Adesola Yinka-Ogunleye

ORCID: 0000-0003-0900-4772
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About
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Research Areas
  • Poxvirus research and outbreaks
  • Bacillus and Francisella bacterial research
  • Herpesvirus Infections and Treatments
  • Viral Infections and Outbreaks Research
  • COVID-19 epidemiological studies
  • Zoonotic diseases and public health
  • Global Maternal and Child Health
  • COVID-19 Clinical Research Studies
  • Global Health Care Issues
  • Healthcare Systems and Reforms
  • Pneumonia and Respiratory Infections
  • Antibiotic Use and Resistance
  • COVID-19 Pandemic Impacts
  • Bacteriophages and microbial interactions
  • Data-Driven Disease Surveillance
  • SARS-CoV-2 and COVID-19 Research
  • Disaster Response and Management
  • Pharmaceutical Practices and Patient Outcomes
  • COVID-19 and healthcare impacts
  • Vaccine Coverage and Hesitancy
  • Virology and Viral Diseases
  • Misinformation and Its Impacts
  • Plant Virus Research Studies

Nigeria Centre for Disease Control
2018-2023

University College London
2021-2023

World Health Organization
2023

National Veterinary Research Institute
2023

Federal Ministry of Agriculture and Rural Development
2023

Centers for Disease Control and Prevention
2018-2023

Helmholtz Centre for Infection Research
2020

German Center for Infection Research
2020

Institut Pasteur de Dakar
2018

Redeemer's University
2018

In a retrospective review of hospital records 40 human monkeypox cases from Nigeria, the majority developed fever and self-limiting vesiculopustular skin eruptions. Five deaths were reported. Compared to immunodeficiency virus (HIV)-negative cases, HIV type 1-coinfected had more prolonged illness, larger lesions, higher rates both secondary bacterial infections genital ulcers.

10.1093/cid/ciaa143 article EN Clinical Infectious Diseases 2020-02-11

The largest West African monkeypox outbreak began September 2017, in Nigeria. Four individuals traveling from Nigeria to the United Kingdom (n = 2), Israel 1), and Singapore 1) became first human cases exported Africa, a related nosocomial transmission event confirmed human-to-human outside of Africa.Epidemiological molecular data for Nigerian were analyzed jointly better understand exportations temporal geographic context outbreak.Isolates all travelers Bayelsa case shared most recent...

10.1093/infdis/jiaa559 article EN cc-by-nc-nd The Journal of Infectious Diseases 2020-08-29

Monkeypox (mpox) is a zoonotic disease caused by virus (MPXV), an Orthopoxvirus; the wild mammalian reservoir species not known. There are two genetic clades of MPXV: clade I and II (historically found in central west Africa, respectively), with only Cameroon reporting both (1). Human cases have historically been reported from 1) mostly rural, forested areas some African countries; 2) countries related to population migration or travel infected persons; 3) exposure imported mammals (2). The...

10.15585/mmwr.mm7203a4 article EN MMWR Morbidity and Mortality Weekly Report 2023-01-19

The 2022 global mpox outbreak raises questions about how this zoonotic disease established effective human-to-human transmission and its potential for further adaptation. virus is related to an ongoing in Nigeria originally reported 2017, but the evolutionary path linking two remains unclear due a lack of genomic data between 2018, when exportations from were first recorded, 2022, began. Here, 18 viral genomes obtained patients across southern 2019-2020 reveal multiple lineages monkeypox...

10.1038/s41591-023-02456-8 article EN cc-by Nature Medicine 2023-09-01

Background: Human monkeypox (HMPX) is currently spreading outside endemic countries in Africa and the majority of those affected are gay bisexual men within interconnected sexual networks. We investigated history HMPX cases seen at a tertiary hospital Bayelsa State during 2017-2018 outbreak Nigeria.Method: A cross-sectional study was conducted between 20 October 2017 2 January 2019 among adult confirmed/probable cases. questionnaire used to collect data on participants, including contact...

10.1177/09564624221119335 article EN International Journal of STD & AIDS 2022-08-15

The introduction of effective vaccines in December 2020 marked a significant step forward the global response to COVID-19. Given concerns with access, acceptability, and hesitancy across Africa, there is need describe current status vaccine uptake continent. An exploratory study was undertaken investigate these aspects, challenges, lessons learnt Africa provide future direction. Senior personnel 14 African countries completed self-administered questionnaire, descriptive analysis data....

10.3390/vaccines10091553 article EN cc-by Vaccines 2022-09-17

We report a case of suicide in 34-year-old businessman who was admitted to an isolation facility tertiary hospital during the 2017/2018 monkeypox outbreak Nigeria. describe possible psychosocial factors associated with and highlight challenges faced lessons learnt management case. To our knowledge, this is first reported linked human monkeypox.

10.1016/j.ijregi.2022.04.004 article EN cc-by-nc-nd IJID Regions 2022-04-26

Introduction Recent outbreaks of mpox are characterised by changes in the natural history disease, demographic and clinical characteristics cases, widening geographical distribution. We investigated role HIV other sexually transmitted infections (STIs) coinfection among cases re-emergence to inform national global response. Methods conducted a descriptive case–control study on 2017–2019 Nigerian outbreak. Mpox were age, sex area matched each with two randomly selected controls from...

10.1136/bmjgh-2023-013126 article EN cc-by-nc-nd BMJ Global Health 2023-11-01

The problem of antimicrobial resistance (AMR) has assumed pandemic dimensions especially among low-and middle-income countries such as Nigeria. Irrational use currently available agents is a major contributory factor. There remains paucity documented information on the determinants antibiotic prescribing physicians in Nigeria to guide future strategies reduce AMR. This study therefore aimed investigate patterns and doctors tertiary hospital first step improve hospitals.A cross-sectional...

10.1080/21548331.2018.1475997 article EN Hospital Practice 2018-05-14

The objective of this study was to describe the epidemiology COVID-19 in Nigeria with a view generating evidence enhance planning and response strategies. A national surveillance dataset between 27 February 6 June 2020 retrospectively analysed, confirmatory testing for done by real-time polymerase chain reaction (RT-PCR). primary outcomes were cumulative incidence (CI) case fatality (CF). total 40 926 persons (67% 60 839) had complete records RT-PCR test across 35 states Federal Capital...

10.1017/s095026882000206x article EN cc-by-nc-nd Epidemiology and Infection 2020-01-01

In November 2017, the mobile digital Surveillance Outbreak Response Management and Analysis System was deployed in 30 districts Nigeria response to an outbreak of monkeypox. Adaptation activation system took 14 days, its use improved timeliness, completeness, overall capacity response.

10.3201/eid2602.191139 article EN cc-by Emerging infectious diseases 2020-01-07

In September 2018, the first case of an outbreak monkeypox was reported in Nigeria, which likely resulted from a complex intersection events and required robust response collaboration among human, animal, environmental health institutions.

10.15585/mmwr.mm6737a5 article EN MMWR Morbidity and Mortality Weekly Report 2018-09-20

The understanding of antimicrobial utilization patterns is pertinent to successful implementation the National Action Plans on Antimicrobial Resistance (AMR). There is, however, limited information antibiotics in Nigeria. This study was undertaken build existing and provide direction for appropriate interventions including Antibiotics Stewardship Programs (ASP).A Point Prevalence Study (PPS) conducted two public urban health facilities Lagos, Nigeria using a design adapted from European...

10.1080/14787210.2021.1941870 article EN Expert Review of Anti-infective Therapy 2021-06-15

Sub-Saharan Africa (SSA) is disproportionately affected by mpox and HIV. We described epidemiologic trends clinical experiences in the management of people living with HIV (PLWH) Nigeria further examined how rapidly accumulating body knowledge from 2022 global outbreak might be explored to improve care PLWH SSA. During 2017/2018 Nigerian outbreak, we reported that 9/40 (22.5%) hospitalized patients known status were PLWH. In 52% confirmed cases PLWH, predominantly sexual gender minority...

10.1089/aid.2023.0034 article EN AIDS Research and Human Retroviruses 2023-08-30
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