Sheng Wang

ORCID: 0000-0001-9923-4381
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Research Areas
  • Traditional Chinese Medicine Analysis
  • Plant biochemistry and biosynthesis
  • Natural product bioactivities and synthesis
  • Genomics and Phylogenetic Studies
  • Bioactive Compounds and Antitumor Agents
  • Biological and pharmacological studies of plants
  • Ginseng Biological Effects and Applications
  • Pharmacological Effects of Natural Compounds
  • Metabolomics and Mass Spectrometry Studies
  • Phytochemistry and Biological Activities
  • Food Quality and Safety Studies
  • Traditional Chinese Medicine Studies
  • Morinda citrifolia extract uses
  • Genetic diversity and population structure
  • Allelopathy and phytotoxic interactions
  • Medicinal Plant Pharmacodynamics Research
  • Plant tissue culture and regeneration
  • Isotope Analysis in Ecology
  • Plant-Microbe Interactions and Immunity
  • Ecology and Conservation Studies
  • Plant Pathogenic Bacteria Studies
  • Phytochemical compounds biological activities
  • Plant Gene Expression Analysis
  • Phytochemicals and Antioxidant Activities
  • Plant Parasitism and Resistance

Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025

Ministry of Agriculture and Rural Affairs
2023-2025

Tobacco Research Institute
2020-2025

China Academy of Chinese Medical Sciences
2020-2025

Jiangsu University
2025

Guangdong Pharmaceutical University
2024

Anhui Medical University
2022-2024

Shanghai Pulmonary Hospital
2024

Tongji University
2024

University of Washington
2022-2023

Abstract Background Atractylodes DC is the basic original plant of widely used herbal medicines “Baizhu” and “Cangzhu” an endemic genus in East Asia. Species within have minor morphological differences, universal DNA barcodes cannot clearly distinguish systemic relationship or identify species genus. In order to solve these question, we sequenced chloroplast genomes all using high-throughput sequencing. Results The results indicate that genome has a typical quadripartite structure ranges...

10.1186/s12864-021-07394-8 article EN cc-by BMC Genomics 2021-02-04

This study tested extracts from New Zealand seaweed Undaria pinnatifida containing fucoxanthin, in parallel with pure nine human cancer cell lines, for anticancer activity. Growth inhibition effects of were found all types lines dose- and time- dependent manners. Cytotoxicity fucoxanthin three non-cancer was also tested. Compared our low level to be more effective inhibiting the growth lung carcinoma, colon adenocarcinoma neuroblastoma. Our results suggest that is a functional biomaterial...

10.3390/jfb5020029 article EN cc-by Journal of Functional Biomaterials 2014-03-31

The Chinese yam, an important orphan crop with both high nutrient and health promoting value, is mainly produced in the Yellow-Huai-Hai plain near river basins China. protected designation of origin (PDO)-labeled yam differs greatly from others market acceptance price, which has led to fakes need for reliable authentication methods. Hence, stable isotope ratios δ13C, δ15N, δ2D, δ18O 44 multielemental contents were used explore geographical origins effect environmental factors. Twenty-two...

10.1016/j.fochx.2023.100678 article EN cc-by-nc-nd Food Chemistry X 2023-04-17

The lily, valued for its edibility and medicinal properties, is rich in essential nutrients. However, storage conditions sulfur fumigation during processing can degrade key nutrients like polysaccharides, phenols, dioxide. To address this, we applied a deep learning model combined with hyperspectral imaging the rapid prediction of nutrient quality. CLSTM (convolutional neural network-long short-term memory) model, utilizing variable combination population analysis (VCPA) wavelength...

10.3390/foods14050825 article EN cc-by Foods 2025-02-27

Shikonin and its derivatives are the most abundant naphthoquinone pigments formed in species of medicinally economically valuable Boraginaceae. A key step shikonin biosynthetic pathway, namely C-3′′ hydroxylation prenylated phenolic intermediate geranylhydroquinone, is expected to be catalyzed by a cytochrome P450. To identify P450 candidates with transcription profiles similar those genes known involved biosynthesis, we carried out coexpression analysis transcriptome data sets...

10.1104/pp.18.01056 article EN PLANT PHYSIOLOGY 2018-11-29

Aims: Most chemotherapeutic agents exploit apoptotic signaling to trigger cancer cell death, which frequently results in drug resistance. Necroptosis, a nonapoptotic form of regulated offers an alternative strategy eradicate apoptosis-resistant cells. We previously reported natural necroptosis inducer 2-methoxy-6-acetyl-7-methyljuglone (MAM) A549 lung The current study is designed investigate the detailed necroptotic and its cytotoxicity on drug-resistant Furthermore, vivo anticancer effects...

10.1089/ars.2017.7376 article EN Antioxidants and Redox Signaling 2018-12-15

Arnebiae Radix is a traditional medicine with pleiotropic properties that has been used for several 100 years. There are five species of Arnebia in China, and the two euchroma guttata source plants according to Chinese Pharmacopoeia. Molecular markers permit identification facilitate studies genetic diversity divergence wild populations these have not yet developed. Here, we sequenced chloroplast genomes 56 samples using genome skimming methods. The exhibited quadripartite structures lengths...

10.3389/fpls.2022.920826 article EN cc-by Frontiers in Plant Science 2022-06-09

This paper analyzed life form, habitats and environmental stresses of medicinal plants algal fungi collected in Chinese Pharmacopoeia(2015). ①It was found that only 0.94% the mainly cultivated field. The most common are divided into two types: those whose natural forest margins/undergrowth(about 42.53%) roadside, hillside, wasteland/sand(about 43.78%). former faces such as weak light, pests diseases; latter often main drought, strong ultraviolet radiation, high temperature, low...

10.19540/j.cnki.cjcmm.20200302.101 article EN PubMed 2020-05-01

Bunge (Danshen) is a traditional Chinese herb with significant medicinal value. The yield and quality of Danshen are greatly affected by climatic conditions, in particular high temperatures. Heat shock factors (Hsfs) play important regulatory roles plant response to heat other environmental stresses. However, little currently known about the role played

10.3390/ijms24108461 article EN International Journal of Molecular Sciences 2023-05-09

Rapidly generated scRNA-seq datasets enable us to understand cellular differences and the function of each individual cell at single-cell resolution. Cell-type classification, which aims characterizing labeling groups cells according their gene expression, is one most important steps for analysis. To facilitate manual curation process, supervised learning methods have been used automatically classify cells. Most existing approaches only utilize annotated in training step while ignoring more...

10.1093/bioinformatics/btac007 article EN Bioinformatics 2022-01-04

Fagopyrum dibotrys, being native to southwest China, is widely distributed in Yunnan, Guizhou Provinces and Chongqing City. However, the quality of medicinal materials growing different origins varies greatly, cannot meet market demand for high-quality F. dibotrys. In this study, 648 metabolites were identified, phenolic compounds dibotrys from clearly separated by principal component analysis (PCA). Our results suggested that differences can be elucidated via variations abundance flavonoid...

10.3390/metabo12090790 article EN cc-by Metabolites 2022-08-25
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