A5029424358- Pharmacovigilance and Adverse Drug Reactions
- Vaccine Coverage and Hesitancy
- SARS-CoV-2 and COVID-19 Research
- Pharmaceutical studies and practices
- Pharmaceutical Practices and Patient Outcomes
- Pharmaceutical Economics and Policy
- Ethics in Clinical Research
- Influenza Virus Research Studies
- Pharmaceutical industry and healthcare
- Medication Adherence and Compliance
- Heparin-Induced Thrombocytopenia and Thrombosis
- Emergency and Acute Care Studies
- Clinical Reasoning and Diagnostic Skills
- Biomedical Ethics and Regulation
- Computational Drug Discovery Methods
- Mobile Health and mHealth Applications
- Medical Malpractice and Liability Issues
- Viral gastroenteritis research and epidemiology
- Malaria Research and Control
- Blood donation and transfusion practices
- Tuberculosis Research and Epidemiology
- Health Systems, Economic Evaluations, Quality of Life
- Data-Driven Disease Surveillance
- Social Media in Health Education
- Patient Safety and Medication Errors
University of Groningen
2022-2024
United States Food and Drug Administration
2020
Ministry of Food and Agriculture
2017-2019
Cohort event monitoring (CEM) is an intensive method of post-marketing surveillance for medicines safety. The based on prescription monitoring, which began in the 1970s, and has since been adapted by WHO safety used Public Health Programmes. CEM aims to capture all adverse events that occur a defined group patients after starting treatment with specific medicine during course routine clinical practice.The this study were describe experiences National Pharmacovigilance Centres (NCs) have...
With over 80% of children worldwide vaccinated, concerns about vaccine safety continues to be a public health issue. Ghana's Adverse Events Following Immunization surveillance started in 1978 with the objective promptly detect and manage AEFI cases either real or perceived. Periodic evaluation system is critical for optimal performance; hence we evaluated assess its attributes, usefulness system's performance meeting objectives.A case was defined as any untoward medical event occurring...
Background Reviewing the epidemiological profile of medication errors (MEs) reported by African countries and systems put in place to report such is crucial because reporting plays an important role improving patient safety. The objectives this study were characterize spontaneously MEs submitted VigiBase; World Health Organization (WHO) global database individual case safety reports, describe for these errors, explore challenges facilitators spontaneous understand potential patients. Methods...
Background: Medication errors (MEs) by caregivers at home are a cause of morbidity and mortality, shortly after discharge from the hospital. Objectives: The objective this study was to determine rate types MEs homes children discharged hospital in Ghana explore factors associated with these errors. Design: This cross-sectional infants review medication administration practices. Methods: Caregivers least 24 hours admission were interviewed their about assessed potential harm made using Harm...
The use of mobile phone technology for reporting adverse drug reactions (ADRs) in pharmacovigilance is relatively new.The objective the study was to explore challenges and facilitators Med Safety App ADRs Ghana. A comparative evaluation ADR reports received through app standard paper-based form also conducted.This a cross-sectional with purposive sampling technique. population persons who had downloaded launched Ghana 18 months before study.Of 350 participants, 121 provided answers...
Patient reporting of adverse drug reactions (ADRs) is low in low- and middle-income countries, part because poor awareness to report. With the increase mobile subscription, phones can be used as a platform disseminate information on ADRs. The aim this study was qualitatively assess potential using phone caller tunes (the message or sound hears before receiver answers call) encourage patient ADRs.A total 38 key informant interviews 12 focus group discussions (57 participants groups 4-5) were...
Background: Timely reporting of safety information post vaccination is pivotal for the success any program. Reports adverse events following immunization (AEFI) 6 different vaccinations from Ghana were analysed signals.Methods: De-identified data active surveillance AEFIs after 2009 AH1N1 influenza, yellow fever, meningitis, measles-rubella, pneumococcal-rotavirus and human papilloma virus used. All occurred between January 2010 December 2013. The ten most occurring each captured arranged...
Personalized feedback received for spontaneous adverse drug reaction (ADR) reports serves as motivation future reporting and the effectiveness of is dependent on medium used in delivering information.Explore expectation from patients ADR submitted to National Pharmacovigilance Centre (NPvC) Ghana preferred receiving information.Cross-sectional study using structured questionnaire administered through face-to-face interview August September 2016 selected by convenience sampling. Pearson...
The novel coronavirus disease 2019 (COVID-19) is an ongoing pandemic caused by severe acute respiratory syndrome 2 (SARS-CoV-2). There limited information on the safety of drugs used for treatment COVID-19.Objective this study to describe pattern stimulated spontaneous adverse drug reaction (ADR) reports received from healthcare professionals SARS-CoV-2 positive patients in Ghana and lessons learnt particularly low- middle-income countries.This a individual case (ICSRs) between 1st April...
Vaccines are important public health tools and formed part of the fight against COVID-19 pandemic. Five vaccines were given Emergency Use Authorization in Ghana deployed during Early phase trials mostly not conducted Africans. This study examines safety data their deployment under real-life conditions Ghana. analysed secondary on vaccine-related adverse events following immunization (AEFI) reported to Food Drugs Authority (GFDA) between March 2021 June 2022 using STATA. AEFIs coded with...
Adverse Drug Reactions (ADRs) can occur with all medicines even after successful extensive clinical trials. ADRs result in more than 10% of hospital admissions worldwide. In Ghana, there has been an increase 13 to 126 ADR reports per million population from 2012 2018. Surveillance System (ADRSS) also known as pharmacovigilance put place by the Ghana Food and Drugs Authority (FDA) collect manage suspected communicate safety issues healthcare professionals general public. The ADRSS Ho...
Abstract Drug regulatory institutions, infrastructures, and systems are becoming increasingly interconnected across national boundaries global in outlook. This process is reflected the broadening deepening application of principles practice Regulatory Reliance , parallel initiatives to strengthen capacities institutions low‐ middle‐income countries (LMICs). Although these developments important constructive, they have tended be framed terms transfer systems, knowledge, skills from relatively...