Pierre Bertholon

ORCID: 0000-0002-0126-2374
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About
Contact & Profiles
Research Areas
  • Vestibular and auditory disorders
  • Ear Surgery and Otitis Media
  • Hearing, Cochlea, Tinnitus, Genetics
  • Ophthalmology and Eye Disorders
  • Cerebral Venous Sinus Thrombosis
  • Glaucoma and retinal disorders
  • Facial Nerve Paralysis Treatment and Research
  • Congenital Ear and Nasal Anomalies
  • Vector-borne infectious diseases
  • Ear and Head Tumors
  • Meningioma and schwannoma management
  • Mosquito-borne diseases and control
  • Migraine and Headache Studies
  • Otitis Media and Relapsing Polychondritis
  • Spatial Cognition and Navigation
  • Cerebrospinal fluid and hydrocephalus
  • Cardiovascular Syncope and Autonomic Disorders
  • Head and Neck Anomalies
  • Spinal Dysraphism and Malformations
  • Herpesvirus Infections and Treatments
  • Neurotransmitter Receptor Influence on Behavior
  • Neurofibromatosis and Schwannoma Cases
  • Glycogen Storage Diseases and Myoclonus
  • Epilepsy research and treatment
  • Virtual Reality Applications and Impacts

Centre Hospitalier Universitaire de Saint-Étienne
2013-2024

Hôpital Nord
1997-2021

Institute Cancer De La Loire Lucien Neuwirth
2018

Hôpital Pasteur
1996-2009

Bellevue Hospital Center
1993-2004

National Hospital for Neurology and Neurosurgery
2000

University College London
2000

Nagoya University
1996

Aichi Medical University
1996

Hiroshima University
1996

Certain patients with balance disorders report a `visual vertigo' in which their symptoms are provoked or aggravated by specific visual contexts (e.g. supermarkets, driving movement of objects). In order to determine the causes vertigo (VV), we assessed symptoms, anxiety and influence disorienting stimuli 21 such patients. 17 out patients, peripheral vestibular disorder was diagnosed. Sixteen bilateral labyrinthine-defective subjects (LDS) 25 normal served as controls. Questionnaire...

10.1093/brain/124.8.1646 article EN Brain 2001-08-01

Objectives: To clarify the clinical significance of positional down beat nystagmus (pDBN). Methods: A discussion neuro-otological findings in 50 consecutive patients with pDBN. Results: In 38 there was evidence CNS disease (central group) but 12 not (idiopathic group). group, presenting symptoms were gait, speech, and autonomic dysfunction whereas idiopathic group mostly reported vertigo. The main neurological oculomotor signs explained by cerebellar dysfunction, including 13 multiple system...

10.1136/jnnp.72.3.366 article EN Journal of Neurology Neurosurgery & Psychiatry 2002-03-01

<i>Objective:</i> The pathogenesis of idiopathic sudden sensorineural hearing loss (ISSHL) remains unknown, but vascular involvement is one the main hypotheses. objective this study was to investigate association between ISSHL and cardiovascular thromboembolic risk factors. <i>Study Design:</i> Multicentric case-control study. <i>Methods:</i> Ninety-six Caucasian patients with 179 sex- age-matched controls were included. Patients evaluated on day inclusion...

10.1159/000312640 article EN Audiology and Neurotology 2010-06-10

This paper presents diagnostic criteria for vascular vertigo and dizziness as formulated by the Committee Classification of Vestibular Disorders Bárány Society. The classification includes vertigo/dizziness due to stroke or transient ischemic attack well isolated labyrinthine infarction/hemorrhage, vertebral artery compression syndrome. Vertigo are among most common symptoms posterior circulation strokes. Vascular may be acute prolonged (≥24 hours) (minutes < 24 hours). should considered...

10.3233/ves-210169 article EN other-oa Journal of Vestibular Research 2022-04-01

The purpose of this study was to investigate the various diagnoses patients who present with positional nystagmus.Positional maneuvers were systematically performed in plane posterior canal (PC; Dix-Hallpike maneuver) and horizontal (HC; rolled either side a supine position) on 490 consecutive essentially referred for vertigo and/or gait unsteadiness.One hundred (20%) presented nystagmus. This nystagmus had peripheral origin 83 patients, including 80 benign paroxysmal (BPPV). In BPPV, PC...

10.1177/000348940611500804 article EN Annals of Otology Rhinology & Laryngology 2006-08-01

Introduction: An increased number of otic capsule dehiscence (OCD) variants relying on the third window pathomechanism have been reported lately. Therefore, a characterization anatomical structures involved and an accurate radiological description (TW) interface location become essential for improving diagnosis appropriate therapeutic modalities. The purpose this article is to propose classification based clinical, anatomical, data mobile abnormalities (TMWA) discuss alleged in lesser-known...

10.3389/fneur.2021.792545 article EN cc-by Frontiers in Neurology 2022-01-11

Objective: To describe aspects in clinical and genetic presentation five patients with episodic ataxia type 2 (EA2). Methods: CACNA1A gene screening identified a mutation three probands two of their children. Results: The had attacks imbalance, associated dizziness/vertigo and/or headache. Two them independent migraine attacks. Interictal oculomotor examination revealed gaze evoked nystagmus central signs. history strabismus. All responded well to acetazolamide. children were found have both...

10.1136/jnnp.2008.159103 article EN Journal of Neurology Neurosurgery & Psychiatry 2009-10-28

We report 3 patients who complained of positional vertigo shortly after head trauma. Positional maneuvers performed in the plane posterior canal (PC; Dix-Hallpike maneuver) and horizontal (HC; were rolled to either side a supine position with raised 30°) revealed complex nystagmus that could only be interpreted as result combined PC HC benign paroxysmal (BPPV). Two had right BPPV an ageotropic BPPV, 1 patient bilateral left geotropic BPPV. All rapidly free was cured by Epley maneuver...

10.1177/000348940511400204 article EN Annals of Otology Rhinology & Laryngology 2005-02-01

10.1016/j.anorl.2018.10.007 article EN European Annals of Otorhinolaryngology Head and Neck Diseases 2018-10-25

Objectives: Previous studies demonstrated that otosclerosis diagnosis benefits from temporal bone density measurements. We sought to assess measurements of the fissula ante fenestram (FAF) in normal patients, patients with otosclerosis, and cholesteatoma. discuss value who have a normal-appearing computed tomographic (CT) scan. Methods: This was prospective case-control study which 219 bones (123 adults, 18 84 years age) were included between November 1, 2002, April 30, 2004. All underwent...

10.1177/000348940711600306 article EN Annals of Otology Rhinology & Laryngology 2007-03-01

Absence of the round window as a congenital defect is rare entity that causes conductive hearing loss. To best our knowledge, isolated and nonsyndromal absence has only been reported 3 times; diagnoses were made during surgery. We are reporting on another case was diagnosed before operation by virtual endoscopy middle ear high-resolution computed tomography scan. Although this new technique requires further validation, it may be an alternative to surgery means confirming diagnosis.

10.1177/000348940211100907 article EN Annals of Otology Rhinology & Laryngology 2002-09-01

This study analyzes the morphological and hearing results obtained from intact canal wall cholesteatoma surgery by removing malleus, reinforcing whole tympanic membrane with cartilage, performing an ossiculoplasty a hydroxyapatite prosthesis. The were compared to those in preserving malleus manubrium, partially predominantly using ossicle perform ossiculoplasty. One- or two-stage procedures performed 390 adult patients (416 ears) who had nonoperated middle ear cholesteatoma. Recurrent...

10.1177/000348940411300601 article EN Annals of Otology Rhinology & Laryngology 2004-06-01

We report a 25-year-old man with Creutzfeldt-Jakob disease (CJD) who had received dura mater embolization in the external carotid artery for nasopharyngeal angiofibroma 90 months earlier. The patient was heterozygotous (Met/Val) at codon 129. This case suggests that can be responsible CJD.

10.1212/wnl.48.5.1451 article EN Neurology 1997-05-01

Objective: The purpose of this study was to assess the value virtual endoscopy (VE) in diagnosis lesions ossicular chain and compare two-dimensional (2D) spiral computed tomography (CT) data. Study Design: Retrospective study. Setting: A university hospital. Patients: Fifty-eight patients with suspected underwent a high-resolution CT temporal bone both 2D data VE before surgery. Main Outcome Measures: Two views were chosen for VE. obtained (2D, VE, VE) compared noted during Results: In...

10.1097/00129492-200405000-00002 article EN Otology & Neurotology 2004-04-30

Our data prove that lasers are safe and useful instruments in stapes surgery. Good postoperative results can be attained both KTP Er: YAG lasers. There was no significant inner ear damage related to the laser use.To compare of stapedotomies performed with Erbium: patients otosclerosis order assess risk for ear.The charts 152 consecutive adult who underwent primary from 1999 2005 were reviewed. One hundred thirty-seven (98 patients) using 54 (54 laser. All separated two groups according type...

10.1080/00016480802179727 article EN Acta Oto-Laryngologica 2008-06-20

10.1016/j.anorl.2011.10.009 article EN publisher-specific-oa European Annals of Otorhinolaryngology Head and Neck Diseases 2012-03-16
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