A5077042125- Malaria Research and Control
- Mosquito-borne diseases and control
- HIV Research and Treatment
- Drug Transport and Resistance Mechanisms
- Toxoplasma gondii Research Studies
- Invertebrate Immune Response Mechanisms
Universität Hamburg
2021-2023
Bernhard Nocht Institute for Tropical Medicine
2021-2023
Centre for Structural Systems Biology
2021-2023
Mature gametocytes of Plasmodium falciparum display a banana (falciform) shape conferred by complex array subpellicular microtubules (SPMT) associated with the inner membrane (IMC). Microtubule-associated proteins (MAPs) define MT populations and modulate interaction pellicular components. Several MAPs have been identified in Toxoplasma gondii, homologues can be found genomes
During the symptomatic human blood phase, malaria parasites replicate within red cells. Parasite proliferation relies on uptake of nutrients, such as amino acids, from host cell and plasma, requiring transport across multiple membranes. Amino acids are delivered to parasite through parasite-surrounding vacuolar compartment by specialized nutrient-permeable channels erythrocyte membrane parasitophorous vacuole (PVM). However, further plasma (PPM) is currently not well characterized. In this...
ABSTRACT Mature gametocytes of Plasmodium ( P .) falciparum display a banana (falciform) shape conferred by complex array subpellicular microtubules (SPMT) associated to the inner membrane (IMC). Microtubule proteins (MAPs) define MT populations and modulate interaction pellicular components. Several MAPs have been identified in Toxoplasma gondii homologues can be found genome species, but function these for asexual sexual development malaria parasites is still unknown. Here we novel MAP,...
ABSTRACT During the symptomatic human blood phase, malaria parasites replicate within red cells. Parasite proliferation relies on uptake of nutrients, such as amino acids, from host cell and plasma, requiring transport across multiple membranes. Amino acids are delivered to parasite through surrounding vacuolar compartment by specialized nutrient-permeable channels erythrocyte membrane parasitophorous vacuole (PVM). However, further acid plasma (PPM) is currently not well characterized. In...