A5087221112- Glioma Diagnosis and Treatment
- Muscle Physiology and Disorders
- Epilepsy research and treatment
- Botulinum Toxin and Related Neurological Disorders
- Long-Term Effects of COVID-19
- Neurogenetic and Muscular Disorders Research
- Neonatal and fetal brain pathology
- Attention Deficit Hyperactivity Disorder
- Peripheral Neuropathies and Disorders
- Pain Mechanisms and Treatments
- Inflammatory Myopathies and Dermatomyositis
- Neuroscience of respiration and sleep
- Hereditary Neurological Disorders
- Electrochemical sensors and biosensors
- Child Nutrition and Feeding Issues
- Metabolism and Genetic Disorders
- Carbon and Quantum Dots Applications
- Epigenetics and DNA Methylation
- Mitochondrial Function and Pathology
- Cancer-related gene regulation
- COVID-19 and healthcare impacts
- Myasthenia Gravis and Thymoma
- Diversity and Career in Medicine
- Skin Diseases and Diabetes
- Peripheral Nerve Disorders
King Abdulaziz University
2018-2025
Taibah University
2025
National Guard Health Affairs
2025
Armed Forces Hospital
2025
University of Tabuk
2025
Qassim University
2025
King Abdulaziz Hospital
2020-2024
King Faisal Specialist Hospital & Research Centre
2021-2024
University of Jeddah
2024
King Fahd Medical City
2024
Coronavirus disease (COVID-19) is caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Physicians in China reported what believed to be the first adult case of a SARS-CoV-2 associated Guillain-Barré (GBS), followed 5 Italian patients and another United States. In current report, we present one descriptions an association GBS child. our facility, 11-year-old boy presented typical features and, after days, morbilliform skin rash over palms both hands. Three...
An environmentally friendly N-CQDs-based fluorescence sensor for gabapentin detection is developed, with optimal conditions and high selectivity, accuracy, precision in real sample analysis.
The COVID-19 pandemic poses unprecedented challenges to healthcare workers worldwide. This study sought estimate the prevalence of depression, anxiety, and stress among in Saudi Arabia, identify factors associated with these psychological disorders.
Autism spectrum disorder (ASD) affects approximately 1.4% of the population and imposes significant social economic burdens. Because its etiology is unknown, effective diagnosis challenging. Advancements in structural magnetic resonance imaging (sMRI) allow for objective assessment ASD by examining brain changes. Recently, machine learning (ML)-based diagnostic systems have emerged to expedite enhance process. However, expected success was not yet achieved. This study evaluates compares...
Background and objective Breath-holding spells (BHS) are common in infants young children, often triggered by emotional factors like anger or frustration. While their exact cause remains unknown, potential causative include iron deficiency delayed brain development. Despite frequency, many parents lack proper awareness understanding of BHS. This study assessed parental knowledge BHS among Saudi Arabian toddlers. Methods A cross-sectional was conducted using an online questionnaire from...
A BSTRACT Background: Empathy plays a vital role in optimizing care, demanding its presence both clinicians and patients within the pediatric context. In this domain, empathy takes on multidimensional aspect, considering various cognitive subdimensions. Moreover, families’ sensitivity have been identified as potent protective factors influencing psychosocial adjustment. Objectives: The study was designed to assess level of among parents attending neurology clinics. Methods: This is...
SEPN1-related myopathies (SEPN1-RM) encompass a rare subset of neuromuscular disorders stemming from mutations in the SELENON gene. Here, we present case 15-year-old Saudi child harboring an autosomal recessive homozygous c.2T>A. (chr1:25800232 T>A) (NM_020451.3), exhibiting distinct clinical profile hypotonia, motor delay, muscle weakness, scoliosis, and sleep apnea. Advanced genetic testing revealed additional heterozygous variants CNGA1 BTD genes. Our report underscores complexity...
Introduction COVID-19 has been a gravitating topic in the past months, yet much information about this new virus is to be unraveled. The uncertainties and its effects have affected lot of daily life activities. One these activities emergency department (ED) visits how disease might changed people's perspective on when go an emergency. This study aims assess effect pandemic for neurological conditions. Methods A retrospective record review was conducted at King Abdul-Aziz University Hospital...
Abstract Background Guillain–Barre syndrome (GBS) is an inflammatory polyradiculoneuropathy characterized by rapidly evolving weakness and areflexia, reaching nadir within 4 weeks. Data on the characteristic of GBS in Saudi Arabia are limited. This study aimed to describe clinical, electrophysiological, laboratory characteristics outcome a multicenter cohort patients with GBS. Methods retrospective nationwide study. Patients who had GBS, identified through Brighton Criteria, between January...
Abstract Objectives Protein Arginine Methyltransferase 5 ( PRMT5 ) is an enzyme that regulates gene expression and protein function through arginine methylation. Its association with isocitrate dehydrogenase (IDH) mutation in Grade-4 astrocytoma was rarely investigated. Our aim to explore the between IDH its effect on tumor recurrence. Methods A retrospective cohort of 34 patients Grade 4 has been tested for using arrays. The impact IDH-mutation recurrence explored. Results IDH-wildtype...
Osama Y. Muthaffar, Ahmed K. Bamaga, Anas S. Alyazidi, Layan Baaishrah, Hussain A. Alkhalifah, Rafah B. Hariri, Maya Khider, Sereen Alahmadi
Background Drug-resistant epilepsy (DRE) impacts a significant portion, one-third, of individuals diagnosed with epilepsy. In such cases, exploring non-pharmacological interventions are crucial, the ketogenic diet (KD) standing out as valuable option. KD, high-fat and low-carb dietary approach roots dating back to 1920s for managing DRE, triggers formation ketone bodies modifies biochemistry aid in seizure control. Recent studies have increasingly supported efficacy KD addressing showcasing...
Background: The coronavirus disease 2019 (COVID-19) pandemic has caused overwhelming challenges in healthcare worldwide. During such an outbreak, some needs of high-risk groups who require regular follow-ups and long-term management are not met. vulnerable populations include patients with Duchenne muscular dystrophy (DMD). is characterized by respiratory complications muscle weakness. Hence, this condition at high risk severe diseases including COVID-19. Methods: To standardize care provide...
Novel Severe Acute Respiratory Syndrome-Corona Virus-2 infection (SARS-CoV-2) is an acute respiratory and infectious disease. This perspective aims to provide a basic understanding of the inflammation caused by SARS-CoV-2 its relation trigeminal ganglion (TG). The virus enters through mucous membranes orofacial region reaches TG, where it resides takes control peptides including Substance P (SP). SP main neuropeptide, neuromodulator, neuro-hormone associated with nociception under noxious...
Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) causes disease 2019 (COVID-19), which became a pandemic in late and early 2020. Apart from many other symptoms of this infection, such as loss smell taste, rashes, body aches, fatigue, psychological cardiac symptoms, it also vasodilation response to inflammation via nitric oxide release. SARS CoV-2 affects microcirculation, resulting the swelling damage endothelial cells, micro thrombosis, constriction capillaries, pericytes that...
Brown-Vialetto-Van Laere syndrome (BVVL) is a rare, progressive neurodegenerative disease with fewer than 100 cases reported in the literature. It characterized by pontobulbar palsy and sensorineural hearing loss.1 The age at onset varies from infancy to early adulthood, commonly presenting cranial nerve VII–XII palsies deafness. Other findings include gait ataxia, limb weakness, optic atrophy, epilepsy, respiratory compromise.1 genetic etiology of BVVL has recently been linked mutations...
Background Spinal muscular atrophy (SMA) is a rare debilitating condition with significant burden for patients and society. However, little known about how it affects Saudi Arabia's population. The socioeconomic medical characteristics of affected SMA their caregivers are lacking. Purpose This study aimed to describe the in Arabia. Patients methods A cross-sectional questionnaire-based was conducted using snowball sampling. Assessment tools including EuroQol (EQ-5D-5L) visual analog scale...