Inflammatory myofibroblastic tumor is a histopathologically distinctive neoplasm of children and young adults. According to World Health Organization (WHO) classification, inflammatory an intermediate-grade tumor, with potential for recurrence rare metastasis. There are no definite histopathologic, molecular, or cytogenetic features predict malignant transformation, recurrence, metastasis.A 5-year retrospective study diagnosed tumors various anatomic sites was conducted correlate anaplastic...

Introduction: Meningiomas are slow growing primary central nervous system (CNS) tumours attached to the duramater, which arise from meningothelial cells of arachnoid.Grading meningioma based on histological findings assisted with supplementary immunohistochemical studies, predicts prognosis good precision.Aim: To evaluate proliferative markers and correlate various subtypes grade. Materials Methods:A total 224 meningiomas, diagnosed between January1995 October 2011were graded according WHO...

We report a case of 21-year-old Indian man with an 8-month history left-sided headache, maxillary sinus mass, proptosis and swelling the left temple, whose contrast-enhanced CT scans paranasal sinuses showed enhancing, destructive soft tissue mass involving sinus, orbit, infratemporal fossa anterior cranial fossa, suggestive malignancy or chronic granulomatous disease. Histopathological examination which was debulked partially excised via endoscopic approach, suggested diagnosis...

Pedunculated polyps of the palatine tonsil are rare benign tumours tonsil. Most cases have been reported in adults with varying presenting symptoms. We report a 12-year-old male child who presented 6 months history difficulty swallowing. There was no breathing difficulty, change voice or trauma. Clinical examination revealed 2x1 cm small pedunculated polyp arising from superior pole right which excised under general anaesthesia. Left normal. A diagnosis fibroepithelial made based on...

Meningiomas are common slow-growing primary central nervous system tumors that arise from the meningothelial cells of arachnoid and spinal cord. Human epidermal growth factor receptor 2 (HER2) or HER2/neu (also known as c-erbB2) is a 185-kD transmembrane glycoprotein with tyrosine kinase activity expressed in meningiomas various other tumors. It can be used targeted therapy for positive meningiomas.To correlate expression protein gender, location, histological subtypes, grade.It was 3½ years...

Papillary cystadenocarcinoma is a rare malignant neoplasm of the salivary gland, characterized by noticeable cystic and solid areas with papillary endophytic projections. These tumours lack features that characterize variants several more common gland carcinomas. It was first described in 1991 World Health Organization as separate entity or without component AFIP classification. Most these occurred major glands followed minor glands. Cystadenocarcinoma counterpart cystadenoma. We report case...

Carcinoma arising in a thyroglossal cyst is rare. We present case of anterior neck swelling diagnosed to be clinically which turns out papillary carcinoma cyst. She underwent sistrunk procedure with total thyroidectomy and diseasefree on follow up evaluation. Even though preoperative ultrasonography had shown thyroid nodule, the final histology did not show malignancy. There paucity clear-cut guidelines management gland carcinoma. In cases, we recommend only when there nodule high-risk features.

Adenocarcinoma is the most common histological type of gastric tumour, accounting for approximately 95% all carcinomas. Gastrointestinal stromal tumours (GISTs) are rare mesenchymal neoplasms digestive tract. Synchronous adenocarcinoma and gastrointestinal tumour (GIST) occurring in stomach very few cases have been reported literature. rarely diagnosed preoperatively. A 63-year-old gentleman was with a on endoscopic biopsy underwent surgery. Postoperative histopathologic examination revealed...

Abstract: Epidermodysplasia verruciformis (EV) is a rare autosomal recessive genodermatosis due to mutations in EVER1 and EVER2 genes. The genetic profile of Indian patients with EV has not been previously studied. This report describes the clinical presentation molecular analysis family EV. Using genomic DNA from two affected probands healthy controls (two other siblings), conventional polymerase chain reaction (PCR) was conducted novel primer sets designed amplify coding splice-site...

e20514 Background: The treatment of metastatic non-small cell lung cancer ( m-NSCLC) is personalized and driven by mutational profiling the tumour tissue at diagnosis. This study evaluates additional clinical utility plasma based molecular testing towards shortening time to initiation detection targetable mutations in a cohort patients with newly diagnosed m-NSCLC. Methods: retrospective analysis advanced NSCLC referred Thoracic Oncology Program between September 2021 December 2023, who...

Cytologic diagnosis of extra‐adrenal paraganglioma presenting as a peripancreatic mass is challenging with high rate diagnostic error. We present case identified by radiology gastrointestinal stromal tumor. Endoscopic ultrasound‐guided fine needle aspiration (FNA) the showed moderately cellular tumor composed small to medium sized neoplastic cells round oval nuclei arranged singly and in loose clusters. The were positive for neuroendocrine markers (synaptophysin chromogranin) negative CD117....

Cytologic diagnosis of extra-adrenal paraganglioma presenting as a peripancreatic mass is challenging, with high rate diagnostic error. We present case identified by radiology gastrointestinal stromal tumor. Endoscopic ultrasound-guided fine-needle aspiration (FNA) the showed moderately cellular tumor composed small-to-medium-sized neoplastic cells round-to-oval nuclei arranged singly and in loose clusters. The were positive for neuroendocrine markers (synaptophysin chromogranin) negative...

Ectomesenchymal chondromyxoid tumour (ECMT) is a rare benign which classically presents in the anterior tongue. This grossly under-reported due to lack of immunohistochemical staining many centres. We report 46-year-old man who presented with mass tongue and was diagnosed ECMT. Further management this lesion explained review literature.

Hypertrophic lichen planus (HLP) is a chronic variant of with an estimated risk 0.4% developing squamous cell carcinoma (SCC) in later years. We report the case 12-year- old boy history hypertrophic since 4 years age, malignant transformation into along lymph node metastasis.

Significance StatementExtranasopharyngeal angiofibromas (ENA) are rare vascular tumors that do not conform to the clinical characteristics of typical nasopharyngeal angiofibromas. We present management an angiofibroma in a site, within frontal sinus with concomitant orbital pyocele, which was completely excised via endoscopic approach. ENAs should be considered as differential diagnosis patients sinonasal mass and epistaxis. Awareness this entity will avoid radical surgery thus decreasing...

A 20-year-old man presented in emergency with fever, abdominal pain and obstipation. On evaluation, he was found to have an acute abdomen septic shock. The cross-sectional imaging revealed hepatosplenomegaly, pleural effusion ascites retroperitoneal lymphadenopathy. He resuscitated started on broad-spectrum antibiotics. There no other source of infection identified elsewhere. While bacterial fungal cultures were negative, the sputum, blood, bone marrow ascitic fluid positive for...

We, herein, present a male neonate with an antenatally detected intra-abdominal cyst who presented at 18 days of life which time, the ultrasound revealed 5×4 cm cyst. Since he was asymptomatic, we planned to repeat month later and operate if showed no regression. However, week later, acute abdomen, irritable cry showing larger (8×6 cm) cystic mass debris within. He taken up for emergency laparotomy. Intraoperatively, found arising from left lateral abdominal wall free all structures twisted...