- Dermatology and Skin Diseases
- Skin Protection and Aging
- melanin and skin pigmentation
- Toxin Mechanisms and Immunotoxins
- Contact Dermatitis and Allergies
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Bee Products Chemical Analysis
- Tea Polyphenols and Effects
- Psidium guajava Extracts and Applications
- Allergic Rhinitis and Sensitization
- Acne and Rosacea Treatments and Effects
- Complementary and Alternative Medicine Studies
Givaudan (France)
2018-2024
(1) Background: Preclinical studies report that the ethanolic fraction from Mangifera indica leaves is a potential anti-acne agent. Nevertheless, biological activity of has scarcely been investigated, and additional data are needed, especially in clinical setting, for establishing actual effectiveness extract as an active component therapy. (2) Methods: The evaluation was carried out through different experimental phases, which comprised silico, vitro, ex vivo evaluations. (3) Results: In...
Summary Background Healthy skin is a delicate balance between renewal and microbiota homeostasis, its imbalance promotes premature aging dermatological disorders. Skin stem cells are key actors in this process but their sensitivity to external stressors such as UV reduces the power. The has been recently described active healthy skin, could trigger some Aims We hypothesized that reactivation of maintenance be disruptive strategy for younger healthier skin. thus developed new plant extract...
Microbiome supplementation initially targeted the gut microbiota but has since been extended to skin. A new category, psychobiotics, defined beneficial compounds with a positive action on microbiota, providing benefits host’s mental health. Pogostemon cablin leaf extract, proven alleviate scalp dryness, was clinically evaluated volunteers presenting dry flakes. metagenomics study and sebum production analysis were performed, coupled flakes scoring. The of extract emotions assessed through...
Dark spots, brown or hyperpigmented spots (HPS) are oval irregular areas of skin. Their emergence is associated with dysregulation the immune system, and may also be caused by a deficiency in stromal cell-derived factor-1, leading to perturbed melanogenesis accumulation melanosomes within neighboring keratinocytes. The skin microbiota (living microorganisms present on surface skin) known play essential roles maintaining homeostasis regulating system. Here, we investigated whether could role...
(1) Background: Ultraviolet radiation takes part in photoaging and pigmentation disorders on skin. Epigallocatechin gallate (EGCG) is a well-known brightening photoprotective compound but it faces limitations terms of stability solubility. (2) Methods: A more stable water-soluble glucoside called EGCG-G1 was obtained by enzymatic glucosylation EGCG. In vitro ex vivo experiments evaluated skin penetration, antioxidant activity, antimelanogenic properties compared to This gene expression study...
Our understanding of the interplay between skin microbiota and skin’s health status is growing. Consequently, cosmetics industry increasingly concerned with ensuring that beauty products do not adversely affect this health. Prior to implementing demanding sequencing-based analyses microbiota, an agile approach needed provide a first estimate short-term impact cosmetic ingredients on viability microbiota. A standardized methodology, including topical applications, swabbing, bacterial...