A5089262805- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Trauma and Emergency Care Studies
- Traumatic Brain Injury Research
- Sepsis Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Neurological Disorders and Treatments
- Respiratory Support and Mechanisms
- Venous Thromboembolism Diagnosis and Management
- Intensive Care Unit Cognitive Disorders
- S100 Proteins and Annexins
- Human Health and Disease
- Airway Management and Intubation Techniques
- Nosocomial Infections in ICU
- Physical Education and Training Studies
- Tracheal and airway disorders
- Neurosurgical Procedures and Complications
- Head and Neck Surgical Oncology
- Atrial Fibrillation Management and Outcomes
- Radiation Dose and Imaging
- Pharmaceutical Practices and Patient Outcomes
- Thermal Regulation in Medicine
- Cardiac Health and Mental Health
Burdenko Neurosurgery Institute
2013-2025
Ministry of Health of the Russian Federation
2018-2024
Institute of Experimental Cardiology
2006
This research is aimed to study the clinical and MRI predictors of coma duration, intensity critical care, outcome traumatic brain injury (TBI).The data from 309 patients with TBI varying severity were included in analysis, whom 257 (86.7%) treated intensive care unit (ICU), including 196 (63.4%) admitted a comatose state lasting longer than 1 day. All underwent within 21 days after injury. findings classified according grading scale damage level localization proposed previously.The...
The aim of this study was to estimate the prognostic value magnetic resonance imaging (MRI) classification traumatic brain lesion localization and levels in patients with a injury various severity few days three weeks after injury.The cohort 278 (TBI) aged 8-74 y.o. (average -31.4±13.8, median - 29 (21.3; 37.0) included analysis. TBI at admission varied from 3 15 Glasgow coma scores (GCS) 8±4, 7 (5; 12). main indications conditions for MRI were: inconsistency between computed tomography (CT)...
the study purpose was to evaluate efficacy of IntelliVent-ASV mode in maintaining target range PaCO2 patients with severe TBI.The included 12 TBI wakefulness level scored 4-9 (GCS). This a crossover design study. Two ventilation modes were consecutively used: and P-CMV, for h each. When using P-CMV mode, parameters set maintain 35-38 mm Hg. The involved Brain Injury algorithm. EtCO2 accordance delta PaCO2-EtCO2 35-38. At beginning each period every 3 hours, arterial blood gas composition...
Acute isolated traumatic brain injury (TBI) is frequently associated with occurrence of hemostasis disorders, which may be accompanied hemorrhagic and ischemic events in the matter, hence, normal functioning blood coagulation system critical. Understanding pathophysiological mechanisms this phenomenon might help adequate prophylaxis secondary damage. Earlier, development disseminated intravascular syndrome (DIC) has been generally considered as a mechanism disorders during TBI. However, over...
Paradoxical air embolism (PAE) is a rare life-threatening complication when emboli enter arteries of the systemic circulation and cause their occlusion. Here, we describe clinical case PAE developed during neurosurgery in patient sitting position. led to injuries cerebral blood vessels, coronary arteries, lungs, which caused death patient. An effective measure for preventing abandoning surgery position favor prone position.Парадоксальная воздушная эмболия (ПВЭ) - редкое, жизнеугрожающее...
Acute traumatic brain injury (TBI) can be accompanied by coagulopathy. In TBI, when an increased risk of hemorrhagic lesions in the tissue exists, keeping normal hemostasis is crucial. The aim : to determine incidence coagulopathy acute phase isolated TBI and identify correlation between types disorders severity TBI. Materials methods . We analyzed 323 case records patients with hospitalized Neurosurgery Center ICU from 2008 2016, 118 them were included study. Criteria for inclusion...
Autoregulation of cerebral blood flow (ACBF) is a system mechanisms for maintaining stable adequate perfusion the brain despite changes in systemic arterial pressure. In recent years, new data on numerous metabolic and regulation have been obtained, but role neurogenic has not yet fully understood and, therefore, considered clinical practice.The study aim was to assess effect anatomical injuries deep structures extent duration ACBF abnormalities model severe diffuse axonal injury (DAI).The...
Traumatic brain injury (TBI) is an independent risk factor for venous thromboembolism (VTE). This study aimed to determine the optimal timing initiating pharmacological thromboprophylaxis VTE in patients with isolated severe TBI using rotational thromboelastometry (ROTEM).
Neurosurgical interventions within the ventral surface of clivus and upper cervical vertebrae in childhood are sometimes carried out through transoral approach. In this situation, tracheostomy is safer for airway protection mechanical ventilation compared to prolonged intubation. The world experience percutaneous dilation pediatric patients limited due anatomical physiological features, such as difficult orientation landmarks, high mobility trachea small tracheal lumen. Also, easily...
Patients with traumatic brain injury (TBI) are at high risk of infection.To delineate infections in acute period TBI, association between intracranial lesion type and infection, as well to estimate treatment outcomes these patients depending on infection.This study included 104 TBI (80 men 24 women) aged 33.01±14.35 years. All met the inclusion criteria: admission within 72 hours after age 18-75 years, ICU-stay >48 hours, available MRI data. Mild, moderate severe were diagnosed 7%, 11% 82%...
Pulmonary embolism (PE) is a serious problem for neurosurgical patients because of high risk mortality and the need to choose effective safe anticoagulation.To analyze with PE after interventions.A prospective study was performed at Burdenko Neurosurgical Center between January 2021 December 2022. Inclusion criteria were disease PE.In accordance inclusion criteria, we analyzed 14 patients. Mean age 63 [45.8; 70.0] years. Four died. direct cause death in 1 case. occurred 5.14±3.68 days...