About
Contact & Profiles
A5012755756
Research Areas
- T-cell and B-cell Immunology
- Cell Adhesion Molecules Research
- CAR-T cell therapy research
- Immune Cell Function and Interaction
University of Cambridge
2021-2022
The integrin lymphocyte function–associated antigen 1 (LFA-1) helps to coordinate the migration, adhesion, and activation of T cells through interactions with intercellular adhesion molecule (ICAM-1) ICAM-2. LFA-1 is activated during engagement chemokine receptors cell receptor (TCR) inside-out signaling, a process that partially mediated by phosphoinositide 3-kinase (PI3K) its product phosphatidylinositol 3,4,5-trisphosphate (PIP 3 ). To evaluate potential roles PI3K in activation, we...
10.1126/scisignal.abl9169
article
EN
Science Signaling
2022-07-19
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