Nannan Yang

ORCID: 0000-0002-0032-6348
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Research Areas
  • Electric and Hybrid Vehicle Technologies
  • Advanced Battery Technologies Research
  • Antimicrobial Peptides and Activities
  • Electric Vehicles and Infrastructure
  • Plant Disease Resistance and Genetics
  • RNA Interference and Gene Delivery
  • Enzyme Structure and Function
  • Plant Molecular Biology Research
  • Semiconductor Quantum Structures and Devices
  • Mycotoxins in Agriculture and Food
  • Magnetic Properties of Alloys
  • Infant Nutrition and Health
  • Genomic variations and chromosomal abnormalities
  • Prenatal Screening and Diagnostics
  • Wheat and Barley Genetics and Pathology
  • CRISPR and Genetic Engineering
  • Advanced Algorithms and Applications
  • Electronic Packaging and Soldering Technologies
  • Intermetallics and Advanced Alloy Properties
  • Plant tissue culture and regeneration
  • Vehicle emissions and performance
  • 3D IC and TSV technologies
  • Magnetic and transport properties of perovskites and related materials
  • Advanced Semiconductor Detectors and Materials
  • Genetic Mapping and Diversity in Plants and Animals

Hubei University of Medicine
2024

Jilin Normal University
2010-2024

Wagga Wagga Base Hospital
2022-2023

Hangzhou Women’s Hospital
2023

Shanghai Electric (China)
2022

UiT The Arctic University of Norway
2002-2021

Jilin Engineering Normal University
2021

Ruijin Hospital
2021

Shanghai Jiao Tong University
2021

State Key Laboratory of Automotive Simulation and Control
2015-2020

Summary Natural antisense transcripts ( NAT s) are commonly observed in eukaryotic genomes, but only a limited number of such genes have been identified as being involved gene regulation plants. In this research, we investigated the function small RNA derived from fiber cell development. Using map‐based cloning strategy for first time tetraploid cotton, cloned naked seed mutant N 1 ) encoding MYBMIXTA ‐like transcription factor 3 MML )/ Gh MYB 25‐like chromosome A12, 3_A12 , that is...

10.1111/nph.13860 article EN New Phytologist 2016-02-02

Tunable surface plasmon resonance (SPR) of silver (Ag) films fabricated via magnetron sputtering technology was achieved. The experimental findings demonstrated that the thickness Ag film gradually increased with increasing time, resulting in a red shift SPR peak. To investigate charge transfer (CT) induced by metal/probe molecule/organic semiconductor system, composite system composed nanoparticles, mercaptobenzoic acid (MBA), and polyaniline (PANI) prepared layered assembly method....

10.1021/acs.jpcc.4c00292 article EN The Journal of Physical Chemistry C 2024-02-22

The relatively low efficiency of biolistic transformation and subsequent integration multiple copies the introduced gene/s significantly complicate genetic modification wheat (Triticum aestivum) other plant species. One key factors contributing to reproducibility this method is uniformity DNA/gold suspension, which dependent on coating procedure employed. It was also shown recently that relative frequency single copy transgene inserts could be increased through use nanogram quantities DNA...

10.1186/s12870-018-1326-1 article EN cc-by BMC Plant Biology 2018-06-25

// Liv-Marie Eike 1 , Nannan Yang 2 Øystein Rekdal 1, 3 Baldur Sveinbjørnsson Department of Molecular Inflammation Research, Medical Biology, Faculty Health Sciences, University Tromsø, Norway Community Medicine, Lytix Biopharma, Oslo, Correspondence to: Sveinbjørnsson, e-mail: baldur.sveinbjornsson@uit.no Keywords: oncolytic peptide, DAMPs, melanoma Received: March 25, 2015 Accepted: October 01, Published: 13, ABSTRACT Host defense peptides (HDPs) are naturally occurring molecules found in...

10.18632/oncotarget.5308 article EN Oncotarget 2015-10-13

Recent studies have demonstrated that radiotherapy is able to induce anti-tumor immune responses in addition mediating direct cytotoxic effects. Cancer-associated fibroblasts (CAFs) are central constituents of the tumor stroma and participate actively immunoregulation. However, capacity CAFs influence context still poorly understood. This study was undertaken determine whether ionizing radiation alters CAF-mediated immunoregulatory effects on natural killer (NK) cells. were isolated from...

10.3389/fimmu.2020.602530 article EN cc-by Frontiers in Immunology 2021-01-22

An electron transport layer (ETL) with excellent conductivity and suitable band alignment plays a key role in accelerating charge extraction transfer for achieving highly efficient planar perovskite solar cells (PSCs). Herein, novel diluted-cadmium sulfide quantum dot (CdS QD)-assisted SnO2 ETL has been developed low-temperature fabrication process. The slight addition of CdS QDs first enhances the crystallinity flatness ETLs so that it provides promising workstation to obtain high-quality...

10.1021/acsami.1c00896 article EN ACS Applied Materials & Interfaces 2021-03-31

The cytotoxic activity of 10 analogs the idealized amphipathic helical 21-mer peptide (KAAKKAA)3, where three Ala residues at different positions have been replaced with Trp residues, has investigated. peptide's was found to be markedly dependent upon position within hydrophobic sector an α-helix. peptides located opposite cationic displayed no antitumor activity, whereas those two or adjacent exhibited high when tested against cancer cell lines. Dye release experiments revealed that in...

10.1074/jbc.m111.279281 article EN cc-by Journal of Biological Chemistry 2011-11-05

Strong and tough synthetic hydrogels have received ever-increasing interests due to their potential applications as load-bearing structural materials. However, strong, tough, recyclable in different forms that can be generated by methods according various practical still remain an intrinsic bottleneck. A simple one-pot synthesis of multiurea linkage segmented linear copolymers with easy recyclability, hybridization, processability, including compression molding, solution casting, spinning...

10.1002/marc.201700275 article EN Macromolecular Rapid Communications 2017-07-10

Abstract A number of shortened derivatives the lactoferrin model peptide L12, PAWRKAFRWAKRMLKKAA, were designed in order to elucidate structural basis for antitumour activity derivatives. Three tumour cell lines included study and toxicity determined by measuring lysis human red blood cells fibroblasts. The results demonstrated a strong correlation between net positive charge, which charge close +7 was essential high activity. In increase shortest with less than +7, hydrophobicity had be...

10.1002/psc.470 article EN Journal of Peptide Science 2003-11-10

Summary Plants respond to abiotic stresses by changes in gene regulation, including stress‐inducible expression of transcriptional activators and repressors. One the best characterized families drought‐related transcription factors are dehydration‐responsive element binding ( DREB ) proteins, known as C‐repeat CBF ). The wheat / Ta RAP 2.1L was isolated from drought‐affected tissues using a DRE bait yeast one‐hybrid screen. is induced elevated abscisic acid, drought cold. A C‐terminal...

10.1111/pbi.12432 article EN other-oa Plant Biotechnology Journal 2015-07-06

Summary Homeodomain leucine zipper class I ( HD ‐Zip I) transcription factors TF s) play key roles in the regulation of plant growth and development under stresses. Functions Ta HDZ ipI‐2 gene isolated from endosperm developing wheat grain were revealed. Molecular characterization protein included studies its dimerisation, protein– DNA interactions activation properties using pull‐down assays, in‐yeast methods transient expression assays cells. The analysis functions was performed transgenic...

10.1111/nph.13919 article EN publisher-specific-oa New Phytologist 2016-03-15

Abstract: A number of peptide analogs derived from the N‐terminal α‐helical region bovine lactoferrin (LFB 14–31), were designed in order to investigate how deviating numbers and positions positively charged residues aromatic affected their activity against prokaryotic, normal transformed eukaryotic cells. Most LFB derivatives highly active both Escherichia coli Staphylococcus aureus. The peptides more tumor cell lines MethA, HT‐29 MT‐1 than cells . that most had all cationic concentrated...

10.1034/j.1399-3011.2002.21008.x article EN Journal of Peptide Research 2002-10-01

Expression of the wheat dehydrin gene Cor410b is induced several fold above its non-stressed levels upon exposure to stresses such as cold, drought and wounding. Deletion analysis TdCor410b promoter revealed a single functional C-repeat (CRT) element. Seven transcription factors (TFs) were shown bind this CRT element using yeast one-hybrid screens barley cDNA libraries, which only one belonged DREB class TFs. The remaining six encoded ethylene response (ERFs) belong three separate...

10.1371/journal.pone.0058713 article EN cc-by PLoS ONE 2013-03-19

Septoria tritici blotch (STB) has been ranked the third most important wheat disease in world, threatening a large area of production. Although major genes play an role protection against Zymoseptoria infection, lifespan their resistance unfortunately is very short modern production systems. Combinations quantitative with minor effects, therefore, are believed to have prolonged and more durable Z. tritici. In this study, new trait loci (QTLs) were identified that responsible for...

10.3389/fpls.2022.990915 article EN cc-by Frontiers in Plant Science 2022-10-24

Abstract A peptide L5 (PAWRKAFRWAWRMLKKAA), derived from the N ‐terminal α‐helical region of bovine lactoferrin (LFB 14–31), that is highly active against several tumour cell lines was reported earlier. In this study, a number analogues were designed in order to investigate how subsequent replacements aromatic amino acids with three representing different structural parameters influenced antitumour activity and specificity relative normal human cells. The Trp residues substituted by Lys, Ile...

10.1002/psc.457 article EN Journal of Peptide Science 2003-04-23

Given its highly coupled multi-power sources with diverse dynamic response characteristics, the mode transition process of a power-split Hybrid Electric Vehicle (HEV) can easily lead to unanticipated passenger-felt jerks. Moreover, difficulties in parameter estimation, especially power-source torque result new challenges for jerk reduction. These two aspects entangle each other and constitute complicated coupling problem which obstructs realization valid anti-jerk method. In this study,...

10.3390/en11061537 article EN cc-by Energies 2018-06-13

Mesoporous silica nanoparticles (MSNs) are ideal nanocarriers that have recently gained attention in important bioapplications such as drug, gene, and protein delivery. The efficacy of endocytosis greatly affects the biological functions MSNs. In present study, we investigated effect cationic liposomes Lipofectamine 2000 on cellular uptake MSNs cytotoxicity combining with both vitro vivo. Therefore, mesoporous an average diameter 130 nm negative surface charge were synthesized characterized....

10.1166/jbn.2013.1691 article EN Journal of Biomedical Nanotechnology 2013-08-07

LaFe11.65Si1.35/Cu core-shell powders were achieved by self-designed magnetron sputtering system, which presents a better solidification during spark plasma sintering in comparison to the naked LaFe11.65Si1.35 powders. Much higher compressive strength, lower corrosion current density and magnetic hysteresis losses are for sintered sample of without significant decrease entropy change. The maximum 105.6 MPa/16.8 MPa, 1.08 × 10−3A/cm2/3.03 10−3 A/cm2 1.33 J/kg/2.71 J/kg, respectively samples...

10.1063/1.4952757 article EN cc-by AIP Advances 2016-05-01
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