A5071630707- Sinusitis and nasal conditions
- Head and Neck Surgical Oncology
- Antifungal resistance and susceptibility
- Infectious Diseases and Mycology
- Oral and Maxillofacial Pathology
- Otolaryngology and Infectious Diseases
- Actinomycetales infections and treatment
- Infectious Diseases and Tuberculosis
- Nasal Surgery and Airway Studies
- Ear Surgery and Otitis Media
- Mycobacterium research and diagnosis
- Soft tissue tumor case studies
- Obstructive Sleep Apnea Research
- Allergic Rhinitis and Sensitization
- Fungal Infections and Studies
- Cancer Diagnosis and Treatment
- Advanced Chemical Sensor Technologies
- Tumors and Oncological Cases
- Head and Neck Anomalies
- Tracheal and airway disorders
- COVID-19 Clinical Research Studies
- Olfactory and Sensory Function Studies
- Vascular Anomalies and Treatments
- Neuroscience of respiration and sleep
- Pneumocystis jirovecii pneumonia detection and treatment
Christian Medical College & Hospital
2016-2025
Kamineni Institute of Dental Sciences
2025
Connolly Hospital Blanchardstown
2017-2018
National Postdoctoral Association
2017
This study was performed to assess the risk factors driving epidemic of coronavirus disease 2019 (COVID-19)-associated mucormycosis (COVID–Mucor) in India that has accompanied COVID-19 pandemic, particularly during second wave. Risk were analysed among 164 participants: 132 COVID–Mucor (cases) and 32 non-COVID–Mucor (controls). Data from a prospective cohort over period 1 year used. Diabetes mellitus remained significant factor both groups (97%), while uncontrolled diabetes (odds ratio (OR)...
Assess reliability of oxygen desaturation index (ODI) as an alternative parameter to apnea hypopnea (AHI) in screening patients with severe obstructive sleep (OSA).Retrospectively two-year data on demography, anthropometric features, polysomnography (PSG) parameters [AHI, ODI, minimum saturation (SpO2), mean SpO2], and Epworth sleepiness score (ESS) were collected analyzed.Study showed significant correlation ESS AHI, apnea-hypopnea percentage period time (AH%SPT), SpO2 highest being AHI. A...
Abstract Introduction: Orofacial space infections are potentially fatal and often need emergency medical surgical care. Prompt diagnosis of these can sometimes be difficult because diffuse swelling trismus. Early treatment response is a key to the management recovery. Conventional markers infection, such as C-reactive protein (CRP) white blood cell (WBC) counts fail properly evaluate progress. Procalcitonin (PCT) has high sensitivity specificity for identifying bacterial helps in monitoring....
Posaconazole has significant activity against the Mucormycetes. However, data are limited on clinical efficacy of posaconazole for treating rhino-orbito-cerebral mucormycosis (ROCM). The aim this study is to assess and safety in patients with ROCM. We included 12 consecutive adult admitted ROCM treated between January 2010 February 2015. main outcome was overall success rate (i.e. either complete or partial response) at end treatment. also assessed serum concentrations a subgroup patients....
Abstract Introduction Mucoceles are benign expansile cystic lesions commonly seen in the frontoethmoidal region. Objective To see if distribution of frontal air cells predisposes to mucocele formation. Methods Retrospective review all cases paranasal sinus from 2011 2021. Data on demographics, history surgery or trauma, clinical features, radiological findings, and outcome were collected analyzed. Results Of 28 cases, 19 (67.9%) male 9 (32.1%), female, with a mean age 40.75 years. Mucocele...
To evaluate the efficacy and safety of short-course intravenous amphotericin B followed by sustained release posaconazole tablets for diabetes or COVID-19-associated rhino-orbito-cerebral mucormycosis.This prospective, pragmatic study included adults with mucormycosis. Patients received short (7-14 days) long (15-28 antifungal therapy (short treatment [SHIFT] [LIFT], respectively) depending on presence absence brain involvement. All patients step-down tablets, debridement, glycemic control....
Abstract Objective: To assess the efficacy of dynamic slow motion video endoscopy as a test eustachian tube function based on its correlation with swallow test. Method: The and were performed 100 clinically normal middle ears adults undergoing rigid nasal for various indications. findings interpreted by three observers who blind to results test, both techniques compared. Results: There was statistically significant between some more lenient criteria. Five tubes had floppy medial...
In order to study the bacteriological profile, antibiotic sensitivity and outcome following empirical therapy with early generation antibiotics in patients deep head neck infection, a retrospective review of 42 admitted for drainage intravenous was performed. Ludwig's angina commonest most common organisms isolated being Group F ß-haemolytic (15%) non-haemolytic (12.5%) streptococcus. All streptococci anaerobic gram-positive cocci were susceptible penicillin. S. aureus isolates...
The aim of this study was to clarify the contentious taxonomic classification Rhinosporidium seeberi, cause human rhinosporidiosis, which may have treatment implications.PCR used amplify internal transcribed spacer (ITS)-2 region from genomic DNA aetiological agent obtained a sample rhinosporidiosis lesions. amplicon sequenced and organism identified using Basic Local Alignment Search Tools (BLAST).Phylogenetic analysis revealed that clustered along with R. seeberi isolated humans also...
Sinonasal organising haematoma is a recently described, rare, benign inflammatory condition, which closely resembles malignancy in its clinical presentation.To describe the features of and to review evolution surgical options successfully used.A retrospective charts all patients with histopathological diagnosis sinonasal was performed.Six (60%) 10 were male mean age 47.4 years. All had unilateral disease recurrent epistaxis as presenting symptom. Maxillary sinus most commonly involved sinus....
Acute lingual swelling is a potentially life threatening clinical condition which encountered very rarely, the differential diagnosis of includes hemorrhage, infarction, abscess, tumor and edema. Herein we report case abscess that presented with acute tongue respiratory distress after extraction lower two incisor teeth.
Angioleiomyomas are infrequent benign tumors originating from smooth muscle cells of arterial or venous walls. They most commonly seen in the lower extremities with a prevalence only 8.5% head and neck. We present case 40-year-old male patient who presented to Christian Medical College, Vellore, India, recurrent episodes right-sided epistaxis. A computed tomography scan showed an enlarged right inferior turbinate filling nasal cavity. The mass was removed endoscopically sent pathology....
Rhinosporidiosis is a chronic granulomatous disease of the nose caused by Rhinosporidium seeberi. The largely non-amenable to medical therapy and shows high recurrence rates requiring patients undergo multiple surgeries often resulting in increased morbidity.To analyse epidemiological, clinical, histopathological characteristics, treatment outcome rhinosporidiosis identify factors which predispose disease.Retrospective analysis data all with diagnosis confirmed histopathology at tertiary...
Bilateral paranasal sinus mucoceles are rare. To date, only 5 cases have been reported in the English-language literature. All were bilaterally symmetrical. We present a patient with bilateral asymmetric mucoceles. This had symptomatic mucocele of right ethmoid orbital extension and an asymptomatic involving left maxillary retroorbital extension. The latter was incidental finding on radiologic evaluation. is first case report involvement sinuses.
Objective: To describe the diagnosis and management of an unusual case solitary fibrous tumor nasal cavity. Methods:The records a patient with cavity were reviewed.Results: This presented constant obstruction one half years duration.Nasal endoscopy revealed firm polypoidal mass filling left medial to middle turbinate.After imaging, she underwent endoscopic excision which on histopathological examination was diagnosed as tumor.At follow up after year, there no recurrence tumour....
Rhino-orbito-cerebral-mucormycosis (ROCM), a rare and potentially fatal disease was seen in increasing numbers during the COVID-19 pandemic. This study describes compares patient characteristics outcomes associated mucormycosis (CAM) non-COVID-19 (non-CAM).CAM patients (24 cases) were recruited from period non-CAM controls) pre-COVID-19 period. Clinical data of CAM group collected retrospectively with 3 month prospectively. The retrospectively. Patient compared risk factors for mortality...
Aim: To assess the need for nasal packing following functional endoscopic sinus surgery (FESS) chronic rhinosinusitis (CRS). Materials and methods:We used a prospective, singleblinded, intrapatient, randomized, controlled study design.Fifty patients undergoing bilateral FESS were randomized to have on one side day no other.Postoperative bleeding, block, facial pain, headache monitored 5 days.Improvement of symptoms sino-nasal outcome test (SNOT)-22 scores at 4th 12th postoperative weeks...