- Cerebrospinal fluid and hydrocephalus
- Fetal and Pediatric Neurological Disorders
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- MRI in cancer diagnosis
- Advanced MRI Techniques and Applications
- Vascular Malformations Diagnosis and Treatment
- Craniofacial Disorders and Treatments
- Neurosurgical Procedures and Complications
- Cancer, Hypoxia, and Metabolism
- Autoimmune Neurological Disorders and Treatments
- Head and Neck Surgical Oncology
- Brain Metastases and Treatment
- Vascular Malformations and Hemangiomas
- Meningioma and schwannoma management
- Medical Imaging Techniques and Applications
- Sinusitis and nasal conditions
- Radiomics and Machine Learning in Medical Imaging
- CNS Lymphoma Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Genetic Neurodegenerative Diseases
- Spinal Dysraphism and Malformations
Burdenko Neurosurgery Institute
2020-2023
Ministry of Health of the Russian Federation
2020-2023
National Medical Research Center of Cardiology
2021
The aim of the study was to evaluate role pseudocontinuous arterial spin labeling perfusion (pCASL-perfusion) in preoperative assessment cerebral glioma grades. group consisted 253 patients, aged 7-78 years with supratentorial gliomas (65 low-grade (LGG), 188 high-grade (HGG)). We used 3D pCASL-perfusion for each patient order calculate tumor blood flow (TBF). obtained maximal (maxTBF) small regions interest (30 ± 10 mm2) and then normalized absolute maximum (nTBF) that contralateral...
The first aim of this study was to compare the intratumoral and peritumoral blood flow parameters in glioblastomas brain metastases measured by pseudocontinuous arterial spin labeling MRI (3D pCASL). second determine whether pCASL could aid identifying source metastases. This included 173 patients aged 12 83 years (median age-61 years), who were observed at National Medical Research Center for Neurosurgery. All underwent preoperative with perfusion. Thereafter operated on received...
Introduction: The prediction of the fluorescent effect 5-aminolevulinic acid (5-ALA) in patients with diffuse gliomas can improve selection patients. degree enhancement has been reported to predict 5-ALA fluorescence, while, at same time, rarer cases fluorescence have described non-enhancing gliomas. Perfusion studies, particular arterial spin labeling perfusion, demonstrated high efficiency determining malignancy brain and may be better for predicting than contrast enhancement. aim study...
Aim . To study the role of CT perfusion in differential diagnosis histological subtypes supratentorial malignant gliomas and to determine degree their malignancy. Materials methods The included 34 patients (20 men 14 women, with an average age 52 years) newly detected supratenorial glial tumors, who subsequently underwent neurosurgical treatment NMIC neurosurgery verification diagnosis. Depending on diagnosis, three groups were identified: 1) anaplastic astrocytomas, 2) glioblastomas, 3)...
The possibility of developing extraventricular CSF pathways obstruction was demonstrated in the mid-20th century. development neuroimaging (mainly MRI) and endoscopic techniques made it possible to plan perform minimally invasive surgeries a narrow anatomical corridor achieve regression neurological symptoms. Purpose study: determine effectiveness surgery for hydrocephalus due idiopathic obstruction. Materials methods. Sixty-five patients with signs underwent examination surgical treatment...
Determine the influence of anatomical features and sizes lateral pocket with a defect on choice surgical access quality performed plastics.A retrospective analysis computed tomograms 38 patients who underwent treatment at Burdenko National Medical Research Center for Neurosurgery Ministry Health Russia about defects skull base in area sphenoid sinus. The were divided into three groups depending approach used (the 1st group), recurrence rate 2nd characteristics intraoperative visualization...
Clinical heterogeneity of lymphomas is associated with both tumor localization and its morphological immunological variants, moreover, in some cases paraneoplastic neurological syndromes (PNS). As the immuno-oncology advances, antineuronal antibodies were investigated. They are revealed case malignant neoplasms explain pathological mechanisms PNS development. The presented literature review provides data on main clinical laboratory characteristics classical characterizes determined patients PNS.
Objective To study the possibility of modern CT and MRI methods in diagnostics orbital venous varices (OVV), discover special characteristics these lesions concerning their hemodynamic differential diagnosis with other lesions. Material In period from 2012 to 2019 ten patients OVV were evaluated. Four them men, three - women children (boys aged 7, 10, 12 years). Age varied 7 75 years old (mediana 34). was performed on 9 using low dose protocol injecting contrast standard position (supine)...
The term "idiopathic hydrocephalus" in adults is a broader concept that includes larger spectrum of patients compared to normotensive hydrocephalus". It both young and elderly with various forms the disease, levels obstruction. Th ere no general classification approach treat such pathology. Endoscopic triventriculostomy idiopathic aqueductal stenosis cerebrospinal fluid shunting after positive test (tap test) evacuation hydrocephalus are proved be effective. In other pathway obstruction,...
Magnetic resonance imaging (MRI) is presently one of the main methods in diagnosis diseases associated with impaired fluid dynamics. Rapidly developing MRI technologies allow us to get more and information about functional organization both individual components entire cerebrospinal system (CSF) as a whole. One most common accompanied by CSF flow, where superiority among other non-invasive especially obvious, hydrocephalus. The review considers current capabilities assessing flow various forms
To study tissue characteristics of periventricular white matter in patients with open hydrocephalus using DWI MRI and their correlations CSF flow parameters.MRI was performed 55 (35 women 20 men) normal pressure hydrocephalus, as well 16 malignant occlusive interstitial edema (control group). We determined the between severity lesions parameters considering MR data. Dimensions ventricular system were assessed Evans' index, changes - visual four-level scale calculation apparent diffusion...
Venous angioma is a common developmental abnormality of the cerebral venous vessels. Usually, this pathology not accompanied by any symptoms and detected accidentally during MRI studies conducted for other reasons. In our article, we present rare clinical case when caused due to its location, which led development aqueductal stenosis.
Background. Hydrocephalus can be developing by a traumatic brain injury, intracranial hemorrhage, tumor, meningitis of congenital malformation the central nervous system. When cause hydrocephalus is unclear it supposed as idiopathic hydrocephalus. The most important classification features are etiology and level CSF obstruction. was improved developed with diagnostic surgical methods simultaneously. Currently, neurosurgeons have possibility for usage various techniques treatment their...
Introduction. The variety of clinical symptoms hydrocephalus due to obstruction at the level posterior cranial fossa cisterns, or extraventricular obstructive (EVOH), frequently goes against radiological semiotics and causes difficulties in developing patient management tactics.Materials methods. Analysis 65 patients treated for idiopathic cisternal CSF pathways FSAI N. Burdenko National Medical Research Center Neurosurgery Ministry Health Russia. All complained of, which could be caused by...
The development of research on CSF flow disorders made it possible initially to divide hydrocephalus into «communicating» and «non-communicating», subsequently distinguish the concepts «intraventricular» «extraventricular» obstruction. Improvement radiological imaging technologies has allowed determining exact level In some cases, combine signs different forms hydrocephalus. Their correct classification allows selecting type surgical treatment, which reduces rate complications patient»s...
Introduction. Idiopathic obstruction of the foramen Monroe is an extremely rare pathology in adults and accounts for 1 % all forms occlusive hydrocephalus. The largest described series patients with such includes 4 adult patients. Four types Monro have been distinguished: type A – atresia, or stenosis, B morphological (membrane), C functional obstruction, D patent foramen. These usually undergo endoscopic shunting surgery. Currently no algorithm exists treatment Materials methods. From 2004...
The aim of the study: to analyze features classification and diagnosis hydrocephalus in pediatric patients. Results. Hydrocephalus is a common pathology CSF system, often occurring childhood. central place examination this group patients taken by new neuroimaging technologies, particular, MRI. Pediatric have specific regarding MRI studies. This review presents research protocol modern children. Conclusion. Examination for should be based on estimated etiology. When conducting an study, must...