- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Infective Endocarditis Diagnosis and Management
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Aortic Disease and Treatment Approaches
- Sleep and Wakefulness Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Retinal Imaging and Analysis
- Central Venous Catheters and Hemodialysis
- Mechanical Circulatory Support Devices
- Peripheral Artery Disease Management
- Optical Coherence Tomography Applications
- Restless Legs Syndrome Research
- Venous Thromboembolism Diagnosis and Management
- Sleep and related disorders
- Heart Failure Treatment and Management
- Vascular Procedures and Complications
- Pulmonary Hypertension Research and Treatments
- Advanced MRI Techniques and Applications
- Acute Ischemic Stroke Management
Oxford University Hospitals NHS Trust
2024
University of Padua
2021-2023
Background The impact of transcatheter aortic valve replacement (TAVR) leaflet design on long-term device performance is still unknown. This study sought to compare the clinical and hemodynamic outcomes intra- (IA) versus supra-annular (SA) TAVR designs up-to 10-years following implantation. Methods Consecutive patients with at least 5-years follow-up for severe symptomatic stenosis from June 2007 December 2016 were included. Bioprosthetic failure (BVF) deterioration (HVD) defined according...
Primary percutaneous coronary intervention (pPCI) has revolutionized the prognosis of ST-segment elevation myocardial infarction (STEMI) and is gold standard treatment. As a result its success, number pPCI centres expanded worldwide. Despite decades advancements, clinical outcomes in STEMI patients have plateaued. Out-of-hospital cardiac arrest cardiogenic shock remain major cause high in-hospital mortality, whilst growing burden heart failure long-term survivors presents problem. Many...
Objective The European Society of Cardiology guidelines have recently defined new cut-offs for pulmonary hypertension (PH) and vasculature resistance (PVR; median artery pressure (mPAP) >20 instead 25 mm Hg PVR >2 3 Wood unit). prognostic value this updated classification after transcatheter aortic valve implantation (TAVI) is unknown. Methods 579 consecutive patients treated by TAVI with preprocedural right heart catheterisation evaluation were included. Patients grouped as: (1) no...
Summary Alteration of the circadian sleep−wake rhythm has been suggested in patients affected by idiopathic rapid eye movement sleep behaviour disorder. Because actigraphy is validated instrument to monitor cycle, aim present study was investigate with disorder compared healthy aged controls. Fourteen‐day actigraphic recording, a comprehensive interview, and cognitive behavioural domains were investigated disorder, controls similar for age, sex performances. Patients showed reduced relative...
Among vascular closure devices (VCDs), the novel collagen plug-based MANTA VCD is first designed for large bore percutaneous access. We aimed to assess features and predictors of access-site complications in an unselected trans-femoral transcatheter aortic valve replacement (TF-TAVR) population.Patients undergoing arteriotomy with 18F following TF-TAVR at a tertiary care center from September 2019 January 2021 were prospectively analyzed. Primary Outcome was access-site-related according...
Primary percutaneous coronary intervention (pPCI) has revolutionized the prognosis of ST-segment ele-vation myocardial infarction (STEMI) and is gold standard treatment. As a result its success, number pPCI centres expanded worldwide. Despite decades advancements, clinical outcomes in STEMI patients have plateaued. Out-of-hospital car-diac arrest cardiogenic shock remain major cause high in-hospital mortality, whilst growing burden heart failure long-term survivors presents problem. Many...
To assess the impact of conventional transcatheter heart valve (THV) commissural alignment techniques on THV/coronary overlap and coronary access (CA) after aortic replacement (TAVR) in bicuspid (BAV).Specific Evolut Pro/Pro + Acurate Neo2 THV orientations are associated with reduced neo-commissural ostia tricuspid anatomy. Whether standard orientation effective also setting BAV anatomy has not been studied.The DA VINCI (Definition trAnscatheter Valve orIeNtation biCuspId valve) pilot study...
Abstract Background Whether assessment of myocardial viability (MV) by delayed enhancement cardiac magnetic resonance (DE-CMR) can help identify patient with severe ischemic left ventricular (LV) disfunction who might benefit from coronary revascularization has not been yet clearly established. Moreover, although improvement in LV function is one the heart failure treatment goal, its prognostic implication remains controversial. Methods We retrospectively evaluated all consecutive patients a...
Abstract Background Pulmonary embolism (P.E.) is defined as an acute occlusion/subocclusion of pulmonary vascular vessels with a ranging clinical manifestation. A reperfusion therapy (preferably systemic thrombolysis) represents the first line for high-risk patients. However, percutaneous treatment option should be considered when thrombolysis contraindicated or has failed. Case report 73 y.o. male, former smoker history hypertension and dyslipidemia, was admitted hemorrhagic stroke...