A5063247962- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Inflammatory Biomarkers in Disease Prognosis
- Cardiovascular Health and Disease Prevention
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Medical Imaging Techniques and Applications
- Venous Thromboembolism Diagnosis and Management
- Advanced X-ray and CT Imaging
- Cardiovascular Disease and Adiposity
- Coronary Artery Anomalies
- Health Systems, Economic Evaluations, Quality of Life
- Biomarkers in Disease Mechanisms
- Congenital Heart Disease Studies
- Renal and Vascular Pathologies
- Cerebrovascular and Carotid Artery Diseases
- Blood properties and coagulation
- Pulmonary Hypertension Research and Treatments
- Cardiac Valve Diseases and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrhythmias and Treatments
- Atherosclerosis and Cardiovascular Diseases
Medical University of Silesia
2015-2024
Silesian Center for Heart Disease
2014-2024
Górnośląskie Centrum Medyczne
2001-2016
Queen Elizabeth II Health Sciences Centre
2014
Dalhousie University
2014
Sterling Hospitals
2014
Duke Medical Center
2014
Clinical Research Institute
2014
National Heart Lung and Blood Institute
2014
All India Institute of Medical Sciences
2014
Data regarding the association between red cell distribution width (RDW) values and mortality in patients with stable coronary artery disease are scarce. We aimed to investigate link RDW undergoing percutaneous intervention (PCI). analyzed 2550 consecutive who underwent PCI 2007 2011 at our institution. The were divided into four groups according quartiles. outcomes was assessed using Cox proportional regression analysis after adjusting for clinical, echocardiographic, hemodynamic laboratory...
The STICH (Surgical Treatment for Ischemic Heart Failure) trial compared a strategy of routine coronary artery bypass grafting (CABG) with guideline-based medical therapy patients ischemic left ventricular dysfunction.To describe treatment-related quality-of-life (QOL) outcomes, major prespecified secondary end point in the trial.Randomized trial. (ClinicalTrials.gov: NCT00023595).99 clinical sites 22 countries.1212 ejection fraction 0.35 or less and disease.Random assignment to alone (602...
Mean platelet volume (MPV) is a simple and reliable indicator of size that correlates with activation their ability to aggregate. We studied the predictive value MPV in patients non-ST-segment elevation myocardial infarction (NSTEMI) treated percutaneous coronary intervention (PCI).We analyzed consecutive records 1001 who were hospitalized due NSTEMI at our center. The primary end point was composite included rates all-cause death, non-fatal infarction, acute syndrome (ACS) driven...
There is no data regarding the association between platelet-to-lymphocyte ratio (PLR) and long-term mortality in patients with stable coronary artery disease (SCAD). The aim of this study to evaluate utility pre-procedural PLR for predicting long-term, all-cause SCAD undergoing percutaneous intervention (PCI) stent implantation.We analyzed a total 2959 consecutive who underwent PCI (balloon angioplasty followed by implantation or direct stenting) July 2006 December 2011 at our institution....
Background Neointima forming after stent implantation consists of vascular smooth muscle cells (VSMCs) in 90%. Growth factors TGF-β1, PDGFB, EGF, bFGF and VEGF-A play an important role VSMC proliferation migration to the tunica intima arterial wall injury. The aim this paper was analysis functional polymorphisms genes encoding relation in-stent restenosis (ISR). Materials Methods 265 patients with a stable coronary artery disease (SCAD) hospitalized our center years 2007–2011 were included...
POLSKIE ARCHIWUM MEDYCYNY
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Wasilewski J, Niedziela Osadnik T, et al. Predominant location of coronary artery atherosclerosis in the left anterior descending artery. The impact septal perforators and myocardial bridging effect. Kardiochirurgia i Torakochirurgia Polska/Polish Journal Thoracic Cardiovascular Surgery. 2015;12(4):379-385. doi:10.5114/kitp.2015.56795. APA Wasilewski, J., Niedziela, Osadnik, T., Duszańska, A., Sraga, W., &...
Abstract Due to the difficulties in retrieving both time-dependent shapes of vessels and generation numerical meshes for such cases, most simulations blood flow cardiac arteries use static geometry. The article describes a methodology generating sequence 3D based on images different resolutions qualities acquired from ECG-gated coronary artery CT angiography. precision shape restoration method has been validated using an independent technique. original proposed approach also generates each...
Despite the important roles of vascular smooth muscle cells and endothelial in atherosclerotic lesion formation, data regarding associations functional polymorphisms genes encoding growth factors with severity coronary artery disease (CAD) are lacking. The aim present study is to analyze relationships between basic fibroblast factor (bFGF, FGF2), epidermal (EGF), insulin-like factor-1 (IGF-1), platelet derived factor-B (PDGFB), transforming factor-β1 (TGF-β1) A (VEGF-A) atherosclerosis...
Platelets represent an important link between inflammation and thrombosis play role in all stages of atherosclerotic lesion formation. Increased platelet activity their tendency to clot formation favour the incidence thrombotic complications, such as unstable angina pectoris (UA), myocardial infarction (MI) sudden cardiac death, course coronary artery disease (CAD). Mean volume (MPV) reflects average size platelets and, under normal circumstances, ranges 7.5 fL 10.5 fL. Platelet-large cell...
It has been suggested that a wider left main (LM) bifurcation angle is associated with the development of atherosclerosis. However, relationship between LM trifurcation angulation and atherosclerosis not investigated.We aimed to investigate presence calcifications in coronary artery (LCA) using computed tomography angiography (CCTA). Furthermore, we assessed age at which calcification originated.The calcium (CAC) score LCA were measured. Based on observational studies, assumed CAC...
Abstract Blood flow is most often modeled in vessels whose shape does not change over time. This approach significantly simplifies the calculations and reduces their Temporal vascular deformations affect blood patterns, deposition of atherosclerotic plaques, formation aneurysms, many other phenomena. There are two methods to consider vessel deformations: registration geometry by diagnostic imaging such as CT, MRI, ultrasound or use fluid-structure interaction (FSI) models. The first method...
Aim: To analyze the association between in-stent restenosis (ISR) and polymorphisms in genes coding IGF-1, IGFBP3, ITGB3 GLUT1, which play an important role smooth muscle cell proliferation extracellular matrix synthesis – main components of neointima. Materials & methods: We analyzed 265 patients who underwent bare metal stent implantation. Results: The differences occurrence ISR genotypes IGFBP3 were not statistically significant. T/T genotype rs710218 polymorphism GLUT1 (SLC2A1) gene was...
Randomized controlled trials are the gold standard for evaluating therapy; however, controversy exists regarding applicability of such results to daily practice, as patients often pre-selected and may not reflect real-world clinical settings. We studied eligibility criteria 3102 “real-life” with stable coronary artery disease (SCAD) according ISCHEMIA (International Study Comparative Health Effectiveness Medical Invasive Approaches) trial exclusion criteria. The aim our analysis was estimate...