Julius Chacha Mwita

ORCID: 0000-0002-5947-3684
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About
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Research Areas
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Antibiotic Use and Resistance
  • Heart Failure Treatment and Management
  • Atrial Fibrillation Management and Outcomes
  • Infective Endocarditis Diagnosis and Management
  • Congenital Heart Disease Studies
  • Pharmaceutical Practices and Patient Outcomes
  • Lipoproteins and Cardiovascular Health
  • Streptococcal Infections and Treatments
  • HIV/AIDS Research and Interventions
  • HIV-related health complications and treatments
  • Venous Thromboembolism Diagnosis and Management
  • Patient Satisfaction in Healthcare
  • Otolaryngology and Infectious Diseases
  • Global Maternal and Child Health
  • Chronic Disease Management Strategies
  • Global Public Health Policies and Epidemiology
  • Blood Pressure and Hypertension Studies
  • Diabetes Treatment and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiovascular Health and Risk Factors
  • Surgical site infection prevention
  • Frailty in Older Adults
  • Diabetes Management and Research
  • Health Systems, Economic Evaluations, Quality of Life

University of Botswana
2016-2025

Invictus Medical (United States)
2024

Princess Margaret Hospital
2022

King Saud bin Abdulaziz University for Health Sciences
2021

Imam Mohammad ibn Saud Islamic University
2021

Stellenbosch University
2019-2020

University of Strathclyde
2019

Muhimbili University of Health and Allied Sciences
2010-2013

Introduction There are positive aspects regarding the prescribing of fixed dose combinations (FDCs) versus medicines separately. However, these have to be balanced against concerns including increased costs and their irrationality in some cases. Consequently, there is a need review value among lower- middle-income countries (LMICs) which greatest prevalence both infectious noninfectious diseases issues affordability.Areas covered Review potential advantages, disadvantages,...

10.1080/14737167.2020.1734456 article EN cc-by-nc-nd Expert Review of Pharmacoeconomics & Outcomes Research 2020-01-02

There are serious concerns with rising antimicrobial resistance (AMR) across countries increasing morbidity, mortality and costs. These have resulted in a plethora of initiatives globally nationally including national action plans (NAPs) to reduce AMR. Africa is no exception, especially the highest rates AMR globally. Key activities NAPs include gaining greater understanding current utilization patterns through point prevalence surveys (PPS) subsequently instigating stewardship programs...

10.3390/antibiotics11121824 article EN cc-by Antibiotics 2022-12-15

The introduction of effective vaccines in December 2020 marked a significant step forward the global response to COVID-19. Given concerns with access, acceptability, and hesitancy across Africa, there is need describe current status vaccine uptake continent. An exploratory study was undertaken investigate these aspects, challenges, lessons learnt Africa provide future direction. Senior personnel 14 African countries completed self-administered questionnaire, descriptive analysis data....

10.3390/vaccines10091553 article EN cc-by Vaccines 2022-09-17
Bo Daelman Liesbet Van Bulck Koen Luyckx Adrienne H. Kovacs Alexander Van De Bruaene and 95 more Magalie Ladouceur Hsiao‐Ling Yang Ju Ryoung Moon André Schmidt Birgitte Lykkeberg Edward Callus Michèle de Hosson Camilla Sandberg Bengt Johansson Joanna Hlebowicz Maria Emília Areias Pascal Amédro Louise Coats Zacharias Mandalenakis Anna Kaneva Philip Moons Eva Goossens Navaneetha Sasikumar Junko Enomoto Yoshiko Mizuno Ming Chern Leong Izzatun Nafsi Binto Sabran Laila Akbar Ladak Babar Hasan Ayat Siddiqui Ju Ryoung Moon June Huh Hsiao‐Ling Yang Jou‐Kou Wang Chun‐Wei Lu Fatma Demi̇r Korkmaz Tuğba Nur Öden Endale Tefera Julius Chacha Mwita Jean-Claude Ambassa Charles Mve Mvondo Marcel Fanka Dejuma Yadeta Mulualem Alemayehu Mohamed Lèye Khadija Gueye Harald Gabriel Matthias Svhneider Selina Seeliger Werner Budts Alexander Van De Bruaene Philip Moons Eva Goossens Liesbet Van Bulck Jessica Rassart Koen Luyckx Michèle de Hosson Julie De Backer Anna Kaneva M Marková Birgitte Lykkeberg Miriam Biyai Magalie Ladouceur Anissa Boubrit Jean‐Benoît Thambo Amandine Ruissel Cecile Jore Pascal Amédro Hamouda Abassi Sonia Soltani Charlène Bredy George Giannakoulas Diamantis Kosmidis Despina Ntiloudi Edward Callus Silvana Pagliuca Enrico Giuseppe Bertoldo Valentina Fiolo Maryanne Caruana J F Swain Neil Grech Rachel Anne Xuereb Sarah Craus John Bonello Darren Borg Paul Farrugia Joanne Cardona Mette‐Elise Estensen Brith Andresen Katrine Eriksen Maria Emília Areias Joana Miranda José Carlos Areias Cristina Cruz Filipe Macedo Filipa Nunes Ana Bessa Sara Mafalda Espírito Santo Paula Brito Marisa Pereira

10.1016/j.jacc.2024.01.021 article EN Journal of the American College of Cardiology 2024-03-01

Background: Multiple measures introduced early to restrict COVID-19 have dramatically impacted the teaching of medical and pharmacy students, exacerbated by lack infrastructure experience with e-learning at start pandemic. In addition, costs reliability Internet across Africa pose challenges alongside undertaking clinical practical programmes. Consequently, there is a need understand many how these were addressed, given increasingly complex patients, provide future direction. Method: An...

10.3390/healthcare9121722 article EN Healthcare 2021-12-13
Ganesan Karthikeyan Mpiko Ntsekhe Shofiqul Islam Sumathy Rangarajan Álvaro Avezum and 95 more Alexander P. Benz Tantchou Tchoumi Jacques Cabral Changsheng Ma Philly Chillo Jesús Antonio González-Hermosillo Bernard Gitura Albertino Damasceno Antonio Miguel L. Dans Kairat Davletov Alaa Elghamrawy Ahmed ElSayed Golden Tafadzwa Fana Lillian Gondwe Abraham Haileamlak Azhar Mahmood Kayani Peter Lwabi Fathi Maklady Onkabetse Julia Molefe-Baikai John Musuku Okechukwu S. Ogah María Paniagua Emmanuel Rusingiza Sanjeev Sharma Liesl Zühlke Stuart J. Connolly Salim Yusuf Monkgogi Goepamang Julius Chacha Mwita Auristela Isabel de Oliveira Ramos Flávio Tarasoutchi Milena Ribeiro Paixao Marcelo Kirschbaum Mariana Pezzute Lopes Walkíria Samuel Ávila Lília Nigro Maia Marcelo Arruda Nakazone Osana Costa Maria Carmen Lemos Lívia Costa de Oliveira Jose Ferreira José Francisco Kerr Saraiva Midia Costa Marina Marengo Óscar Pereira Dutra R.M. Guimarães Humberto Vaz Sergio Luiz Zimmerman Weimar Kunz Sebba Barroso Weimar Queiroz Adriana Ferreira de Souza Maria H Vidotti Jose Guilherme de Paula Guilherme Fazolli Mauro Esteves Hernandes Jose Luiz Torati Grazielly Pantano Vanessa Pelarin Flavia Arantes Rodrigo Otávio Silveira Silva Monique Cardoso Gilmar Reis César França Túlio Fonseca e Silva Quadros Flavio Giorgeto Resende Elmiro Silva Aguinaldo César Minelli Helen Mbuoh Anshoma Jean Claude Ambassa Liliane Mfevkev Kuate Chris Nadege Nganou Gninotio Ngo Youmba Ntep Gweth Dzudie Anastase D. Armel Lionel Nana Keptukoua Xin Du Rong Hu Jiahui Wu Qiang Lv Jing Cui Qing Yu Xudong Zhu Wei Su Xiaomei Wang Shiyi Chen Zhipeng Zhang Qi Wang Xin Zheng Pengfei Liu Cheng Rang Sitao Xie Chongwen Liu Hailong Wang Shudong Wang Xuxia Zhang

Rheumatic heart disease (RHD) remains a public health issue in low- and middle-income countries (LMICs). However, there are few large studies enrolling individuals from multiple endemic countries.

10.1001/jama.2024.8258 article EN JAMA 2024-06-05

Antibiotic prophylaxis in surgery is known to reduce the rate of surgical site infections (SSI) as well shorten hospital stay. However, there currently a scarcity data on antibiotic and SSIs among African countries including Botswana. Consequently, this study aimed address this.A prospective involving 400 patients was carried out at leading tertiary Botswana from 2014-2015. Patients' demographic information, type performed peri-operative use antibiotics were documented. All enrolled...

10.1080/21548331.2018.1450605 article EN Hospital Practice 2018-03-09

Currently about 19 million people in Africa are known to be living with diabetes, mainly Type 2 diabetes (T2DM) (95%), estimated grow 47 by 2045. However, there concerns early diagnosis of patients 1 (T1DM) as often present late complications. There also challenges access and affordability insulin, monitoring equipment test strips typically high patient co-payments, which can catastrophic for families. These negatively impact on the quality care T1DM increasing morbidity mortality. issues...

10.1080/21548331.2020.1745509 article EN Hospital Practice 2020-03-14

Warfarin treatment requires regular and proper monitoring to avoid overanticoagulation at the same time prevent thromboembolic complications. This study assessed quality of warfarin anticoagulation Princess Marina Hospital in Botswana. cross-sectional consecutively enrolled patients who were on for least 3 months outpatient medical clinic. The level was determined by therapeutic range (TTR) using Rosendaal method that calculates percentage days when international normalized ratio is...

10.1177/1076029617747413 article EN cc-by-nc Clinical and Applied Thrombosis/Hemostasis 2017-12-19

Abstract Background Asthma is a common chronic disease of childhood that associated with significant morbidity and mortality. We aimed to estimate the prevalence asthma among secondary school pupils in urban rural areas coast districts Tanzania. The study also describe pupils’ perception towards asthma, assess their knowledge on symptoms, triggers, treatment asthma. Methods A total 610 from Ilala district 619 Bagamoyo formed groups, respectively. Using modified International Study Allergies...

10.1186/1471-2458-14-387 article EN cc-by BMC Public Health 2014-04-23

This was a cross-sectional study designed to assess the validity of Finnish Diabetes Risk Score for detecting undiagnosed type 2 diabetes among general medical outpatients in Botswana. Participants aged ≥20 years without previously diagnosed were screened by (1) an 8-item risk assessment questionnaire and (2) Haemoglobin A1c test. Data from 291 participants analyzed (74.2% females). The mean age 50.1 (SD = ±11) years, prevalence 42 (14.4%) with no significant differences between gender (20%...

10.1155/2016/4968350 article EN cc-by Journal of Diabetes Research 2016-01-01

Heart failure is a common cause of hospitalisation and therefore contributes to in-hospital outcomes such as mortality. In this study we describe patient characteristics acute heart (AHF) in Botswana.

10.5830/cvja-2016-067 article EN Cardiovascular journal of South Africa/Cardiovascular journal of Southern Africa 2017-04-20

Control of glycaemic, hypertension and low-density lipoprotein-cholesterol (LDL-C) among patients with type 2 diabetes mellitus (T2DM) is vital for the prevention cardiovascular diseases. The current study was an audit LDL-C control ambulant T2DM in Botswana. Also, aimed at assessing factors associated attaining optimal therapeutic goals.A cross-sectional study.A specialised public clinic Gaborone, Botswana.Patients who had attended ≥3 months between August 2017 February 2018.The proportion...

10.1136/bmjopen-2018-026807 article EN cc-by-nc BMJ Open 2019-07-01

There is evidence of statin benefit among patients with diabetes regardless cholesterol levels or prior cardiovascular disease history. Despite the evidence, there under-prescription statins in clinical practice. This study aimed to assess prescriptions and associated factors type 2 Botswana.The was a secondary data analysis 500 randomly selected at specialised clinic Gaborone, Botswana. We assessed proportion statin-eligible who are prescribed evaluated adjusted associations between various...

10.1186/s12902-020-0516-7 article EN cc-by BMC Endocrine Disorders 2020-03-10
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