A5072311733- Pituitary Gland Disorders and Treatments
- Meningioma and schwannoma management
- Head and Neck Surgical Oncology
- Glioma Diagnosis and Treatment
- Growth Hormone and Insulin-like Growth Factors
- Cerebrospinal fluid and hydrocephalus
- Adrenal and Paraganglionic Tumors
- Neurosurgical Procedures and Complications
- Sinusitis and nasal conditions
- Electrolyte and hormonal disorders
- Intracranial Aneurysms: Treatment and Complications
- Neurofibromatosis and Schwannoma Cases
- Neuroendocrine Tumor Research Advances
- Myasthenia Gravis and Thymoma
- Neuroblastoma Research and Treatments
- Ophthalmology and Eye Disorders
- Vascular Malformations Diagnosis and Treatment
- Infectious Diseases and Tuberculosis
- Oral and Maxillofacial Pathology
- Brain Metastases and Treatment
- Thyroid Disorders and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Adrenal Hormones and Disorders
- Management of metastatic bone disease
- Teratomas and Epidermoid Cysts
National Guard Military Academy of Ukraine
2023-2025
Burdenko Neurosurgery Institute
2016-2025
Ministry of Health of the Russian Federation
2018-2025
Peoples' Friendship University of Russia
2019-2020
Russian Academy of Sciences
2014
<title>Abstract</title> Titanium alloys and nickel-based stainless steels are attractive materials for the aerospace industry because of high-strength, heat resistance, corrosion resistance. However, these notorious poor thermal properties classified as difficult-to-machine materials. The problems attributed to high specific energy large amount cutting fluid consumed. Paper presents results elimination coolants by solid lubricants (SLs) in diamond grinding titanium alloy VT22 heat-resistant...
Combination of pituitary adenomas with meningiomas or vestibular schwannomas is a rare occurrence: in scientific literature, only individual cases small case series are described. The article presents clinical observation female patient who underwent surgery and radiotherapy due to hormonally inactive adenoma neurofibromatosis type 2 (intracranial meningioma neurinoma (schwannoma)) found during follow-up exam. A combination histologically different intracranial tumors (pituitary adenoma,...
Background. The term “aggressive pituitary adenoma” arose as a result of transforming the “atypical adenoma”, which was used in WHO classification for adenomas with specifications higher labeling index Ki-67 (≥3 %) and increased number mitoses expression p53 proteins. However, not all tumors these features were aggressive, currently, according to European Society Endocrinology Clinical Practice Guideline management aggressive carcinomas (2018), are labeled that have invasive unusually rapid...
Craniopharyngioma is a benign tumor in adults and children characterized by local invasion of surrounding brain structures. HARDI-CSD tractography one the modern MR methods for comprehensive visualization functionally significant conduction pathways. Objective. To determine possibility visualizing some structures chiasmatic-sellar region third ventricle (hypothalamic-pituitary tract (pituitary stalk), optic pathways, fornix, mammillothalamic tract) using patients with suprasellar...
Primary hypophysitis is a rare disease that usually diagnosed retrospectively after surgery for suspected tumors of the sellar region (pituitary adenomas, craniopharyngiomas, etc.). The most common variant primary forms lymphocytic hypophysitis, characterized by presence lymphocytes in inflammatory infiltrate. Granulomatous second disease, cause which remains unknown. Objective. To study frequency and nature clinical manifestations, features MRI brain, as well results neurosurgical treatment...
A promising direction in developing up-to-date transport vehicles is the use of transmissions, an essential element which a dual-clutch. Improving functional performance, energy efficiency, and environmental friendliness are relevant require appropriate research. The object study dry dual-clutch working with manual transmission high efficiency. In proposed design scheme, rotary lever movable carriage can change structural diagram force interaction between pressure spring clutch discs....
We recommend acromegaly to be ruled in all patients with characteristic changes appearance (A3). In without appearance, we rule out acromegaly, if several clinical signs suspicious for are present (B3). pituitary adenoma prolactin-secreting adenomas (C4). For laboratory confirmation of measure serum insulin-like growth factor-1 (IGF-1, somatomedin C) level obvious and/or a moderate increase IGF-1 levels (IGF-1 index less than 1.3), assess the response somatotropic hormone (GH) hyperglycemia...
One of the most serious/potentially fatal complications transsphenoidal surgery (TSS) is internal carotid artery (ICA) injury. Of 6230 patients who underwent TSS, ICA injury occurred in 8 (0.12%). The etiology, possible treatment options, and avoidance were analyzed. at two different stages: (1) during exposure sella floor dural incision over cavernous sinus (2) resection extension tumor. angiographic collateral blood supply was categorized as good, sufficient, nonsufficient to help with...
Pituitary adenomas are benign growths that invade the cavernous sinus (CS) in 10-15% of cases. There different types microsurgical and endoscopic approaches enabling resection tumors from CS cavity is a relatively small hard to reach anatomical structure comprising eloquent neurovascular structures.A study group included 97 patients with pituitary (PAs) invading CS. PAs were resected using an technique: through standard endonasal transsphenoidal approach 62 cases; lateral extended was used...
Thyrotropinomas (TSH-secreting tumors) are a rare type of pituitary adenomas, which account for about 0.5-2.0% all tumors. The criterion thyrotropinoma is visualization the tumor in presence normal or elevated level thyroid-stimulating hormone (TSH) blood and concentrations free T4 (fT4) T3 (fT3).To study clinical, diagnostic, morphological characteristics treatment outcomes TSH-secreting tumors.The included 21 patients aged from 15 to 67 years with adenoma TSH combined fT4 fT3 levels who...
Data on intra-abdominal hypertension [IAH] and secondary abdominal compartment syndrome [ACS] due to neurological insults are limited.This was a prospective observational study conducted between January 2010 2011 in the ICU [NICU]. Forty-one consecutive patients with sellar region tumors [SRT] were enrolled into study. If conservative therapy ineffective ACS, thoracic epidural anesthesia [EA] performed. Primary endpoint defined as efficacy of treatment EA IAH ACS; endpoint, influence ACS...
At present, pharmacological therapy of prolactinomas with dopamine agonists (DAs) is considered the treatment choice. In most cases, giant respond to and decrease in size during first months treatment. One rare but dangerous complications conservative invasive growth cerebrospinal fluid rhinorrhea.We present a retrospective analysis 15 patients macropropactinomas who underwent surgery for rhinorrhea developed due primary at Burdenko Neurosurgical Institute (BNI) period between 2005 2015. All...
Doppler ultrasound (DUS) has been widely used in neurosurgical practice to diagnose various cerebrovascular diseases. This technique is transsphenoidal surgery identify the localization of intracranial arteries when making an approach or during tumor resection.To cavernous segment internal carotid artery (ICA) and/or basilar endoscopic surgery, we a combined device on basis click line curette («Karl Storz») and 16 MHz probe (Lassamed). The was 51 patients both standard (23 cases) resection...
The structure of surgery pituitary adenomas has been fundamentally changed over the past decade. transnasal transsphenoidal approach is currently used to resect more than 95% adenomas. wide use endoscopy need for perioperative control intracranial pressure. While controlled hypertension was previously during microscopically bring suprasellar capsule and tumor remnants field vision, endoscopically resection implies that hypotension required achieve complete spreading capsule. External lumbar...
The pituitary stalk (PS) is a relatively thin bundle connecting the hypophyseal to gland; it consists of both axons hypothalamic nuclei (terminating in neurohypophysis) and system portal vessels. Compression PS by space-occupying lesion or its transection (forced intended) during surgery may lead development endocrine disorders: hypopituitarism, diabetes insipidus, hyperprolactinemia. modern literature lacks studies evaluating severity disorders depending on condition before after...