A5017800597- Antibiotic Use and Resistance
- Pharmaceutical Economics and Policy
- Pharmaceutical Practices and Patient Outcomes
- Medication Adherence and Compliance
- Blood Pressure and Hypertension Studies
- Patient Satisfaction in Healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Vaccine Coverage and Hesitancy
- Global Maternal and Child Health
- Glaucoma and retinal disorders
- Pharmaceutical studies and practices
- Retinal Imaging and Analysis
- SARS-CoV-2 and COVID-19 Research
- Healthcare Systems and Reforms
- Pharmacovigilance and Adverse Drug Reactions
- Retinal Diseases and Treatments
- HIV/AIDS Research and Interventions
- COVID-19 epidemiological studies
- Healthcare Systems and Technology
- Big Data Technologies and Applications
- Menopause: Health Impacts and Treatments
- Electroconvulsive Therapy Studies
- Human Mobility and Location-Based Analysis
- Pharmaceutical industry and healthcare
- Viral Infections and Outbreaks Research
Korle Bu Teaching Hospital
2014-2024
University of Ghana
2023
The Ohio State University
2018-2020
Pharmo Institute
2013-2017
Antimicrobial resistance (AMR) remains an important global public health issue with antimicrobial misuse and overuse being one of the main drivers. The Global Point Prevalence Survey (G-PPS) Consumption Resistance assesses prevalence quality prescriptions across hospitals globally. G-PPS was carried out at 17 Ghana, Uganda, Zambia Tanzania. overall use 50% (30–57%), most antibiotics prescribed belonging to WHO ‘Access’ ‘Watch’ categories. No ‘Reserve’ category study sites while...
The introduction of effective vaccines in December 2020 marked a significant step forward the global response to COVID-19. Given concerns with access, acceptability, and hesitancy across Africa, there is need describe current status vaccine uptake continent. An exploratory study was undertaken investigate these aspects, challenges, lessons learnt Africa provide future direction. Senior personnel 14 African countries completed self-administered questionnaire, descriptive analysis data....
Adherence to antiretroviral therapy (ART) is known be challenging among adolescents living with HIV/AIDS, notwithstanding the life-saving importance of this therapy. Of global total number HIV in 2013, 83% reside sub-Saharan Africa. The study aimed identify facilitators and barriers treatment adherence Ghana.A cross-sectional qualitative using semi-structured interviews for data collection was carried out (aged 12-19 years) at clinic Korle-Bu Teaching Hospital Ghana. Predominantly open-ended...
Childhood cancer is not a high priority in health care financing for many countries, including Ghana. Delayed seeking and treatment abandonment, often due to the financial burden of families, are common reasons relatively low overall survival (OS) low-and middle-income countries. In this study, we analyzed cost-effectiveness extending insurance coverage children with Burkitt lymphoma (BL) We developed Markov model Microsoft Excel estimate costs effects BL when National Health Insurance...
Assuring equitable universal access to essential health services without exposure undue financial hardship requires adequate resource mobilization, efficient use of resources, and attention quality responsiveness services. The way providers are paid is a critical part this process because it can create incentives patterns behaviour related supply. objective work was describe provider supply insured clients in Ghana the influence payment methods on behaviour. A mixed study involving grey...
Antimicrobial stewardship (AMS) initiatives promote the responsible use of antimicrobials in healthcare settings as a key measure to curb global threat antimicrobial resistance (AMR). Defining core elements AMS is essential for developing and evaluating comprehensive programmes. This project used co-creation Delphi consensus procedures adapt extend existing published international checklist. The overall objective was arrive at contextualised checklist behaviours within Sub-Saharan Africa,...
The World Health Organisation (WHO) and others have identified, as a priority, the need to improve antimicrobial stewardship (AMS) interventions part of effort tackle resistance (AMR). An international health partnership model, Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) programme, was established between selected countries in Africa (Ghana, Tanzania, Zambia Uganda) UK support AMS. This funded by aid under Fleming Fund managed Pharmacists Association (CPA) Tropical...
The first comprehensive point prevalence survey at the Korle Bu Teaching Hospital (KBTH) was performed as part of 2019 Global Point Prevalence Survey (Global-PPS) on antimicrobials. aim to establish a PPS baseline for whole hospital and identify required stewardship interventions. conducted over three days in June using GLOBAL-PPS standardized method surveillance antimicrobial utilization hospitals evaluate prescribing. In all, 988 patients were admitted 69 wards. Overall 53.3%. More...
Increasing trends in antimicrobial resistance among uropathogens call for rational use of empirical antibiotics managing uncomplicated urinary tract infections (UTIs). In Ghana, standard treatment guidelines (STGs) UTI recommend oral ciprofloxacin or cefuroxime 5–7 days females and 10–14 males. We conducted a cross-sectional audit using electronic medical records (EMR) to assess compliance the STGs adults (≥18 years) with UTIs diagnosed primary health facility between October 2019 2021....
many hypertensive patients require two or more anti-hypertensive drugs, but in low- and middle-income countries there may be challenges with medication access affordability. The objective of this study was to determine accessibility affordability medicines their association blood pressure (BP) control among attending the Korle-Bu teaching hospital (KBTH) polyclinic.a cross-sectional conducted 310 systematically sampled KBTH Polyclinic Ghana. A structured questionnaire used obtain data on...
Abstract Background Hypertensive and heart failure patients frequently require multiple drug therapy which may be associated with drug‐related problems (DRPs). Aim To determine the frequency, types, predictors of DRPs, acceptance pharmacists' interventions among hospitalized hypertensive patients. Method It was a prospective cross‐sectional study at internal medicine department wards Korle Bu Teaching Hospital (KBTH) between January June 2019 using validated form (the pharmaceutical care...
Abstract Objectives: The Women's Health Initiative (WHI) randomized trial identified age differences in the benefit-risk profile of estrogen-alone (ET) use. impact WHI on disease-associated medical expenditures attributable to subsequent decreased ET utilization has, however, not been measured. Therefore, objective this analysis was quantify age-specific reduced after Hormone Therapy (HT) trials. Methods: Population-level disease counts and associated between 2003 2015 were compared an...
Medicines, especially those that are packaged for the patient, by law required to include a set of information. This informs patient or client on his/her medication. Our aim was investigate factors associated with reading medicine/patient information leaflet among patients who advised read compared not, and find out whether there any significant differences between these two groups. A total 531 adult from main teaching hospital in Accra, Ghana, were asked fill questionnaire. Information...
Abstract Background: Antimicrobial stewardship (AMS) initiatives promote the responsible use of antimicrobials in healthcare settings as a key measure to curb global threat antimicrobial resistance (AMR). Defining core elements AMS is essential for developing and evaluating comprehensive programmes. This project used co-creation Delphi-consensus procedures adapt extend existing published international checklist. The overall objective was arrive at contextualised checklist behaviours within...
There is limited information on patterns of treatment change among new initiators highly active antiretroviral therapy (HAART) in the regions most affected by HIV/AIDS. This makes it difficult to identify determinants change. In this retrospective cohort study, we examined over a five-year period HAART. De-identified data were obtained from Fevers’ Unit Database at Korle-Bu Teaching Hospital. All adult treatment-naive patients who started with first line HAART between 1st January, 2008 and...
A customer’s perceived value of service has been identified as one the most important drivers satisfaction. Using a cross-sectional survey among out-patients with chronic disease in Ghana, this study assessed their perception on role hospital pharmacist, expectation services provided by pharmacist and factors encouraging them to speak pharmacist. This was during visits pharmacies at Korle-Bu Teaching Hospital. Six high patronage patients diseases were purposively selected. structured...
Background: Timely reporting of safety information post vaccination is pivotal for the success any program. Reports adverse events following immunization (AEFI) 6 different vaccinations from Ghana were analysed signals.Methods: De-identified data active surveillance AEFIs after 2009 AH1N1 influenza, yellow fever, meningitis, measles-rubella, pneumococcal-rotavirus and human papilloma virus used. All occurred between January 2010 December 2013. The ten most occurring each captured arranged...
Among the most vulnerable people in society are children and this is especially so their access to health care Off-label prescription of paediatric medicines known be associated with safety outcomes some which may serious. This study identifies frequently prescribed children's that not readily available Ghana prepared extemporaneously. All prescriptions for extemporaneous oral preparations presented local production unit Korle-Bu Teaching Hospital from November, 2013 were eligible study....
In many resource-constrained countries, control of blood pressure (BP) is low. Antihypertensive drug prescribing practices may influence BP control. However, adherence to treatment guidelines not be optimal in settings. The aim this study was evaluate the pattern pressure-lowering medication prescribing, and how it adheres guidelines, identify relationship between prescriptions
Extrapyramidal side effects of psychotropic medicines are usually experienced by patients in the first few weeks initiating therapy. Patients stabilized on these medications who present with distressing complaints akin to akathisia may be triggered other factors. This report presents two cases drug-drug-induced akathisia. Case A is a patient schizophrenia was being managed risperidone 2 mg tablet daily for past 3 years. She fell ill and reported nearby clinic where she prescribed...
<title>Abstract</title> Introduction Ward-based clinical pharmacy practice is now common in Ghana. The includes well-documented and published pharmacists’ interventions (PIs) to provide evidence of the activities pharmacists general. In an era limited resources, must demonstrate additional value services PIs improve quality health care outcomes. To determine economic impact PIs, various methods, tools, instruments are utilized. However, most these created utilized developed world, with a...