The PtRu/C HOR catalyst weakens the metal–H interaction and boosts cell performance of APEFC to 1 W cm⁻².

Anion exchange membrane fuel cells (AEMFCs) have been developed as promising energy conversion devices for stationary and mobile applications due to their potentially low cost. To realize high-performance AEMFCs, new polymeric membranes are needed that highly conductive chemically stable. Here we report a systematic study of anion (AEMs) with multiple cations per side chain site demonstrate how this motif can boost both the conductivity stability poly(2,6-dimethyl-1,4-phenylene oxide)-based...

A novel silver-mediated highly selective C–H/N–H oxidative cross-coupling/cyclization between 2-aminopyridines and terminal alkynes has been demonstrated. This approach provided a simple way to construct heteroaromatic imidazo[1,2-a]pyridines. By using this protocol, the marketed drug zolimidine (antiulcer) could be synthesized easily.

Anion exchange membranes (AEMs) are a promising class of materials that enable non-noble metals to be used as catalysts in fuel cells. Compared their acidic counterparts, typically Nafion and other perfluorosulfonate-based membranes, the low OH– conductivity AEMs remains concern these developed for practical applications. Cross-linked macromolecular structures popular way optimize trade-off between ionic water swelling with high ion capacities (IECs). However, common cross-linked (e.g.,...

A series of tough and chemically stable semi-interpenetrating network anion exchange membranes (SIPN AEMs) composed a rigid ion-conductive component, quaternized poly(2,6-dimethyl phenylene oxide) (QAPPO), hydrophilic, cross-linked, flexible poly(ethylene glycol)-co-poly(allyl glycidyl ether) (xPEG–PAGE) component were synthesized. The SIPN AEMs containing both polymer constituents exhibited outstanding mechanical strength flexibility much tougher than conventional QAPPO membranes....

Alkaline polymer electrolytes (APEs) are a new class of polyelectrolytes enabling the use nonprecious metal catalysts in electrochemical devices, such as fuel cells and water electrolyzers. However, current development APEs is facing severe difficulty, conductivity–stability dilemma. Specifically, to acquire high ionic conductivity, backbone has be grafted with enough cationic functional groups, typically quaternary ammonium (–NR3+), but modification structure damaged chemical inertness...

A series of chemically stable and ionically conductive side-chain anion exchange membranes (AEMs) based on poly(2,6-dimethyl-1,4-phenylene oxide) (PPO) backbones alkyltrimethylammonium cations are reported in this work. Two groups with n-propyl (C3) n-pentyl (C5) alkyl chains were tethered onto PPO through secondary amine moieties, resulting two AEMs, that is, NC3Q-PPO NC5Q-PPO NC5 Q-PPO. In comparison to benzylic QA (e.g., benzyltrimethylammonium quarternized (QPPO)...

Mechanically tough, cross-linked anion exchange membranes (AEM) based on poly(2,6-dimethylphenylene oxide) (PPO) were achieved by introducing a hydrophilic and flexible Jeffamine (O,O′-bis(2-aminopropyl)polypropylene glycol-block-poly(ethylene glycol)-block-polypropylene glycol 500) cross-linker into the cationic macromolecular network. The AEMs demonstrated outstanding strength flexibility mechanically tougher than AEM samples benzyltrimethylammonium (BTMA) functionalized PPO alone....

Abstract Early diagnosis and intervention of Alzheimer’s disease (AD) are particularly important to delay the pathological progression. Although fluorescent probes have been widely employed for investigating diagnosing AD, their biological applications significantly restricted due low penetration ability blood–brain barrier (BBB) in vivo. In this study, we reported first Golgi-targeted two-photon (TP) probe, DCM-DH, detecting viscosity Golgi apparatus. The probe was rationally designed...

Alkaline polymer electrolyte fuel cells (APEFCs) promise the use of nonprecious metal catalysts and thus have attracted much research attention in recent decade. Among challenges developing practical APEFC technology, chemical stability alkaline electrolytes (APEs) seems to be rather difficult. Research found that, upon attachment a cationic functional group, an originally stable backbone, such as polysulfone (PSF), would degrade environment. In present work, we try employ poly(ether ether...

Aromatic ether-based alkaline polymer electrolytes (APEs) are one of the most popular types APEs being used in fuel cells. However, recent studies have demonstrated that upon grafted by proximal cations some polar groups backbone such can be attacked OH(-), leading to degradation an environment. To resolve this issue, we performed a systematic study on six APEs. We first replaced polysulfone (PS) with polyphenylsulfone (PPSU) and polyphenylether (PPO), whose molecular structures contain...

A series of ether-bond free polybenzimidazole (PBI) bearing pendant imidazolium groups (HIm-PBI and PIm-PBI) are synthesized via a low cost preparation process under mild reaction conditions. HIm-PBI PIm-PBI show excellent membrane forming property, flexible HIm-PBI- PIm-PBI-based membranes prepared by casting the polymer/dimethyl sulfoxide solution. For comparison, PBI without (I-PBI) was characterized in detail, I-PBI shows poor ability same HIm-PBI-based anion exchange (AEMs) with longer...

Abstract MALDI MSI has been recently applied as an innovative tool for detection of molecular distribution within a specific tissue. requires deposition organic compound, known matrix, on the tissue interest to assist analyte desorption and ionization, in which matrix crystal homogeneity size greatly influence imaging reproducibility spatial resolution MSI. In this work, homemade electrospray device was developed The could be used achieve 1 μm homogeneous crystals analysis. Moreover, it...

Hydrophobic side chains were employed to induce different patterns of microphase separation and cause conductive performance in alkaline polymer electrolytes.

Strophanthidin (SPTD), one of the cardiac glycosides, is refined from traditional Chinese medicines such as Semen Lepidii and Antiaris toxicaria, was initially used for treatment heart failure disease in clinic. Recently, SPTD has been shown to be a potential anticancer agent, but underlying mechanism action poorly understood. Herein, we explored molecular by which exerts effects A549 human lung adenocarcinoma cells means mass spectrometry-based quantitative proteomics combination with...

Abstract Quantitatively estimating the energy input from solar wind into magnetosphere on a global scale is still an observational challenge. We perform three‐dimensional magnetohydrodynamic (MHD) simulations to derive coupling function. Based 240 numerical test runs, function given by . study correlations between and wide variety of magnetospheric activity, such as indices D s t , K p ap AE AU AL polar cap index, hemispheric auroral power. The results indicate that this gives better than ε...

Abstract The numerical results from a physics‐based global magnetohydrodynamic (MHD) model are used to examine the effect of interplanetary magnetic field (IMF), solar wind dynamic pressure, and dipole tilt angle on size shape magnetopause. subsolar magnetopause is identified using plasma velocity density, cusps thermal whole determined with three‐dimensional streamlines traced through simulation domain. surface obtained simulations fitted function controlled by ten configuration parameters,...

To minimize the ohmic loss in cell voltage of fuel cells, electrolyte should be made as thin possible, particular when alkaline polymer electrolytes (APEs) are employed, where both mobility and concentration OH− relatively low. A practical strategy for fabricating APE membranes is to impregnate ionomers into an ultrathin, rigid framework (such a porous PTFE film), so that high ion conduction achieved by with ion-exchange capacity (IEC), while good mechanical stability provided robust host....

Abstract Gangliosides are a family of complex lipids that abundant in the brain. There is no doubt investigations about distribution gangliosides brian and relationship between Alzheimer’s disease profound. However, these full challenges due to structural complexity gangliosides. In this work, method for efficient extraction enrichment from brain was established. Moreover, obtained by matrix-assisted laser desorption ionization (MALDI) mass spectrometry imaging (MSI). It found...