The aim the study. Improving effectiveness of treatment patients with recurrent oroantral fistula in conditions local tissue deficiency and chronic odontogenic maxillary sinusitis using a free autograft from wide fascia hip (fascia lata). Materials methods. Surgical was performed 6 scarring soft tissues, absence an oral vestibule, after repeated unsuccessful attempts at surgical fistulas (OAS). To eliminate OAS sinusitis, thigh used. Results. In all patients, 3 months treatment, closure...

To study the formation of alcohol preference in rats subjected to early social isolation, a possible model schizophrenia.The was carried out on 45 Wistar male rats, aged 21--24 days. The experimental animals were dropped from parental cells individual for 35 days, control kept standard conditions (5 per cage). Allanimals forced drinking three and ahalf months according following scheme: access the15% ethanol solution (Monday, Wednesday, Friday), deprivation (Tuesday, Thursday), free water...

Defects localized in the frontal sinus are difficult for surgical treatment, since there is a large number of anatomical variations structure naso-frontal canal and itself. With development endoscopic technology paying attention to modern tendency minimal invasive surgery, new approaches reach sinus, such as approach according Draf I-III combined were developed put into practice.To summarize analyze results treatment nasal liquorrhea with localization defect using endonasal intra-extranasal...

OBJECTIVE To determine the risk factors of multiple skull base defects, as well features diagnosis and treatment this pathology. MATERIAL AND METHODS A retrospective analysis included 39 patients who underwent surgery for nasal CSF leakage at Burdenko Neurosurgical Center in 2000-2019. The study recruited with simultant defects. RESULTS Traumatic defects were observed 23 (59%) patients, spontaneous - 16 (41%) cases. All endoscopic endonasal closure autografts. CONCLUSION Multiple are more...

Encephalocele or craniocerebral hernia is a disease in which there prolapse of the meninges and structures brain through skull defect. Clinically, they are manifested by violation nasal breathing, deformation naso‑ethmoid region, liquorrhea. Various inflammatory complications (meningitis, meningoencephalitis, ventriculitis, abscess) can occur against background persistent hernia, while mortality 8–10 %. Basal encephalocele rare pathology that requires an integrated approach specialized...

Basal encephaloceles (skull base hernias) are a rare pathology manifested by prolapse of altered membranes and brain tissue through bone defect the skull base. Endoscopic access is safer currently used as method choice in treatment this pathology. Available literature studies do not cover quality life these patients at follow-up. There controversy regarding impact endoscopic on growth centers facial skeleton. Material methods. A retrospective analysis series 100 aged 0 to 18 years with basal...

Surgical treatment of cerebellopontine angle tumors is a relevant and deeply studied topic modern neurosurgery. Among brain tumors, account for 6–10 %. One the important problems dysfunction caudal group nerves, which often occurs in postoperative period, manifested by bulbar disorders varying severity. The incidence patients with benign neoplasms before surgery ranges from 2 to 53 % directly depends on tumor size, degree compression stem stretching nerves. After surgery, varies 0 58...

Basal encephalocele is a rare condition manifested by prolapse of altered meninges and brain structures through bony defect in the skull base. Transcranial, endoscopic transnasal, combined approaches are used basal treatment. Often, comprehensive approach involving neurosurgeons, otorhinolaryngologists, ophthalmologists, maxillofacial surgeons, anesthesiologists required. A number complications may occur during surgery, including potentially fatal ones. The purpose study: To analyze our...

According to various authors, the rate of sphenoid sinus defects ranges from 15 26%. In sinus, most common defect localization is lateral recess - 35.3%. Regardless etiology and pathogenesis cerebrospinal fluid (CSF) leak, treatment approach aimed at plastic closure defect. Surgery in this area associated with a high recurrences (25%) due complex anatomical landscape inapplicability direct approach.The study purpose was analyze our own experience treating patients CSF leak...

The study aim was to analyze our own experience in treating patients with complex skull base defects accompanied by pneumocephalus and, based on the findings, develop an optimal treatment approach for this pathology.We retrospectively reviewed a series of 30 who underwent inpatient at Burdenko Neurosurgical Institute period from 2001 2017. We analyzed demographic characteristics (gender, age), clinical data (etiology, somatic and neuropsychiatric status, radiological data), aspects...

Last years the intake of energy drinks (drinks containing caffeine and alcohol) both in young men women has been increased. However investigators do not pay attention to analysis gender differences. The goal study was investigation ethanol influence on alcohol preference formation behavior male female rats under conditions long-term experiment. It found that six month caffeine, their combination led increase rats. Alcohol formed earlier consumed with ethanol, later ethanol. In animals strong...

The main stages of endoscopic skull base repair in patients with cerebrospinal fluid (CSF) leakage are identification bone boundaries the fistula and its closure by auto- allografts. Fibrin glue can be used to fix plastic materials additionally seal defect.To analyze efficacy safety Vivostat autologous fibrin for nasal CSF compare postoperative outcomes after defect allogeneic glue.A retro- prospective analysis included 56 who were treated at Burdenko Neurosurgery Center between January 2021...

Neurofibroma is a benign tumor that can develop from any peripheral, cranial, or autonomic nerve has Schwann sheath. Neurofibromas form sporadically in type I neurofibromatosis. of the nasal cavity and paranasal sinuses very rare; only few cases have been described world literature. This article presents case diagnosis successful endoscopic treatment synonasal neurofibroma. Clinical case. A 51-year-old woman applied to N.N. Burdenko National Scientific Practical Center for Neurosurgery with...

Background. Endoscopic skull base reconstruction of large defects is a difficult issue in neurosurgery, as there are problems associated with wide dural resection, intra-arachnoid dissection (due to removal the meningocele or resection an intracranially spreading tumor), and exposure high-flow cerebrospinal fluid within cisterns. But perhaps most significant influence larger nonvascularized reconstructive bed – on one side sinus cavity (air) other. The study objective analyze our own...

Determine the influence of anatomical features and sizes lateral pocket with a defect on choice surgical access quality performed plastics.A retrospective analysis computed tomograms 38 patients who underwent treatment at Burdenko National Medical Research Center for Neurosurgery Ministry Health Russia about defects skull base in area sphenoid sinus. The were divided into three groups depending approach used (the 1st group), recurrence rate 2nd characteristics intraoperative visualization...

Tinnitus is one of the most common otological symptoms and can be defined as conscious perception sound lasting more than 5 minutes in absence an external auditory stimulus. Based on review articles, a comparative analysis modern methods diagnosis treatment tinnitus was carried out order to substantiate effective promising algorithms for providing care patients. Diagnosis includes taking anamnesis, assessing severity using questionnaires, otoscopy, hearing examination, performing additional...

The objective of the present study was to elucidate causes late diagnostics vestibular shwannomas based on results analysis medical histories patients admitted Academician N.N. Burdenko National Medical Research Centre Neurosurgery for management this condition.We undertook retrospective review a series 192 cases in treated at 2015. included demographic characteristics as well their anamnestic and clinical data.A total 55 (29%) were found have small tumours (Samii T1-T3) whereas 137 (71%)...

# O7.1 ALCOHOL USE DISORDERS IN PATIENTS SEEKING TREATMENT FOR CANNABIS DEPENDENCE: CLINICAL CHARACTERISTICS {#article-title-2} Background. ECA and NESARC epidemiological studies found that alcohol use disorders (AUD) were frequently associated with cannabis abuse/dependence. However, no study investigated AUD correlates in patients seeking treatment for dependence, without severe mental illness. Methods. All consecutively outpatients dependence (DSM-IV criteria) the substance abuse...