A5032695223- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Nosocomial Infections in ICU
- Respiratory Support and Mechanisms
- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Intensive Care Unit Cognitive Disorders
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Sepsis Diagnosis and Treatment
- Neurological Disorders and Treatments
- Traumatic Brain Injury Research
- Cerebrospinal fluid and hydrocephalus
- Thermal Regulation in Medicine
- Acute Ischemic Stroke Management
- Venous Thromboembolism Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Epilepsy research and treatment
- S100 Proteins and Annexins
- Antibiotic Resistance in Bacteria
- Atrial Fibrillation Management and Outcomes
- Trauma and Emergency Care Studies
- Optical Imaging and Spectroscopy Techniques
- Head and Neck Surgical Oncology
- Vascular Malformations Diagnosis and Treatment
- Cardiovascular and Diving-Related Complications
Burdenko Neurosurgery Institute
2016-2025
Ministry of Health of the Russian Federation
2020-2024
Russian Academy of Sciences
2014
Klebsiella pneumoniae, a member of the ESKAPE group bacterial pathogens, has developed multi-antimicrobial resistance (AMR), including to carbapenems, which increased alarmingly due acquisition carbapenemase genes located on specific plasmids. Four clinical K. pneumoniae isolates were collected from four patients neuro-intensive care unit in Moscow, Russia, during point prevalence survey. The AMR phenotype was estimated using Vitec-2 instrument, and whole genome sequencing (WGS) done...
Abstract Background The impact of infection prevention and control (IPC) programs in limited resource countries such as Russia are largely unknown due to a lack reliable data. aim this study is evaluate the effect an IPC program with respect healthcare associated (HAI) define incidence HAIs Russian ICU. Methods A pioneering was implemented neuro-ICU at Burdenko Neurosurgery Institute 2010 included hand hygiene, surveillance, contact precautions, patient isolation, environmental cleaning...
This research is aimed to study the clinical and MRI predictors of coma duration, intensity critical care, outcome traumatic brain injury (TBI).The data from 309 patients with TBI varying severity were included in analysis, whom 257 (86.7%) treated intensive care unit (ICU), including 196 (63.4%) admitted a comatose state lasting longer than 1 day. All underwent within 21 days after injury. findings classified according grading scale damage level localization proposed previously.The...
the study purpose was to evaluate efficacy of IntelliVent-ASV mode in maintaining target range PaCO2 patients with severe TBI.The included 12 TBI wakefulness level scored 4-9 (GCS). This a crossover design study. Two ventilation modes were consecutively used: and P-CMV, for h each. When using P-CMV mode, parameters set maintain 35-38 mm Hg. The involved Brain Injury algorithm. EtCO2 accordance delta PaCO2-EtCO2 35-38. At beginning each period every 3 hours, arterial blood gas composition...
Data on intra-abdominal hypertension [IAH] and secondary abdominal compartment syndrome [ACS] due to neurological insults are limited.This was a prospective observational study conducted between January 2010 2011 in the ICU [NICU]. Forty-one consecutive patients with sellar region tumors [SRT] were enrolled into study. If conservative therapy ineffective ACS, thoracic epidural anesthesia [EA] performed. Primary endpoint defined as efficacy of treatment EA IAH ACS; endpoint, influence ACS...
Paradoxical air embolism (PAE) is a rare life-threatening complication when emboli enter arteries of the systemic circulation and cause their occlusion. Here, we describe clinical case PAE developed during neurosurgery in patient sitting position. led to injuries cerebral blood vessels, coronary arteries, lungs, which caused death patient. An effective measure for preventing abandoning surgery position favor prone position.Парадоксальная воздушная эмболия (ПВЭ) - редкое, жизнеугрожающее...
Acute traumatic brain injury (TBI) can be accompanied by coagulopathy. In TBI, when an increased risk of hemorrhagic lesions in the tissue exists, keeping normal hemostasis is crucial. The aim : to determine incidence coagulopathy acute phase isolated TBI and identify correlation between types disorders severity TBI. Materials methods . We analyzed 323 case records patients with hospitalized Neurosurgery Center ICU from 2008 2016, 118 them were included study. Criteria for inclusion...
Intracranial hypertension is a commonly encountered neurocritical care problem. If first-tier therapy ineffective, second-tier must be initiated. In many cases, the full arsenal of established treatment options available. However, situations occasionally arise in which only narrow range available to neurointensivists. We present rare clinical scenario therapeutic hypothermia was method for controlling intracranial pressure and that demonstrates efficacy safety Thermogard (Zoll, Chelmsford,...
Autoregulation of cerebral blood flow (ACBF) is a system mechanisms for maintaining stable adequate perfusion the brain despite changes in systemic arterial pressure. In recent years, new data on numerous metabolic and regulation have been obtained, but role neurogenic has not yet fully understood and, therefore, considered clinical practice.The study aim was to assess effect anatomical injuries deep structures extent duration ACBF abnormalities model severe diffuse axonal injury (DAI).The...
Traumatic brain injury (TBI) is an independent risk factor for venous thromboembolism (VTE). This study aimed to determine the optimal timing initiating pharmacological thromboprophylaxis VTE in patients with isolated severe TBI using rotational thromboelastometry (ROTEM).
The first results of intracisternal administration verapamil for the prevention and treatment cerebral vasospasm (CVS) in patients acute period subarachnoid hemorrhage (SAH) after microsurgical clipping aneurysms are presented.Safety assessment method prolonged infusion (PII) verapamil.Over from May 2017 to December 2018, 42 were included study, who underwent aneurysm anterior segments Willis circle. Most (78.6%) operated during 6 days SAH. For each patient, a thin silicone catheter was...
Patients with traumatic brain injury (TBI) are at high risk of infection.To delineate infections in acute period TBI, association between intracranial lesion type and infection, as well to estimate treatment outcomes these patients depending on infection.This study included 104 TBI (80 men 24 women) aged 33.01±14.35 years. All met the inclusion criteria: admission within 72 hours after age 18-75 years, ICU-stay >48 hours, available MRI data. Mild, moderate severe were diagnosed 7%, 11% 82%...
Pulmonary embolism (PE) is a serious problem for neurosurgical patients because of high risk mortality and the need to choose effective safe anticoagulation.To analyze with PE after interventions.A prospective study was performed at Burdenko Neurosurgical Center between January 2021 December 2022. Inclusion criteria were disease PE.In accordance inclusion criteria, we analyzed 14 patients. Mean age 63 [45.8; 70.0] years. Four died. direct cause death in 1 case. occurred 5.14±3.68 days...
The spread of multidrug-resistant Gram-negative bacteria, which is associated with the distribution beta-lactamase genes and class 1 2 integrons, a global problem. In this study, in Moscow neurosurgery intensive care unit (neuro-ICU), high prevalence above-stated was found to be intestinal tracheal carriage. Seven-point surveys, included 60 patients neuro-ICU, were conducted weekly period from Oct. Nov. 2019. A total 293 clinical samples analyzed, including 146 rectal 147 swabs; 344 bacteria...