Spyridon Davakis

ORCID: 0000-0002-0042-436X
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About
Contact & Profiles
Research Areas
  • Esophageal Cancer Research and Treatment
  • Esophageal and GI Pathology
  • Gastric Cancer Management and Outcomes
  • Lung Cancer Diagnosis and Treatment
  • COVID-19 and healthcare impacts
  • Bariatric Surgery and Outcomes
  • Liver Disease Diagnosis and Treatment
  • Body Contouring and Surgery
  • Congenital Diaphragmatic Hernia Studies
  • Cardiac, Anesthesia and Surgical Outcomes
  • Pancreatic and Hepatic Oncology Research
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Gastrointestinal disorders and treatments
  • Congenital Anomalies and Fetal Surgery
  • Hernia repair and management
  • Tracheal and airway disorders
  • Colorectal Cancer Surgical Treatments
  • Liver physiology and pathology
  • Gastroesophageal reflux and treatments
  • Aortic aneurysm repair treatments
  • Metastasis and carcinoma case studies
  • Neuroendocrine Tumor Research Advances
  • Immune Response and Inflammation
  • Global Health Care Issues
  • Appendicitis Diagnosis and Management

Laiko General Hospital of Athens
2017-2024

National and Kapodistrian University of Athens
2016-2024

American Society for Gastrointestinal Endoscopy
2022

Interbalkan Medical Center
2021

Athens State University
2021

Mid Essex Hospital Services NHS Trust
2019-2020

Broomfield Hospital
2019-2020

Mercy University Hospital
2017

Aretaeio Hospital
2017

Cleveland Clinic
2017

Background/Aim: Fournier9s gangrene is an uncommon, but extremely serious condition of necrotizing, soft tissue infection. There a great debate regarding the management larger defects and wound closure, with various techniques being described in current literature. We aimed to present surgical extensive treated successfully Vacuum-assisted closure (VAC) therapy, novel approach treatment algorithm that can lead paradigm shift. Case: A 66-year-old male patient was debridement, protective...

10.21873/invivo.11936 article EN In Vivo 2020-01-01

This study investigated the anti-inflammatory effect of apigenin in an experimental model acute pancreatitis. Inflammatory response was reflected by tissue expression cytokine TNF-α coupled with histological examination.Wistar rats were divided into three groups: Sham-group animals underwent laparotomy only, without any other interventions. Control-group and bilio-pancreatic duct ligation to induce pancreatitis administration. Apigenin group further treated apigenin. Euthanasia performed at...

10.21873/invivo.11583 article EN In Vivo 2019-01-01

Locally advanced pancreatic cancer (LAPC) is found in about 40% of patients with cancer. Irreversible electroporation (IRE) a nonthermal ablative technique that provides an alternative LAPC and can be safely combined chemotherapy.From 2015 until October 2019, we performed laparotomic IRE total 40 stage III LAPC. The median age these was 65.2 years (range: 46 to 81 y), the tumor size 3.8 cm 2 5.2 cm). 33 were treated preoperatively FOLFIRINOX or nab-paclitaxel plus gemcitabine case disease...

10.1097/coc.0000000000000826 article EN American Journal of Clinical Oncology 2021-05-12

Background/Aim: Esophageal and gastro-esophageal junction cancer is a major cause of cancer-related mortality, with poor prognosis. Toll-like receptors (TLRs) play significant role in the innate immune system; their increased expression has been associated esophageal adenocarcinoma. This study aimed to determine association between TLR-3 TLR-4 clinical oncological outcomes patients that underwent esophagectomy for cancer. Patients Methods: retrospective analysis prospectively collected data...

10.21873/anticanres.16492 article EN Anticancer Research 2023-06-23

Idiopathic granulomatous mastitis (IGM), is a rare entity of chronic inflammatory disorder the breast unknown etiology. Very few cases have been described so far, almost exclusively in women. Here we describe case IGM 53-year-old man presented with right mass, progressively enlarging during last 6 months. Due to findings clinical examination and CT-scan, suspicion for potentially malignant lesion was given decision surgical resection made. Microscopic analysis specimen showed non-caseating...

10.21037/atm.2017.05.24 article EN Annals of Translational Medicine 2017-08-01

Summary Utilization of totally minimally invasive esophagectomy for cancer is on the rise. Esophagogastric anastomosis mechanically or robotically performed routinely; little report exists hand-sewn esophagogastric anastomosis. This largest so far study with thoracoscopic during fully two-stage esophageal in prone position. Consecutive esophagectomies were by one surgical team, from September 2016 to March 2019. All operations technically identical terms patient positioning, approach, extend...

10.1093/dote/doaa106 article EN Diseases of the Esophagus 2020-11-12

Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer and third leading cause of death worldwide. The management HCC complex, with surgical treatment providing long-term survival in eligible patients. This study aims to present experience aggressive Greece. Methods: a retrospective multicentre clinical 242 Results: Most patients were male (79%) had median age 71 yrs. According recent BCLC criteria, 172 (71.1%) classified as 0-A stage, 33 (13.6%) B, 37 (15.3%) C....

10.3390/cancers14184387 article EN Cancers 2022-09-09

Abdominal aortic aneurysm (AAA) formation is associated with by inflammation and matrix degradation. This study tested the hypothesis that calprotectin, a novel biomarker for inflammation, as well established biomarkers such C-reactive protein (CRP) metalloproteinase- 9 (MMP-9) could also be indicative inflammatory during AAA pathogenesis progression. We evaluated correlation of serum soluble Receptor Advanced Glycation End Products (sRAGE) diameter calprotectin levels.Rat abdominal aortas...

10.2174/1570161115666170202155724 article EN Current Vascular Pharmacology 2017-02-23

Introduction A colorectal inflammatory myofibroblastic tumour (IMT) is a rare but benign entity masquerading as malignant tumour. Although the lung considered most common site of occurrence, IMTs may arise in diverse extrapulmonary locations. We describe case colonic IMT patient who presented emergency setting. Case History 77-year-old man was admitted at our department with acute abdominal pain. Physical examination revealed vague tenderness lower abdomen and non-palpable masses....

10.1308/rcsann.2017.0064 article EN Annals of The Royal College of Surgeons of England 2017-05-01

The presence of vermiform appendix in an inguinal hernia sac is known as Amyand's hernia. complicated with acute appendicitis extremely rare entity challenging diagnosis and large debate about the optimal treatment option. We report a case 58-year-old man presenting to Emergency Department incarcerated right At laparoscopy, inflamed was identified within canal, representing indirect A laparoscopic appendicectomy performed followed by trans-abdominal pre-peritoneal mesh repair aforementioned...

10.1093/jscr/rjz173 article EN cc-by-nc Journal of Surgical Case Reports 2019-05-13

Esophagectomy is a major surgical procedure associated with significant risk of morbidity and mortality that has traditionally been performed by an open approach. Although minimally invasive procedures for benign esophageal disease have widely accepted worldwide, they not yet established the treatment malignancy.A total 137 consecutive hybrid esophagectomies cancer were same team. Surgical approach included either 2-stage or 3-stage minimally-invasive esophagectomy.Median age patients was 64...

10.21873/anticanres.14129 article EN Anticancer Research 2020-03-01

Laparoscopic total gastrectomy is on the rise. One of most technically demanding steps approach construction esophago-jejunal anastomosis. Several laparoscopic anastomotic techniques have been described, like linear stapler side-to-side or circular end-to-side anastomosis; limited data exist regarding hand-sewn The study took place between January 2018 and June 2021. Patients enrolled in this were adults with proximal gastric esophago-gastric junction Siewert type III tumors that underwent...

10.3390/cancers13184709 article EN Cancers 2021-09-20
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