A5015792184- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Orthopedic Surgery and Rehabilitation
- Hernia repair and management
- Shoulder Injury and Treatment
- Knee injuries and reconstruction techniques
- Liver Disease Diagnosis and Treatment
- Hip and Femur Fractures
- Pelvic and Acetabular Injuries
- Shoulder and Clavicle Injuries
- Liver Disease and Transplantation
- Elbow and Forearm Trauma Treatment
- MicroRNA in disease regulation
- Adipokines, Inflammation, and Metabolic Diseases
- Adipose Tissue and Metabolism
- Medical Malpractice and Liability Issues
- Gallbladder and Bile Duct Disorders
- Urinary and Genital Oncology Studies
- Sarcoma Diagnosis and Treatment
- Abdominal Surgery and Complications
- Bone fractures and treatments
- Clinical practice guidelines implementation
- Cardiovascular Syncope and Autonomic Disorders
- Abdominal Trauma and Injuries
Medical University of Graz
2014-2023
Graz University Hospital
2023
Orthopädische Universitätsklinik
2015
Voestalpine (Austria)
2011
Universitätszahnklinik Wien
2006
NanoTecCenter Weiz Forschungsgesellschaft (Austria)
2006
University of Göttingen
1988
Adipose tissue contains thermogenic adipocytes (i.e., brown and brite/beige) that oxidize nutrients at exceptionally high rates via nonshivering thermogenesis. Its recent discovery in adult humans has opened up new avenues to fight obesity related disorders such as diabetes. Here, we identified miR-26a -26b key regulators of human white brite adipocyte differentiation. Both microRNAs are upregulated early adipogenesis, their inhibition prevented lipid accumulation while overexpression...
A periprosthetic joint infection is one of the most challenging complications associated with THA and TKA. In diagnostic process for detecting a infection, important steps analysis laboratory biomarkers.We investigated sensitivity specificity biomarkers procalcitonin, interleukin 6 (IL-6), interferon α (IFN-α) as compared conventional (C-reactive protein [CRP], leukocyte level) revision arthroplasties.We prospectively included analyzed 84 patients (124 arthroplasties). The blood parameters...
Background: Outcome measurement following surgery is increasingly the focus of attention in current health-care debates because rising costs medical care and large variety operative options. The purpose present study was to correlate quality life after volar locked plate fixation unstable intra-articular distal radial fractures with functional radiographic results as well quality-of-life data from population norms. Methods: Fifty-four consecutive patients a mean age sixty-three years were...
The early and accurate diagnosis of periprosthetic joint infection (PJI) can be challenging. Fibrinogen plays an important role in mediating inflammation bacterial infections therefore could a valuable biomarker for PJI. purpose this study was to investigate the sensitivity specificity serum levels fibrinogen detecting PJI, compare results with established PJI biomarkers C-reactive protein (CRP) leukocyte count. Eighty-four patients (124 surgeries) were prospectively included. preoperatively...
Abstract Purpose The purpose of this study was to provide a matched cohort comparison clinical and functional outcome scores, range motion quality life following unicompartmental knee arthroplasty (UKA) or total (TKA). hypothesis that patients receiving UKA report better results than comparable who receive conventional TKA. Methods Clinical 35 with medial end-stage osteoarthritis had received fixed-bearing were compared the TKA from same manufacturer by surgeon. Outcome scores measured...
Abstract Introduction The aim of this study was to assess the prevalence protein energy malnutrition (PEM) and correlation with poor post-operative outcome in elderly undergoing primary total hip arthroplasty (THA). Hypothesis Patients PEM would have inferior after THA. Materials method We retrospectively evaluated nutritional status 220 hospitalized patients THA, 65 years older. assessed using serum albumin lymphocyte count (TLC). Studied parameters were length pre-operative stay,...
The aim of this prospective study was to assess the long-term clinical, radiological, functional, and quality life (QoL)-related outcome patients treated with synthetic Ligament Advanced Reinforcement System (LARS) device for anterior cruciate ligament (ACL) rupture.A total 41 who underwent ACL reconstruction LARS (mean age 39.8 years (SD 12.1 ); 32% females (n = 13)) were prospectively included between August 2001 March 2005. MRI scans radiographs performed at a median follow-up 2.0...
Metabolomic profiles of tissues could greatly contribute to advancements in personalized medicine but are influenced by differences adopted preanalytical procedures; nonhomogeneous pre- and post-excision ischemia times potential sources variability. In this study, we monitored the impact on metabolic profiles, acquired with high-resolution magic-angle-spinning (1)H NMR, 162 human liver samples collected during up 6 h after routine surgery. The changed significantly as a function...
Pyogenic liver abscess (PLA) remains a serious disease with mortality of 6-14%.Clinical data 76 patients PLA were analyzed. Treatment options comprised antibiotics, percutaneous puncture/drainage, endoscopic papillotomy/stenting and/or surgery as indicated.Fifty-eight (76%) had single and 18 multiple (right lobe: 65%; both lobes: 22%). The most frequent etiologies were: biliary (38%), hematogenous posttraumatic (11%). Factors associated the need for included gallbladder empyema, fistulas,...
Abstract Purpose Metaphyseal fixation in revision total knee arthroplasty (RTKA) is a very promising treatment option for extended bone defects. Currently published mid-term results remain limited. The purpose was to analyse the implant durability, clinical and radiological RTKA when using metaphyseal sleeves. Methods Clinical follow-up examinations were performed 92 patients (93 knees) with hybrid technique (cementless sleeves stem). Radiographic measurements regarding osseointegration at...
Abstract Background Intramedullary nailing of pertrochanteric femoral fractures has grown in popularity over the past 2 decades likely because this procedure is associated with a low risk for postoperative morbidity and fast recovery function. The evaluation outcomes mainly been based on objective measures. purpose present study to correlate patients’ health-related quality life results after intramedullary outcome Methods We conducted single-center including 62 patients (mean age 80 ± 10...
This study aimed to present functional results and patient's health related quality of life (HRQOL) data ten years after volar locked plate fixation (VPF) unstable intra-articular distal radial fractures (DRF).Thirty-nine patients with a mean age sixty-one were operatively treated VPF fractures. They evaluated two, six, postoperatively according the Gartland Werley score. For subjective evaluation Short Form 36 (SF-36) Disability Arm, Shoulder Hand (DASH) questionnaires adopted.Overall,...
Abstract Purpose The purpose of this study was to compare the clinical and functional outcome scores following total knee arthroplasty (TKA) with two different systems. hypothesis that there is a difference between patients receiving newer design than those predecessor. Methods Two hundred who underwent TKA were randomized into groups: received either Attune or PFC Sigma (both DePuy Synthes, Warsaw, IN). Clinically, Knee Society Function Scores (KS FS), Western Ontario McMaster Universities...
An increasing number of patients are raising their voices in online forums to exchange health-related information. Facebook is the leading social media platform with more than 1 billion international daily users recorded summer 2015. has a dynamic audience and utilized ways, discussing medical issues being one them. Ewing sarcoma mainly affects teenagers young adults. Additionally, many individuals within this age group regular Facebook. However, little known about impact modern way...
Obesity is strongly associated with mortality and morbidity, but there a lack of data on its impact health-related quality life (HRQoL) across different age groups. Therefore, this study’s objective was to determine the association between body mass index (BMI) HRQoL in Austrian adult population based groups using 36-Item Short Form (SF-36) survey. Methods: The SF-36 survey sent 500 randomly assigned adults (response rate: 80.6%). This study assessed subscale component scores gender, level...
This study investigated the association of preoperative 25-hydroxy (25 (OH)) vitamin D levels with postoperative complications in osteoporotic hip fracture patients following surgery. We hypothesized that low concentrations 25 (OH) might have an increased risk developing adverse outcomes. Between January 2019 and December 2020, a retrospective observational was conducted, including low-energy fragility fractures at proximal femur. Regarding levels, were divided into two groups (<30 ng/mL...
Summary Background Environmental stimuli and well-being are considered to be significant factors in patients’ rehabilitation. The aim of this study was describe the effect colors art hospital rooms on recovery after total hip or knee arthroplasty. Methods We performed a prospective randomized, controlled including 80 patients. intervention group randomized colored patient while control received medical care conventional rooms. Data were collected preoperatively postoperatively (3 6 days...