- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Cardiac Valve Diseases and Treatments
- Coronary Artery Anomalies
- Mechanical Circulatory Support Devices
- Infective Endocarditis Diagnosis and Management
- Ultrasound in Clinical Applications
- Venous Thromboembolism Diagnosis and Management
- Congenital Anomalies and Fetal Surgery
- Pericarditis and Cardiac Tamponade
- Cardiac Imaging and Diagnostics
- Tracheal and airway disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Pulmonary Hypertension Research and Treatments
- Cardiac Arrhythmias and Treatments
- Colonialism, slavery, and trade
- Cardiovascular and Diving-Related Complications
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Issues in Pregnancy
University of Zurich
2017-2024
University Children's Hospital Zurich
2023-2024
University Hospital of Zurich
2019-2023
Newcastle upon Tyne Hospitals NHS Foundation Trust
2022
Freeman Hospital
2019-2022
Minneapolis Heart Institute Foundation
2020
Zurich Heart House
2017
AimsTo determine the prevalence of baffle leaks in adults after atrial switch operations for transposition great arteries, as these may predispose to paradoxical embolic events, particularly patients with transvenous pacemaker or defibrillator leads.
BACKGROUND In 2013, a prospective registry for adults with congenital heart disease (CHD) was established in Switzerland, providing detailed data on characteristics and outcomes: Swiss Adult Congenital HEart Registry (SACHER). Its aim is to improve the knowledge base of outcomes CHD. The design baseline patient are reported. METHODS All patients structural defects or hereditary aortopathies, followed-up at dedicated adult CHD clinics, asked participate SACHER. Data participants pseudonymised...
Fontan-associated liver disease is an increasing concern. Our aim was to assess prevalence and predictors of advanced fibrosis with a specific focus on utility stiffness measurement by ultrasound transient elastography.A total 97 adult Fontan patients (55% male, median age: 23.1 years, interquartile range [IQR]: 18.7-30.6); 92 (95%) were evaluated elastography, 50 (52%) underwent transjugular biopsy. Advanced defined as congestive hepatic score 3 or 4.Only 4 (4%) had values < 10 kilopascal...
Ventricular assist device (VAD) for systemic right ventricular (RV) failure patients post-atrial switch, transposition of the great arteries (TGA), and those with congenitally corrected TGA has proven useful to reduce transpulmonary gradient bridge-to-transplantation. The purpose this study is describe our experience VAD in RV move towards concomitant tricuspid valve replacement (TVR).This a single-centre retrospective consecutive adult receiving HeartWare between 2010 2019. From 2017, TVR...
BACKGROUND Population based studies show a steady increase in adult patients with congenital heart defects. The aim of this study was to assess the evolution such patient cohort and its burden on clinical care at dedicated tertiary centre. METHODS All disease followed up by multidisciplinary team our institution were identified (n = 1725). Disease characteristics, numbers interventions selected complications analysed compared between first (1996–2005) second (2006–2015) decades period....
Our aim was to assess changes of right ventricular end-diastolic volumes (RVEDVi) and ejection fraction (RVEF) in asymptomatic adults with repaired tetralogy Fallot, native outflow tract severe pulmonary regurgitation by serial cardiac magnetic resonance imaging (CMR). The study included 23 who underwent ≥3 CMR studies (total 88 studies). We compared RVEDVi RVEF between first last (median follow-up: 8.8 years, interquartile range: 6.3 13.1 years) all pairs. Variability measurements pairs (65...
Infective endocarditis is a major threat after prosthetic pulmonary valve replacement. Early diagnosis may improve outcomes.A structured patient education programme for prevention and early of infective was developed at our institution since 2016. Time delay between onset symptoms its (defined as initiation appropriate high-dose intravenous antibiotic treatment) compared patients presenting before (cohort 1) 2) the programme.Between 2008-2019, 26 (median age 24.9, range: 16.8-62.0 years, 73%...
Introducción y objetivos: Evaluar el impacto del recambio de válvula pulmonar (RVP) en pacientes con tetralogía Fallot reparada (TFr) la evolución los volúmenes función biventricular eventos adversos. Métodos: Se identificó a adultos TFr registro SACHER. evaluaron datos seriados cardiorresonancia magnética, ecocardiografía, capacidad ejercicio fracción aminoterminal propéptido natriurético cerebral (NT-proBNP). El objetivo primario fue eyección ventrículo derecho (FEVD) medida por...
Introduction and objectives: Our aim was to assess the impact of prosthetic pulmonary valve replacement (PVR) in patients with repaired tetralogy Fallot (rTOF) on changes biventricular volumes function adverse cardiac events. Methods: Adults rTOF were identified from SACHER-registry. Data serial magnetic resonance imaging, echocardiography, exercise capacity n-terminal pro b-type natriuretic peptide (NT-proBNP) collected. The primary endpoint right ventricular ejection fraction (RVEF) as...
Este livro insere-se num campo historiografico a que se poderia chamar uma historia economica da Inquisicao, claramente das linhas de trabalho menos exploradas na massa historiografica dedicada aos tribunais inquisitoriais. Trata-se versao em lingua inglesa, com poucas alteracoes substanciais, obra originalmente publicada italiano (I denari dell’inquisitore: affari e giustizia di fede nell’Italia moderna. Torino: G. Einaudi, 2014). O proposito do seu autor, Germano Maifreda –...