A5039248158- Substance Abuse Treatment and Outcomes
- Gambling Behavior and Treatments
- Alcohol Consumption and Health Effects
- Personality Disorders and Psychopathology
- Child and Adolescent Psychosocial and Emotional Development
- Behavioral Health and Interventions
- Homelessness and Social Issues
- Psychotherapy Techniques and Applications
- Digital Mental Health Interventions
- Smoking Behavior and Cessation
- Health Policy Implementation Science
- Prenatal Substance Exposure Effects
- Schizophrenia research and treatment
- Mental Health Research Topics
- Workplace Health and Well-being
- Social and Educational Sciences
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Personality Traits and Psychology
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Motivation and Self-Concept in Sports
- Neurotransmitter Receptor Influence on Behavior
- Attention Deficit Hyperactivity Disorder
- Autism Spectrum Disorder Research
- Employment and Welfare Studies
- Psychiatric care and mental health services
Karolinska Institutet
2016-2025
Stockholm University
2016-2025
University of Inland Norway
2022-2025
Stockholm Health Care Services
2014
Stockholm County Council
2006-2013
Danderyds sjukhus
2012
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2012
Regional Health
2012
Italian institute for Genomic Medicine
2012
Danish Cancer Society
2012
Type 2 diabetes mellitus (T2DM) is one of the most common chronic diseases worldwide. In high-income countries, low socioeconomic status seems to be related a high incidence T2DM, but very little known about intermediate factors this relationship. Method We performed case-cohort study in eight Western European countries nested EPIC (n = 340, 234, 3.99 million person-years follow-up). A random sub-cohort 16,835 individuals and total 12,403 incident cases T2DM were identified. Crude...
Abstract Several countries, including Canada and Australia, have developed public health-based lower-risk gambling limits to differentiate from higher-risk gambling. This study aimed identify a preliminary set of (gambling frequency, duration, expenditure, expenditure as proportion personal net income, diversity), investigate if types are linked additional harms, in Swedish context. The involved secondary analyses two online survey studies using the Gambling Disorder Identification Test...
Abstract Background and Aims Studies using smartphone apps in treatment for alcohol dependence are lacking. This study aimed to test the consumption‐reducing effects of two app‐based interventions as complement usual (TAU). Design Three‐armed, parallel, randomised controlled trial. Setting Specialised outpatient clinic within Stockholm Centre Dependency Disorders, Stockholm, Sweden. Participants 162 alcohol‐dependent adults (46% female), with no social problems or mental disorders, who had...
ABSTRACT Aims According to the prevention paradox, a majority of alcohol‐related problems in population can be attributed low moderate drinkers simply because they are more numerous than heavy drinkers, who have higher individual risk adverse outcomes. We examined paradox annual alcohol consumption, episodic drinking (HED) and among adolescents 23 European countries. Design setting Survey data from 2007 School Project on Alcohol Drugs (ESPAD) 16‐year‐old students were analysed. Participants...
<b><i>Aims:</i></b> There is a scarcity of clinical trials on psychological treatments for concurrent borderline personality disorder (BPD) and substance use (SUD). Mentalization-based treatment (MBT) have shown efficacy in several BPD. The aim the present study was to examine feasibility effectiveness MBT BPD SUD. <b><i>Methods:</i></b> Patients (<i>n</i> = 46) with SUD were randomized either combination 24) or alone 22). Outcome...
<b><i>Background/Aims:</i></b> Most problematic alcohol users never seek professional help to reduce their use, and Web-based interventions might fulfill users' unmet needs for support. <b><i>Methods:</i></b> This randomized controlled trial compared two open interventions, one extended self-help program brief screening feedback intervention, with an assessment-only control group. Participants were 633 Internet seekers at least hazardous use...
While dopaminergic mechanisms in amphetamine-taking behavior have been extensively studied, the contribution of endogenous opioid system is less clear. We assessed effects an antagonist, naltrexone (50 mg), on subjective response to oral dose dexamphetamine (30 mg) 12 healthy volunteers a double-blind, placebo-controlled design. Volunteers received total 4 combinations study preparation (placebo-naltrexone, placebo-amphetamine) over occasions with 1-week intervals. The primary objective was...
Abstract Objective Alcohol and Other Drug (AOD) disorders cause substantial harm. Effective Substance Use Treatment (SUT) exists, but long-term outcomes remain inconclusive. This study used a 20-year prospective follow-up of 1248 service users entering SUT in Stockholm, Sweden, 2000–2002 to elaborate on how different dimensions may be measured by register-based indicators. Baseline characteristics attrition bias were explicated, examined. Results Register-based indicators are valuable, they...
The association between problem gambling and suicidal behaviours is well established in treatment seeking populations, but less explored among sub-clinical gamblers the general population. aim of this study was to examine (including moderate risk gambling) ideations/suicide attempts, Swedish Another compare with without suicide ideation/attempts. A case-control nested Swelogs cohort used. Both ideations attempts were about twice as frequent cases compared controls. After controlling for...
Abstract Objectives The Gambling Disorder Identification Test (GDIT) is a recently developed self‐report measure. GDIT includes items with multiple response options that are either based on frequency or time, and item theory evaluations of these could yield vital knowledge its measurement performance. Methods was evaluated using Rasch analysis in study involving 597 Swedish gamblers. Results In three‐dimensional model, the difficulty range extended from −1.88 to 4.06 increased higher time‐...
The aims of this naturalistic study are to present patient characteristics and analyse various outcome measures at termination for psychoanalytic psychotherapies with young adults. Patients ( n =134) between 18 25 years were included, whom 92 received individual 42 group therapy. One third had a self‐reported personality disorder. patients considerably more troubled than Swedish norm groups intake they showed improvement on all during However, the post therapy means did not fully reach...
This study aimed to describe changes in Swedish alcohol habits during a period of “harmonization” with European Union policy. Three random samples collected the years 1997 (n=997), 2001 (n=893) and 2005 (n=914) were compared. Alcohol hazardous consumption was measured AUDIT (Alcohol Use Disorders Identification Test) distributed respondents by post. Results somewhat diverse, but significant occurred among two subgroups population: for women age group between 28 60 years, scores peaked 2001....
This study aimed to survey the changes in alcohol habits during a period with European Union legal practices.Alcohol Sweden were surveyed general Swedish population at four timepoints, 1997, 2001, 2005 and 2009, using 10-item AUDIT questionnaire.Four separate randomly drawn cross-sectional samples of 1,250 individuals each timepoint.An average 70% sampled responded questionnaire. Men had higher total scores than women but increased among 61-71 years old decreased men old. Younger 17-27 their...
Aims: The Alcohol Use Disorders Identification Test (AUDIT) is a well-established and widely used screening instrument. It has been shown that AUDIT good criterion validity in relation to alcohol abuse dependence according DSM-IV, but it not yet validated following the introduction of DSM-5 diagnostic system. aim this study was evaluate concurrent for self-reported severity levels Disorder (AUD) Swedish general population sample. Methods: A postal questionnaire, containing 13-item brief AUD...
This study described the psychometric properties of Swedish version Outcome Questionnaire (OQ-45.2) in a substance abuse sample (N=227). The test were satisfactory except for somewhat low internal consistency social role subscale. results similar to those obtained other countries but systematic international comparisons are still lacking.
The present study aimed to examine whether patients' pretherapy motivation was related other patient characteristics and it predicted retention in psychotherapy. Data were collected within a naturalistic outcome of various forms psychotherapy for patients (N = 172) with substance use disorders (SUD). Therapy measured using the Client Motivation Scale (CMOTS), including variables autonomous motivation, controlled amotivation. Female had higher levels (d .53), lower -.32), amotivation -.62)....
The comparative psychometric properties of self-report measures for gambling are insufficiently evaluated, in particular regarding factor structure and item response properties. Confirmatory Rasch analyses were tested three widely used assessing problem related constructs, that is, the Problem Gambling Severity Index (PGSI), Pathological Measure (PPGM), NORC Diagnostic Screen Problems (NODS). Psychometric data was analyzed, including help-seeking recreational samples (N = 598). Compared to...
The aim of the study was to assess feasibility naltrexone as a potential pharmacotherapy for amphetamine dependence. design an open-label clinical trial with 20 amphetamine-dependent patients receiving 12 weeks treatment comprised (50 mg) along relapse prevention therapy. Patients were assessed weekly adverse events and compliance medication. Tolerability measured by patient's self-report observed effects plasma markers hepatotoxicity. Compliance number days attended presence naltrexone's...
Objectives. This study examines how young adult patients' ideas of cure prior to psychoanalytic psychotherapy are associated with premature termination, early alliance and therapy outcome. The hypotheses were that about approaching one's problems would be related fewer terminations, higher better outcome, than distancing oneself from problems. Design. Young patients ( N =46) interviewed regarding their cure. Outcome measures administered pre‐ post‐therapy. Alliance in treatment. Methods. A...