennel environments (kennels with more than one dog) where triatomine vectors are endemic be at high infection. We monitored cohort 64 T . -infected uninfected across 10 kennels Texas, to characterize changes infection status over year. used robust diagnostic criteria...
To determine the effect of PO administration pimobendan on clinical and echocardiographic variables survival time in cats with heart failure characterized by ventricular systolic dysfunction.Retrospective cohort study.27 client-owned (16 male 11 female) failure, treated (mean ± SD dosage, 0.26 0.08 mg/kg [0.118 0.036 mg/lb], PO, q 12 h).Information medical history, laboratory results, diagnostic imaging findings, treatments received, were obtained from records that received because cardiac...
A 10-week old, intact male, Boxer puppy was referred to the Texas A&M University Veterinary Medical Teaching Hospital (TAMU-VMTH) for emergency evaluation of ascites secondary right-sided heart failure approximately 2 weeks after owners purchased dog from a breeder in south Texas. Clinical signs began days before presentation, and included lethargy, acute inappetence, diarrhea, vomiting that nonresponsive antiemetic therapy. At time, tested negative parvovirus antigen. Abdominal thoracic...
Transarterial ductal occlusion with the Amplatzer vascular plug was first reported in dogs by Hogan et al 2005.Use of is a safe, efficacious method patent ductus arteriosus (PDA) occlusion.Thirty-one client-owned PDA.Records 31 which transarterial PDA an attempted were reviewed.All had type II PDA, 27 having IIA morphology and 4 IIB morphology. Appropriate device deployment achieved 29 dogs. Postdeployment angiography 21 documented complete 10 dogs, trivial residual flow 5 mild 2 moderate 3...