A5057039285- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Machine Learning in Bioinformatics
- Mercury impact and mitigation studies
- Antimicrobial Peptides and Activities
- Venomous Animal Envenomation and Studies
- Mosquito-borne diseases and control
- Evolution and Genetic Dynamics
- Genetically Modified Organisms Research
- Bioactive Compounds in Plants
- Pluripotent Stem Cells Research
- Plant tissue culture and regeneration
- Influenza Virus Research Studies
- Vibrio bacteria research studies
- Transgenic Plants and Applications
- COVID-19 Prevention and Impact
- Urinary Tract Infections Management
- Viral Infections and Vectors
- Antibiotic Resistance in Bacteria
- Computational Drug Discovery Methods
- Enterobacteriaceae and Cronobacter Research
- Isotope Analysis in Ecology
- Microplastics and Plastic Pollution
- vaccines and immunoinformatics approaches
Universitas Gadjah Mada
2021-2024
Kobe University
2017-2019
ASEAN (Association of Southeast Asian Nations) is composed ten countries bound by socio-cultural ties that promote regional peace and stability. South Asia, located in the southern subregion includes nine sharing similarities geographical ethno-cultural factors. Chikungunya one most significant problems countries. Much current chikungunya epidemic Asia caused emergence a virus strain originated Africa spread to Asia. Meanwhile, three confirmed lineages are circulation. Given positive...
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Snake envenomation is a severe economic and health concern affecting countries worldwide. venom carries wide variety of small peptides proteins with various immunological pharmacological properties. A few key research areas related to snake venom, including its applications in treating cancer eradicating antibiotic-resistant bacteria, have been gaining significant attention recent years. The goal the current study was analyze global profile literature research. This presents bibliometric...
This study aimed to determine the prevalence of multidrug-resistant (MDR) bacterial isolates in urinary tract infections (UTI) patients Indonesia, where access appropriate antibiotic treatment may be limited. A cross-sectional was conducted from January 2020 December 2022, with 308 UTIs cultured and tested for antimicrobial susceptibility. The most identified isolate Escherichia coli (39.6 %), followed by Klebsiella pneumoniae (11.6 %) Staphylococcus spp. (11.03 %). overall MDR 35 %, highest...
Alzheimer's disease (AD) is the most known neurodegenerative disease, and its prevalence predicted to increase significantly. Discovering novel drugs treatments for AD urgently needed. Drugs from natural products have been preferred lately due their high potential low toxicity. Citrus hystrix DC. (kaffir lime; KL) one such herbal plant that found abundantly in Southeast Asia with many biological activities. In this study, of bioactive compounds KL peel, leaf, essential oil as anti-AD agents...
Occult hepatitis B infection (OBI) is defined as the presence of virus (HBV) DNA in serum and/or liver HBsAg-negative individuals. OBI associated with risk viral transmission, especially developing countries, and progressive disease reactivation immunosuppressive patients. The objective this study was to evaluate relation HLA-DP single nucleotide polymorphisms (SNPs) encoding antigen-binding sites for immune response HBV infection. As variants affect mRNA expression HLA-DPA1 HLA-DPB1 liver,...
Abstract Indonesia is well-known for having a vast and rich endowment of unique genetically diverse biodiversity resources. Currently, initiatives are taking place around the world to generate DNA barcode libraries make these data available better understand biodiversity. The objectives this study document research trends detect extent which its application has evolved in Indonesia. analysis was investigated using compilation 446 published papers, obtained from Harzing's Publish or Perish 8....
OBJECTIVES: This study aimed to analyze the global profi le of literature in non-alcoholic fatty liver disease (NAFLD) research.BACKGROUND: Non-alcoholic is a clinically heterogeneous condition characterized by fat accumulation and absence signifi cant alcohol consumption or underlying genetic disorders.These manifestations are associated with infl ammation, steatosis, fi brosis that can develop into cirrhosis even hepatocellular carcinoma.However, about research trend NAFLD has never been...
Hepatitis B virus (HBV) polymerase gene is targeted by nucleos(t)ide analogues (NUC), but it unclear how HBV quasispecies of whole genome changes during early period NUC treatment. To understand the unknown region drug sensitivity and treatment resistance, was examined using ultra‑deep sequencing. Eleven patients with chronic infection who received were enrolled in current study. Viral DNA extracted from serum samples before Polymerase chain reaction analysis subsequently performed on...
Abstract. Rahayu HM, Putri WA, Khasanah AU, Sembiring L, Purwestri YA. 2021. Indigenous Streptomyces spp. isolated from Cyperus rotundus rhizosphere indicate high mercuric reductase activity as a potential bioremediation agent. Biodiversitas 22: 1519-1526. The purification and characterization of four indigenous L. in mercury-contaminated area have been investigated. Cell-free extract was obtained by disrupting cells using sea sand at 4 °C followed centrifugation. Mercuric purified ammonium...
Aim: This study aimed to evaluate the trends in organoid culture research within field of regenerative medicine from 2002 2022. Methods: The worldwide distribution articles indexed Scopus database was analyzed. Result: A total 840 documents were analyzed, averaging 42 publications annually. USA (n = 296) led publications, followed by China 127), Japan 91) and UK 75). Since 2011, has surged, particularly China, which emerged as a prominent center. Conclusion: findings highlight significant...
Objectives: This study aimed to analyze the global profile of nucleotide/nucleoside analogs (NAs) for chronic hepatitis virus therapy-related research. Background: NAs, which closely resemble structure naturally occurring nucleotides/nucleosides, function by disrupting elongation nascent DNA strand. These compounds are considered safe and well-tolerated, as they specifically target viral, but not human, polymerases involved in replication. NAs crucial treating viral infections, including...
The natural ingredient-based therapy extracted from various plants is assumed more tolerable to cancer patients’ bodies than synthetic drugs. To tell successful novel therapy, an indicator needed confirm the result. VEGF a pro-angiogenic factor that leads cells’ invasion another organ and associated with high mortality in patients. Hence, level widely used as one of indicators. Purposed research elucidated effect Mandarin orange peel ethanol extract (EEKJM) improve reduction levels colon...
Antiviral peptides (AVPs) are small molecules that inhibit the replication of viruses in living cells. AVPs being investigated as potential alternatives to traditional antiviral drugs. The development novel agents is highest concern because some medications can be ineffective and lead resistant emergence. We conducted a bibliometric study on global distribution AVP research comprehend trends patterns field. For this analysis, we retrieved data from Scopus database AVP-related publications...
Hepatitis B Virus (HBV) is an endemic virus and belongs to Hepadnaviridae family. This can result in variations of quasispecies due its high rate mutation. A variant a small population develops as mutation become wild-type population. research aims study carry out 3D modeling on 12 in-house full sequence HBV genome isolates from Indonesia obtain predictive visualization data reference for further leading the production anti-virals natural treatments HBV. sequences obtained previous were used...
Mercury pollution poses a significant environmental challenge worldwide, prompting extensive efforts over the past two decades to combat its detrimental effects. Cloning merA from Streptomyces sp. AS2 (Accession numbers LC026157) into expression vector pET-28c (+) marks critical advancement in this field, necessitating further investigation and structural analysis of resulting recombinant mercuric reductase protein. This study aimed optimise characterise MerA The involved isolate host...
Abstrak: Budidaya ikan nila di sawah (minapadi) merupakan potensi utama yang diangkat oleh desa wisata Kebonagung. Akan tetapi, tingginya harga pakan menjadi kendala dihadapi warga dalam pengembangan minapadi. Pakan berbasis maggot alternatif murah dengan kualitas nutrisi tinggi. Program pengabdian ini bertujuan untuk memberikan pemahaman dan keterampilan pembuatan dari dilaksanakan bersama Karang Taruna Tani Rukun Santoso Kelompok Wanita (KWT) Sekar Arum, Kebonagung, Imogiri, Bantul,...
Mutations in the hepatitis B virus (HBV) X region and truncation of preS2 are well‑known to affect progression liver disease. Recently, it has been observed that an increasing number S quasispecies variants associated with disease progression. However, few studies have analysed whole genome using high‑throughput sequencing methods. Using sequencing, whole‑genome variations 12 Indonesian patients infected HBV (eight advanced four chronic hepatitis) were examined. Variations cut‑off values ≥1%...
Abstract: The e-Bintech 5.0 online workshop was held to sharpen the concept of village that is a multidisciplinary acculturation-constellation. In this workshop, multiplatform frameworks were successfully formulated as basic guideline for developments towards glory Indonesia. Pentahelix platform synergy needed (academics, business, government, community, media) supported by relevant stakeholders fostering futuristic creation Indonesia 5.0, especially in terms ease investment, simplification...
Abstract Efforts to control mercury pollution have been made for the last twenty years using various biological, physical, and chemical approaches. Streptomyces is able degrade because it possesses mercuric reductase enzyme encoded by mer A. The A from isolate AS2 ( Accession numbers LC026157) has cloned into expression vector pEt-28c(+). Therefore, critical study recombinant protein's analyse protein structure. Expression of an was successfully performed in host Escherichia coli BL21....
Streptomyces is one of mercury‐resistant bacteria which can convert Hg2+ into nontoxic Hg0 . This study aimed to identify present in the Cyperus rotundus rhizosphere from artisanal small‐scale gold mining (ASGM) area and clone merA gene cloning expression vectors. Molecular identification was conducted using 16s rRNA with maximum likelihood algorithms. Results revealed that AS1 AS2 strains were a group ardesiacus BR28 strain closed Brevibacillus agri. The cloned pMD20 vectors, pGEX‐5x‐1...