A5054382034- Radiation Detection and Scintillator Technologies
- Radiation Therapy and Dosimetry
- Medical Imaging Techniques and Applications
- Advanced Radiotherapy Techniques
- Nuclear Physics and Applications
- Radiation Effects in Electronics
- Cancer, Hypoxia, and Metabolism
ETH Zurich
2022-2024
Paul Scherrer Institute
2022-2024
The Jagiellonian PET (J-PET) technology, based on plastic scintillators, has been proposed as a cost effective tool for detecting range deviations during proton therapy. This study investigates the feasibility of using J-PET monitoring by means detailed Monte Carlo simulation 95 patients who underwent therapy at Cyclotron Centre Bronowice (CCB) in Krakow, Poland. 
Approach: Discrepancies between prescribed and delivered treatments were artificially introduced simulations shifts patient...
This paper reports on the implementation and shows examples of use ProTheRaMon framework for simulating delivery proton therapy treatment plans range monitoring using positron emission tomography (PET). offers complete processing plans, patient CT geometries, intra-treatment PET imaging, taking into account imaging coordinate systems activity decay during protocol specific to a given facility. We present illustrate its potential case data steps treated at Cyclotron Centre Bronowice (CCB)...
Objective.Verification of delivered proton therapy treatments is essential for reaping the many benefits modality, with most widely proposedin vivoverification technique being imaging positron emitting isotopes generated in patient during treatment using emission tomography (PET). The purpose this work to reduce computational resources and time required simulation activation GPU accelerated Monte Carlo code FRED, validate predicted activity against used GATE.Approach.We implement a...
Objective: The aim of this work is to investigate the feasibility Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. Approach: Monte Carlo simulation studies with GATE and PET image reconstruction CASToR were performed in order compare six J-PET geometries (three dual-heads three cylindrical). We simulated irradiation a PMMA phantom Single Pencil Beam (SPB) Spread-Out Bragg Peak (SOBP) various ranges. sensitivity precision each...
The PETITION (PET for InTensive care units and Innovative protON therapy) collaboration has developed two Positron Emission Tomography (PET) systems to enable novel clinical applications this imaging modality. Both PET scanners are brain featuring a bore diameter of 300 mm an axial field view length 179 mm. One the system is mobile beside scanner that can be employed in intensive unit (ICU) image vulnerable patients, who cannot moved into regular scanners. second designed proton beam therapy...
The PETITION (PET for InTensive Care units and Innovative protON therapy) project has successfully developed two new bedside Positron Emission Tomography (PET) scanners Intensive Units (ICU) proton beam therapy (PBT) applications. While the ICU device is a conventional full ring PET scanner, PBT system U-shape design ensuring suitable opening irradiation.The iterative ordered subset expectation maximisation, including image corrections, well-known algorithm reconstruction. External...
The PETITION (PET for InTensive Care units and Innovative protON therapy) project aims to design two new bed-side Positron Emission Tomography (PET) scanners Intensive Units (ICU) proton beam therapy applications. first device is intended scan deeply sedated, critically-ill patients with sepsis infection directly at the ICU, as their condition does no allow a transportation regular PET/CT facilities. second designed online image acquisition in vivo dosimetry hypoxia tracking studies.While...