A5027002141- Cancer-related molecular mechanisms research
- MicroRNA in disease regulation
- Circular RNAs in diseases
- Steroid Chemistry and Biochemistry
- Viral Infections and Vectors
- Cholesterol and Lipid Metabolism
- Mosquito-borne diseases and control
- Protein Degradation and Inhibitors
- Prostate Cancer Treatment and Research
- Hormonal Regulation and Hypertension
- Cancer, Lipids, and Metabolism
- Histone Deacetylase Inhibitors Research
- Peptidase Inhibition and Analysis
Birla Institute of Technology and Science - Hyderabad Campus
2021-2023
Birla Institute of Technology and Science, Pilani
2021-2023
Christian Medical College & Hospital
2015
Transforming growth factor beta (TGF-β)-regulated long-non-coding RNAs (lncRNAs) modulate several aspects of tumor development such as proliferation, invasion, metastasis, epithelial to mesenchymal transition (EMT), and drug resistance in various cancers, including Glioblastoma multiforme (GBM). We identified novel differentially expressed lncRNAs upon TGF-β treatment glioma cells using genome-wide microarray screening. show that induces lncRNA-MUF cells, its expression is significantly...
Prostate cancer (PCa) is the most common malignancy in men. Despite aggressive therapy involving surgery and hormonal treatments, recurrence emergence of metastatic castration-resistant prostate (CRPCa) remain a major challenge. Dysregulation transforming growth factor-β
Cerebrotendinous xanthomatosis is a lipid storage disease characterized by diarrhea, cataract, tendon xanthoma and neurological regression if untreated. CYP27A1 the only gene in which mutations are known to cause xanthomatosis. We report two Indian families from different regions of India who underwent molecular testing CYP27A1. The first family Eastern consisting affected individuals was found have c.526delG homozygous mutation exon 3, previously reported our laboratory, also patient India....
ABSTRACT Infection of the central nervous system by Japanese encephalitis virus (JEV) is characterized extensive neuronal cell death and neuroinflammation. Several protein-coding genes microRNAs are implicated in JEV-induced death. However, global expression patterns functional contributions long non-coding RNAs (lncRNAs) during have not been explored. Here, we profiled transcriptome JEV-infected line identified several lncRNAs whose altered JEV infection. We functionally a lncRNA named...