A5070641966- Pharmaceutical Practices and Patient Outcomes
- Phytochemistry and Biological Activities
- Global Maternal and Child Health
- Malaria Research and Control
- Pharmaceutical Economics and Policy
- Drug-Induced Hepatotoxicity and Protection
- Natural product bioactivities and synthesis
- Natural Antidiabetic Agents Studies
- Phytochemistry and Bioactive Compounds
- Mosquito-borne diseases and control
- Chemical synthesis and alkaloids
- Ethnobotanical and Medicinal Plants Studies
- Neuropeptides and Animal Physiology
- Pharmaceutical Quality and Counterfeiting
- Synthesis and bioactivity of alkaloids
- Natural Compound Pharmacology Studies
- Pharmacological Effects of Natural Compounds
- Alkaloids: synthesis and pharmacology
- Botanical Research and Chemistry
- Complementary and Alternative Medicine Studies
- Pharmacovigilance and Adverse Drug Reactions
- Pharmacology and Obesity Treatment
- Phytochemistry and biological activity of medicinal plants
- Innovations in Medical Education
- Pain Mechanisms and Treatments
University of Ghana
2020-2024
Kwame Nkrumah University of Science and Technology
1998-2010
University of Strathclyde
1993-1999
Royal College of Physicians and Surgeons of Canada
1993
The anti-inflammatory activities of extracts from the resins four species plant family Burseraceae, Boswellia dalzielli, carteri (gum olibanum), Commiphora mukul, and incisa, were studied. aqueous B. C. mukul significantly inhibited both maximal edema response total during 6 h carrageenan-induced rat paw edema. octanordammarane triterpenes, man-sumbinone mansumbinoic acid, isolated resin separated tested. Administered prophylactically, mansumbinone proved to be more than 20 times less potent...
To assess the appropriateness of self-reported use anti-malarial drugs prior to health facility attendance, and management malaria in two facilities Ghana. A structured questionnaire was used collect data from 500 respondents who were diagnosed clinically and/or parasitologically for at Agogo Presbyterian Hospital Suntreso Polyclinic, both Ashanti Region Collected information included previous attending facilities, types used, how sources drugs. In addition, therapy given outcomes assessed....
The aqueous ethanolic extracts of Polygonum bistorta L. Polygonaceae, Guaiacum officinale Zygophyllaceae and Hamamelis virginiana Hamamelidaceae were screened for anti-inflammatory activity. Administered (100 200 mg kg-1, p.o.) before the induction carrageenan rat paw oedema, P. significantly suppressed both maximal oedema response total (monitored as area under time course curve). H. was inactive G. only active at kg-1. At kg-1 administered adjuvant arthritis, inhibited acute chronic phases...
Medicines can be taken by various routes of administration. These impact the effects and perceptions medicines. The literature about individuals' preferences for different administration is sparse, but indicates a potential influence culture. Our aim was to determine: (i) any association between one's culture preferred route medicine (ii) individual pain, efficacy, speed action acceptability when medicines are swallowed or placed in mouth, under tongue, nose, eye, ear, lungs, rectum, vagina,...
Although national and international efforts to combat malaria have intensified over the years, problems with availability, distribution, choice of antimalarials at medicine outlets in Africa continue exist. This article presents results an indicator-based assessment availability 130 licensed Ghana. We also discuss how antimalarial dispense conforms recommendations policy for therapy. Data were obtained through face-to-face interviews, by reviewing facility records, observing practices...
Background Reviewing the epidemiological profile of medication errors (MEs) reported by African countries and systems put in place to report such is crucial because reporting plays an important role improving patient safety. The objectives this study were characterize spontaneously MEs submitted VigiBase; World Health Organization (WHO) global database individual case safety reports, describe for these errors, explore challenges facilitators spontaneous understand potential patients. Methods...
Background: Medication errors (MEs) by caregivers at home are a cause of morbidity and mortality, shortly after discharge from the hospital. Objectives: The objective this study was to determine rate types MEs homes children discharged hospital in Ghana explore factors associated with these errors. Design: This cross-sectional infants review medication administration practices. Methods: Caregivers least 24 hours admission were interviewed their about assessed potential harm made using Harm...
Acute and sub-acute oral toxicity assessment of the aqueous root extract ofCryptolepis sanguinolenta was studied in Sprague Dawley rats for possible use as animal medication. The extract (250 - 3000 mg/kg, p.o) was administered daily a period 72 h (500 2000 14 days acute studies respectively. administration did not produce any physiological behavioural changes. In subacute however, dose-dependent increase number platelets (from vehicle-treated control value 353.00 ± 49.40 958.00 42.50...
Abstract Background Understanding the origin and evolution of education pharmacists is important for practice health system reforms. In Ghana, started in 1880s with training dispensers a government hospital. Over years, curriculum institutional arrangements changed currently are trained universities. this study we explored how why evolved Ghana. Methods We used case design to systematically describe Data was collected from October 2018 December 2019 through document review in-depth...
Uncorrected congenital heart lesions in children keep them a state of constant hypoxia with compromised quality life and reduced expectancy. This requires early diagnosis interventions including prevention treatment the resultant anaemia. Unfortunately, disease (CHD) often goes unrecognized thus untreated.We determined occurrence CHD below 15 years at Komfo Anokye Teaching Hospital (KATH), assessed prevalence relative iron deficiency anaemia that cohort use supplementation these patients.We...
Alchornea cordifolia (Schum. and Thonn.) Müll. Arg (Euphorbiaceae), a widely used traditional medicinal agent was assessed for possible toxicity in mice. We investigated the effect of ethanolic extract on blood cells chemistry, histology, relative weight selected organs Administration (250-2000 mg/kg, p.o daily) two weeks did not affect significantly organ weights, or renal function. Histology liver kidney at dose levels up to 1000 mg/kg normal similar vehicle- treated controls. However,...