Abstract Self-assembly provides access to a variety of molecular materials, yet spatial control over structure formation remains difficult achieve. Here we show how reaction–diffusion (RD) can be coupled self-assembly process generate macroscopic free-standing objects with shape, size, and functionality. In RD, two or more reactants diffuse from different positions give rise spatially defined structures on reaction. We demonstrate that RD used locally hydrazone gelators their non-assembling...

Hydrogel microparticles are important in materials engineering, but their applications remain limited owing to the difficulties associated with manipulation. Herein, we report self-orientation of crescent-shaped hydrogel and elucidate its mechanism. Additionally, were used, for first time, as micro-buckets carry living cells. In aqueous solution, spontaneously rotated a preferred orientation cavity facing up. We developed geometric model that explains self-orienting behavior particles by...

We report the continuous production of microcapsules composed an aqueous core and permeable hydrogel shell, made stable by controlled photo-cross-linking shell all-aqueous double emulsion.

In this contribution we show that biological membranes can catalyze the formation of supramolecular hydrogel networks. Negatively charged lipid generate a local proton gradient, accelerating acid-catalyzed hydrazone-based gelators near membrane. Synthetic be used to tune physical properties resulting multicomponent gels as function concentration. Moreover, catalytic activity and gel networks around these structures are controlled by charge phase behavior molecules. Finally, insights obtained...

Abstract A generic method is used for compartmentalization of supramolecular hydrogels by using water‐in‐water emulsions based on aqueous multi‐phase systems (AMPS). By forming the low‐molecular‐weight hydrogel throughout all phases all‐aqueous emulsions, distinct, micro‐compartmentalized materials were created. This structuring approach offers control over composition each type compartments directing partitioning objects to be encapsulated. Moreover, this allows barrier‐less, dynamic...

The use of polymeric crosslinkers is an attractive method to modify the mechanical properties supramolecular materials, but their effects on self-assembly underlying polymer networks are poorly understood. Modulation gelation pathway a reaction-coupled low molecular weight hydrogelator demonstrated using (bio)polymeric disparate physicochemical identities, providing handle for control over materials properties. As service our authors and readers, this journal provides supporting information...

Abstract Hydrogel microparticles are important in materials engineering, but their applications remain limited owing to the difficulties associated with manipulation. Herein, we report self‐orientation of crescent‐shaped hydrogel and elucidate its mechanism. Additionally, were used, for first time, as micro‐buckets carry living cells. In aqueous solution, spontaneously rotated a preferred orientation cavity facing up. We developed geometric model that explains self‐orienting behavior...

Abstract A generic method is used for compartmentalization of supramolecular hydrogels by using water‐in‐water emulsions based on aqueous multi‐phase systems (AMPS). By forming the low‐molecular‐weight hydrogel throughout all phases all‐aqueous emulsions, distinct, micro‐compartmentalized materials were created. This structuring approach offers control over composition each type compartments directing partitioning objects to be encapsulated. Moreover, this allows barrier‐less, dynamic...

Abstract We report a flexible single-cell isolation method by imaging-assisted hydrogel formation. Our approach consists of imaging-aided selective capture cells interest encasing them into polymeric hydrogel, followed removal unwanted and subsequent release isolated enzymatic degradation, thus offering an opportunity for further analysis or cultivation selected cells. achieved high sorting efficiency observed excellent viability rates (>98%) NIH/3T3 fibroblasts A549 carcinoma using this...

Reported here is a 2D, interfacial microcompartmentalization strategy governed by 3D phase separation. In aqueous polyethylene glycol (PEG) solutions doped with biotinylated polymers, the polymers spontaneously accumulate in layer between oil-surfactant-water interface and adjacent polymer phase. two-phase systems, these first accumulated separating two then selectively migrated to oil-PEG layer. By using varying photopolymerizable groups crosslinking rates, kinetic control capture of...

The last decade has witnessed great progress in understanding and manipulating self-assembly of block copolymers solution. A wide variety micellar structures can be created many promising applications bioscience have been reported. In particular, nano-fibrous micelles provide a platform to mimic the filamentous structure native extracellular matrix (ECM). However, evaluation this kind filomicellar system with potential use tissue engineering is virtually unexplored. question behind it, such...

Cyclization of 2-dimethylaminomethylene-1,3-bis(di­methylimonio)propane diperchlorate with various amino heterocycles led to the formation a series fused heterocyclic systems containing 3-formylpyridine or 5-formylpyrimidine unit.

Abstract Cyclocondensation of a variety amino heterocycles with the trisformylmethane synthon (II) offers useful access to title compounds in varying yields.

Sich selbst ausrichtende Hydrogel-„Mikroeimer” wurden entwickelt und zum Transport lebender Zellen genutzt. J. H. van Esch et al. zeigen in ihrer Zuschrift auf S. 557 ff. die Selbstorientierung halbmondförmiger Hydrogelmikropartikel klären ihren Mechanismus auf. Die Mikropartikel auch als Zelltransporter für Zellbeladung, -transport, -proliferation -freisetzung vitro verwendet.

Die Kompartmentierung von Hydrogelen die J. H. van Esch et al. in ihrer Zuschrift auf S. 15119 vorstellen, nutzt Inkompatibilität wässriger Polymerlösungen zur Bildung Mikrodomänen im Gerüst eines supramolekularen Hydrogels. Strategie verzichtet hydrophobe Barrieren und ermöglicht es, Domänenzusammensetzung vorzugeben, sodass neuartige strukturierte Materialien erzeugt werden können.

Abstract Reported here is a 2D, interfacial microcompartmentalization strategy governed by 3D phase separation. In aqueous polyethylene glycol (PEG) solutions doped with biotinylated polymers, the polymers spontaneously accumulate in layer between oil‐surfactant‐water interface and adjacent polymer phase. two‐phase systems, these first accumulated separating two then selectively migrated to oil‐PEG layer. By using varying photopolymerizable groups crosslinking rates, kinetic control capture...