K. Kacprzak
A5083379775- Radiation Detection and Scintillator Technologies
- Medical Imaging Techniques and Applications
- Atomic and Subatomic Physics Research
- Radiation Therapy and Dosimetry
- Particle physics theoretical and experimental studies
- Muon and positron interactions and applications
- Nuclear Physics and Applications
- Particle Detector Development and Performance
- Advanced MRI Techniques and Applications
- Quantum Chromodynamics and Particle Interactions
- Dark Matter and Cosmic Phenomena
- High-Energy Particle Collisions Research
- Advanced X-ray and CT Imaging
- Neutrino Physics Research
- Noncommutative and Quantum Gravity Theories
- Advanced Radiotherapy Techniques
- Diamond and Carbon-based Materials Research
- Radiopharmaceutical Chemistry and Applications
- Boron Compounds in Chemistry
- Cosmology and Gravitation Theories
- Inorganic and Organometallic Chemistry
- Black Holes and Theoretical Physics
- Ion-surface interactions and analysis
- Radiomics and Machine Learning in Medical Imaging
- Management and Organizational Practices
Jagiellonian University
2014-2025
Institute of Physics
2020-2024
Theranostics (New Zealand)
2024
University of Bari Aldo Moro
2013-2014
A detection system of the conventional PET tomograph is set-up to record data from e+ e- annihilation into two photons with energy 511 keV, and it gives information on density distribution a radiopharmaceutical in body object. In this paper we explore possibility performing three gamma imaging based ortho-positronium annihilation, as well positronium mean lifetime J-PET constructed plastic scintillators. For purposes simulations formation its were performed taking account distributions...
Positronium created in a human body during PET scans hallmarks neoplastic tissues.
We have searched for a light vector boson U, the possible carrier of "dark force", with KLOE detector at DAΦNE e+e− collider, motivated by astrophysical evidence presence dark matter in Universe. Using collisions collected an integrated luminosity 239.3 pb−1, we look dimuon mass peak reaction e+e−→μ+μ−γ, corresponding to decay U→μ+μ−. find no U signal. set 90% CL upper limit mixing parameter squared between photon and 1.6×10−5 8.6×10−7 region 520<mU<980 MeV.
Charged lepton system symmetry under combined charge, parity, and time-reversal transformation (CPT) remains scarcely tested. Despite stringent quantum-electrodynamic limits, discrepancies in predictions for the electron-positron bound state (positronium atom) motivate further investigation, including fundamental tests. While CPT noninvariance effects could be manifested non-vanishing angular correlations between final-state photons spin of annihilating positronium, measurements were...
The purpose of the presented research is estimation performance characteristics economic Total-Body Jagiellonian-PET system (TB-J-PET) constructed from plastic scintillators. are estimated according to NEMA NU-2-2018 standards utilizing GATE package. simulated detector consists 24 modules, each built out 32 scintillator strips (each with cross section 6 mm times 30 and length 140 cm or 200 cm) arranged in two layers regular 24-sided polygon circumscribing a circle diameter 78.6 cm. For...
Positronium is abundantly produced within the molecular voids of a patient’s body during positron emission tomography (PET). Its properties dynamically respond to submolecular architecture tissue and partial pressure oxygen. Current PET systems record only two annihilation photons cannot provide information about positronium lifetime. This study presents in vivo images lifetime human, for patient with glioblastoma brain tumor, by using dedicated Jagiellonian system enabling simultaneous...
Discrete symmetries play an important role in particle physics with violation of CP connected to the matter-antimatter imbalance Universe. We report most precise test P, T and invariance decays ortho-positronium, performed methodology involving polarization photons from these decays. Positronium, simplest bound state electron positron, is recent interest discrepancies reported between measured hyperfine energy structure theory at level $10^{-4}$ signaling a need for better understanding...
Neutral kaon pairs produced in phi decays anti-symmetric entangled state can be exploited to search for violation of CPT symmetry and Lorentz invariance. We present an analysis the CP-violating process phi->K_S K_L->pi+pi-pi+pi- based on 1.7 fb-1 data collected by KLOE experiment at Frascati phi-factory DAFNE. The are used perform a measurement CPT-violating parameters Delta_amu neutral kaons contest Standard Model Extension framework. measured reference frame fixed stars are: Delta_ao =...
A novel approach to tomographic data processing has been developed and evaluated using the Jagiellonian PET (J-PET) scanner as an example. We propose a system in which there is no need for powerful, local facility, capable reconstruct images on fly. Instead we introduce Field Programmable Gate Array (FPGA) System-on-Chip (SoC) platform connected directly streams coming from scanner, can perform event building, filtering, coincidence search Region-Of-Response (ROR) reconstruction by...
In living organisms, the positron-electron annihilation (occurring during PET imaging) proceeds in about 30% via creation of a metastable ortho-positronium atom. tissue, due to pick-off and conversion processes, over 98% ortho-positronia annihilate into two 511 keV photons. this article, we assess feasibility for reconstruction mean lifetime image based on annihilations The main objectives work include (i) estimation sensitivity total-body scanners imaging using 2γ (ii) spatial time...
J-PET is a detector optimized for registration of photons from the electron-positron annihilation via plastic scintillators where interact predominantly Compton scattering. Registration both primary and scattered enables to determinate linear polarization photon on event by basis with certain probability. Here we present quantitative results feasibility such measurements decay positronium explore physical limitations resolution determination 511 keV For scattering angles about 82 ∘ (where...
Abstract Background Total‐body (TB) Positron Emission Tomography (PET) is one of the most promising medical diagnostics modalities, opening new perspectives for personalized medicine, low‐dose imaging, multi‐organ dynamic imaging or kinetic modeling. The high sensitivity provided by total‐body technology can be advantageous novel tomography methods like positronium demanding registration triple coincidences. Currently, state‐of‐the‐art PET scanners use inorganic scintillators. However,...
Abstract Purpose The time-over-threshold (TOT) technique is being used widely due to itsimplications in developing the multi-channel readouts, mainly when fast signal processing required. Using TOT technique, as a measure of energy loss instead charge integration methods, significantly reduces readout costs by combining time and information. Therefore, this approach can potentially be utilized J-PET tomograph which built from plastic scintillators characterized light signals. drawback...
We have carried out a new direct search for the CP violating decay KS -> 3pi0 with 1.7 fb^-1 of e+e- collisions collected by KLOE detector at phi-factory DAFNE. searched this in sample about 5.9 x 10^8 KL events tagging means interaction calorimeter and requiring six prompt photons. With respect to our previous search, analysis has been improved increasing factor four tagged more effective background rejection fake tags spurious clusters. find no candidates data simulated samples, while...
J-PET Framework is an open-source software platform for data analysis, written in C++ and based on the ROOT package. It provides a common environment implementation of reconstruction, calibration filtering procedures, as well user-level analyses Positron Emission Tomography data. The library contains set building blocks that can be combined by users with even little programming experience, into chains processing tasks through convenient, simple well-documented API. generic input-output...
The Jagiellonian PET (J-PET) technology, based on plastic scintillators, has been proposed as a cost effective tool for detecting range deviations during proton therapy. This study investigates the feasibility of using J-PET monitoring by means detailed Monte Carlo simulation 95 patients who underwent therapy at Cyclotron Centre Bronowice (CCB) in Krakow, Poland. 
Approach: Discrepancies between prescribed and delivered treatments were artificially introduced simulations shifts patient...
This paper reports on the implementation and shows examples of use ProTheRaMon framework for simulating delivery proton therapy treatment plans range monitoring using positron emission tomography (PET). offers complete processing plans, patient CT geometries, intra-treatment PET imaging, taking into account imaging coordinate systems activity decay during protocol specific to a given facility. We present illustrate its potential case data steps treated at Cyclotron Centre Bronowice (CCB)...
The Jagiellonian Positron Emission Tomograph is the 3-layer prototype of first scanner based on plastic scintillators, consisting 192 half-metre-long strips with readouts at both ends. Compared to crystal-based detectors, scintillators are several times cheaper and could be considered as a more economical alternative crystal in future PETs. JPET also multi-photon PET prototype. For development detection, photon characterized by continuous energy spectrum, it important estimate efficiency...
The Jagiellonian Positron Emission Tomograph (J-PET) is the first PET device built from plastic scintillators. It a multi-purpose detector designed for medical imaging and studies of properties positronium atoms in porous matter living organisms. In this article we report on commissioning J-PET view decays. We present results analysis positron lifetime measured polymer. obtained prove that capable performing simultaneous density distribution annihilation points as well spectroscopy.
We perform a parametric study of the newly developed time-of-flight (TOF) image reconstruction algorithm, proposed for real-time imaging in total-body Jagiellonian PET (J-PET) scanners. The asymmetric 3D filtering kernel is applied at each most likely position electron-positron annihilation, estimated from emissions back-to-back $\gamma$-photons. optimisation its parameters studied using Monte Carlo simulations 1-mm spherical source, NEMA IEC and XCAT phantoms inside ideal J-PET scanner....
A novel plastic scintillator is developed for the application in digital positron emission tomography (PET). The novelty of concept lies 2-(4-styrylphenyl)benzoxazole as a wavelength shifter. substance has not been used dopant before. shifts scintillation spectrum towards longer wavelengths making it more suitable applications scintillators long strips geometry and light detection with silicon photomultipliers. These features open perspectives construction cost-effective MRI-compatible PET...