A5032721406- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Radiation Therapy and Dosimetry
- Advanced X-ray and CT Imaging
- Advanced Radiotherapy Techniques
- Radiation Detection and Scintillator Technologies
- Medical Image Segmentation Techniques
- Scientific Computing and Data Management
- Gene Regulatory Network Analysis
- Evolution and Genetic Dynamics
- Advanced MRI Techniques and Applications
- AI in cancer detection
- Mathematical Biology Tumor Growth
- Lung Cancer Diagnosis and Treatment
- MRI in cancer diagnosis
- Bioinformatics and Genomic Networks
- Radiation Dose and Imaging
- Gene expression and cancer classification
- Mathematical and Theoretical Epidemiology and Ecology Models
- Data Visualization and Analytics
- Computer Graphics and Visualization Techniques
- Protein Structure and Dynamics
- Reservoir Engineering and Simulation Methods
- Nuclear Physics and Applications
- Cancer, Hypoxia, and Metabolism
Silesian University of Technology
2016-2025
Institute of Nuclear Physics, Polish Academy of Sciences
2022-2024
The Maria Sklodowska-Curie National Research Institute of Oncology
2019-2023
University of Vienna
2023
Radiopharmaceutical dosimetry depends on the localization in space and time of radioactive sources requires estimation amount energy emitted by deposited within targets. In particular, when computing resources are not accessible, this task can be performed using precomputed tables specific absorbed fractions (SAFs) or S values based dosimetric models. The aim OpenDose collaboration is to generate make freely available a range data tools. <b>Methods:</b> brings together expertise from 18...
Our goal was to determine the influence of sex, age and head/brain size on compartmental brain volumes in radiologically verified healthy population (96 subjects; 54 women 42 men) from Upper Silesia region Poland. The MRI examinations were done using 3T Philips Achieva with same T1-weighted T2-weighted protocols. image segmentation procedures performed SPM (Statistical Parameter Mapping) FSL-FIRST software. 14 subcortical structures for left right hemispheres 4 overall calculated. General...
To study the effect of dose-rate in time evolution chemical yields produced pure water versus a cellular-like environment for FLASH radiotherapy research. 
A version TOPAS-nBio with Tau-Leaping algorithm was used to simulate homogenous chemistry stage radiolysis using three models: 1) liquid model that considered scavenging eaq-, H● by dissolved oxygen; 2) Michaels & Hunt ●OH, and biomolecules existing cellular environment; 3) Wardman repair enzyme glutathione (GHS). H2O2 concentrations...
The Jagiellonian PET (J-PET) technology, based on plastic scintillators, has been proposed as a cost effective tool for detecting range deviations during proton therapy. This study investigates the feasibility of using J-PET monitoring by means detailed Monte Carlo simulation 95 patients who underwent therapy at Cyclotron Centre Bronowice (CCB) in Krakow, Poland. 
Approach: Discrepancies between prescribed and delivered treatments were artificially introduced simulations shifts patient...
Live-cell fluorescence image segmentation is an essential step in many studies, including drug research and other contexts where keeping cells alive crucial. Several algorithms programs have been previously proposed; however, they do not work sufficiently well on top-down pictures with overlapping cells. Our proposed algorithm, called GRABaCELL, utilizes Graph Cut, Watershed Hough Circular Transform to improve automatic counting living We also introduce a modified accuracy metric determine...
Abstract Due to the difficulties in retrieving both time-dependent shapes of vessels and generation numerical meshes for such cases, most simulations blood flow cardiac arteries use static geometry. The article describes a methodology generating sequence 3D based on images different resolutions qualities acquired from ECG-gated coronary artery CT angiography. precision shape restoration method has been validated using an independent technique. original proposed approach also generates each...
Abstract Background Tumour hypoxia is a recognised cause of radiotherapy treatment resistance in head and neck squamous cell carcinoma (HNSCC). Current positron emission tomography-based imaging techniques are not routinely available many centres. We investigated if an alternative technique called oxygen-enhanced magnetic resonance (OE-MRI) could be performed HNSCC. Methods A volumetric OE-MRI protocol for dynamic T1 relaxation time mapping was implemented on 1.5-T clinical scanners....
This paper reports on the implementation and shows examples of use ProTheRaMon framework for simulating delivery proton therapy treatment plans range monitoring using positron emission tomography (PET). offers complete processing plans, patient CT geometries, intra-treatment PET imaging, taking into account imaging coordinate systems activity decay during protocol specific to a given facility. We present illustrate its potential case data steps treated at Cyclotron Centre Bronowice (CCB)...
According to recent studies, breast cancer is the most frequent women's around world. Fast and precise diagnosis personalized treatment procedures are crucial in face of growing number patients. One informative at same time non-evasive diagnostic techniques based on Magnetic Resonance Imaging (MRI). This examination performed basically prone position due better visualisation tissues as well proper magnetic coil force this position. On other hand supplementary imaging (e.g. Computer...
Abstract Background 124 I Iodine (T $$_{1/2}$$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mrow/> <mml:mrow> <mml:mn>1</mml:mn> <mml:mo>/</mml:mo> <mml:mn>2</mml:mn> </mml:mrow> </mml:msub> </mml:math> = 4.18 d) is the only long-life positron emitter radioisotope of iodine that may be used for both imaging and therapy as well 131 dosimetry. Its physical characteristics permits taking advantages higher Positron Emission Tomography (PET) image quality, whereas...
Non-small cell lung cancer (NSCLC) is the most common type of cancer, and median overall survival (OS) approximately 2-3 years among patients with stage III disease. Furthermore, it one deadliest types globally due to non-specific symptoms lack a biomarker for early detection. The important decision that clinicians need make after diagnosis selection treatment schedule. This based on, others factors, risk developing metastasis.A cohort 115 NSCLC treated using chemotherapy radiotherapy (RT)...
Abstract Blood flow is most often modeled in vessels whose shape does not change over time. This approach significantly simplifies the calculations and reduces their Temporal vascular deformations affect blood patterns, deposition of atherosclerotic plaques, formation aneurysms, many other phenomena. There are two methods to consider vessel deformations: registration geometry by diagnostic imaging such as CT, MRI, ultrasound or use fluid-structure interaction (FSI) models. The first method...
We propose to endow evolutionary gamemodels with changes of the phenotypes adjustment during transient generations performed by parameters in payoff matrix which determine fitness resulting from different interactions between players. These represent an alteration access external resources which, turn, may reflect anticancer treatment. In case spatial games, these functions are represented additional lattice where another and parallel game based on cellular automata is performed. The main...
Breast cancer is one of the most common cancers in women. Typically, course disease asymptomatic early stages breast cancer. Imaging examinations allow detection cancer, which associated with increased chances a complete cure. There are many imaging techniques such as: mammography (MM), ultrasound (US), positron-emission tomography (PET), computed (CT), and magnetic resonance (MRI). These differ terms effectiveness, price, type physical phenomenon, impact on patient its availability. In this...