A5060551512- Cardiovascular Conditions and Treatments
- Neural and Behavioral Psychology Studies
- Congenital Heart Disease Studies
- Behavioral Health and Interventions
- Cardiac Arrhythmias and Treatments
- EEG and Brain-Computer Interfaces
- Sport Psychology and Performance
- Motivation and Self-Concept in Sports
- Motor Control and Adaptation
- Sports Performance and Training
- Mechanical Circulatory Support Devices
- Cardiovascular Function and Risk Factors
- Congenital heart defects research
- Cardiac electrophysiology and arrhythmias
- Cardiac Valve Diseases and Treatments
- Children's Physical and Motor Development
- Intracranial Aneurysms: Treatment and Complications
- Lymphatic Disorders and Treatments
- Muscle activation and electromyography studies
- Cardiovascular Effects of Exercise
- Mental Health Research Topics
- Human-Automation Interaction and Safety
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Hydraulic Fracturing and Reservoir Analysis
Auburn University
2016-2025
Washington University in St. Louis
2025
University of Alabama at Birmingham
2024
University of Colorado Denver
2012-2024
Children's Hospital Colorado
2023-2024
University of Kansas Medical Center
2022-2023
University of Virginia Health System
2023
University of Concepción
2023
Gadsden State Community College
2023
Regional Medical Center
2023
One characteristic of hypertension is a decreased endothelium-dependent nitric oxide (NO)-mediated vasodilation; however, the underlying mechanism complex. In endothelial cells (ECs), l -arginine substrate for both NO synthase (NOS) and arginase. Because arginase has recently been shown to modulate NO-mediated dilation coronary arterioles by reducing availability, we hypothesized that upregulation vascular in contributes vasodilation. To test this hypothesis, (mean arterial blood pressure...
Cerebral aneurysms treated by traditional endovascular methods using platinum coils have a tendency to be unstable, either due chronic inflammation, compaction of coils, or growth the aneurysm. We propose use alternate filling for treatment intracranial polyurethane-based shape memory polymer (SMP) foams. SMP polyurethane foams were surgically implanted in porcine aneurysm model determine biocompatibility, localized thrombogenicity, and their ability serve as stable filler material within an...
A growing body of research has illuminated beneficial effects a single bout physical activity (i.e., acute exercise) on cognitive function in school-age children. However, the influence exercise preschoolers’ not been reported. To address this shortcoming, current study examined 30-min function. Preschoolers’ was assessed following and sedentary period. Results revealed that, after engaging exercise, preschoolers exhibited markedly better ability to sustain attention, relative being ( p =...
Appropriate statistical analysis is essential for accurate and reliable research. Statistical practices have an immediate impact on the perceived results of a single study but also remote effects dissemination information among scientists cumulative nature To accurately quantify potential problems facing field motor learning, we systematically reviewed publications from seven journals over past 2 years to find experiments that tested different training conditions delayed retention transfer...
Background Published information regarding survival and long‐term cardiac remodeling after patent ductus arteriosus ( PDA ) closure in dogs is limited. Objectives To report outcome identify prognostic variables with , to risk factors for persistent a minimum of 12 months follow‐up closure. Animals Five hundred twenty client‐owned dogs. Methods Retrospective review medical records 520 . Outcome was determined by contacting owners veterinarians. Dogs ≥ were asked return re‐evaluation. Results...
Chylothorax is a devastating disease, and the success rates from either medical or surgical management are less than satisfactory. In some animals with chylothorax, thickening of pericardium occurs that associated chronic irritation induced by chyle. We hypothesized pericardial would lead to increased right‐sided venous pressures abnormal act impede drainage chyle via lymphaticovenous communications after thoracic duct (TD) ligation. also serosanguineous effusions occurred TD ligation could...
The functional and phenotypic characteristics of Ly-4(CD4)+ Ly-2(CD8)+ T cells were studied after induction murine AIDS with LP-BM5 leukemia virus. Assays spleen for their ability to generate in vitro CTL responses TNP-modified autologous (self + x CTL) alloantigens (allo showed that self greatly impaired at 3 4 wk postinfection undetectable thereafter. Allo normal wk, but reduced 8 9 absent 14 postinfection. This sequential loss allo was related a selective defect Th cell function...
Cardiovascular disease risk factors, such as diabetes, hypertension, dyslipidemia, obesity, and physical inactivity, are all correlated with impaired endothelial nitric oxide synthase (eNOS) function decreased (NO) production. NO-mediated regulation of mitochondrial biogenesis has been established in many tissues, yet the role eNOS vascular dynamics is unclear. We hypothesized that genetic deletion 3-day (NOS) inhibition rodents would result defunct fission/fusion autophagy profiles within...
The endovascular delivery of platinum alloy bare metal coils has been widely adapted to treat intracranial aneurysms. Despite the widespread clinical use this technique, numerous suboptimal outcomes are possible. These may include chronic inflammation, low volume filling, coil compaction, and recanalization, all which can lead aneurysm recurrence, need for retreatment, and/or potential rupture. This study evaluates a treatment alternative in polyurethane shape memory polymer (SMP) foam is...
Current endovascular therapies for intracranial saccular aneurysms result in high recurrence rates due to poor tissue healing, coil compaction, and aneurysm growth. We propose treatment of using shape memory polymer (SMP) foam improve clinical outcomes. SMP foam-over-wire (FOW) embolization devices were delivered vitro vivo porcine models evaluate device efficacy, occlusion, acute clotting. FOW demonstrated effective delivery stable implantation vitro. In successfully occluded with...