A5064855121- Voice and Speech Disorders
- Tracheal and airway disorders
- Head and Neck Cancer Studies
- Thyroid and Parathyroid Surgery
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Anomalies
- Head and Neck Surgical Oncology
- Dysphagia Assessment and Management
- Nerve Injury and Rehabilitation
- Ear and Head Tumors
- Vascular Anomalies and Treatments
- Parathyroid Disorders and Treatments
- Sinusitis and nasal conditions
- Airway Management and Intubation Techniques
- Vestibular and auditory disorders
- Peripheral Nerve Disorders
- Migraine and Headache Studies
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging Techniques and Applications
- Esophageal and GI Pathology
- Vascular Malformations and Hemangiomas
- Olfactory and Sensory Function Studies
- Ear Surgery and Otitis Media
- Cancer Diagnosis and Treatment
- Cleft Lip and Palate Research
Centre Hospitalier Universitaire de Saint-Étienne
2010-2023
Université Jean Monnet
2014-2023
Institute Cancer De La Loire Lucien Neuwirth
2013-2023
Hôpital Nord
2009-2021
Biologie, ingénierie et imagerie pour l'Ophtalmologie
2014-2021
Universidad de Valladolid
2020
Despite immune microenvironment of head and neck squamous cell carcinoma (HNSCC) has been studied, there are no sufficient data on the role tumor stroma factors. The aim study was to explore prognostic predictive these factors in a large series HNSCC.This is retrospective 266 patients with laryngeal pharyngeal SCC. Clinical were correlated following histological parameters: tumor-stroma ratio (TSR), budding activity (BA), nests size (CNS), type.Stroma-rich tumors, budding, smaller CNS at...
Sinonasal undifferentiated carcinoma (SNUC) is a very rare entity with poor prognosis. Due to the lack of studies on subject, evidence lacking concerning its management.A multicenter collaborative study was conducted assess treatment strategy, oncological outcome, and prognostic factors.Definitive analyses focused 54 patients majority advanced stage; 3-year overall survival (OS) recurrence-free (RFS) rates were, respectively, 62.4% 47.8%. During follow-up, 18 (33.3%) died, 10 (18.5%)...
Induction chemotherapy (IC) is occasionally used in head and neck cancer, leading to less extensive surgery reduced need for irradiation. Factors predicting the response IC have not been determined. In this study, we investigated clinical histopathologic factors that predict IC.Head squamous cell carcinomas from 81 patients were analyzed; factors, histologic parameters, expression of p16 p53 correlated with prognosis.Factors a good nonoropharyngeal localization, rich lymphocytic tissue...
Staphylococcus aureus is able to invade mammalian cells during infection and was recently observed inside nasal mucosa of healthy carriers.To determine the intracellular activity antimicrobial compounds used for decolonization procedures using a cell model mimicking S. epithelium invasion.HaCaT human epithelial (HNECs) recovered from swabs carriers were visualized by confocal laser scanning microscopy detect cells. An HaCaT model, internalization ex vivo in HNECs, assess against 21...
Conclusion: Human papillomavirus (HPV) infection, especially by HPV 16, is frequently detected in oropharyngeal squamous cell carcinoma (OSCC). The expression of viral oncoproteins tumoral tissues OSCCs suggests the implication tumorogenesis. It should now be systematically and considered each patient's treatment outcome. Objectives: To investigate prevalence oncogenic role patients from South-East France with head neck (HNSCC), resulting clinical implications. Methods: Biopsy samples 200...
<b><i>Aim:</i></b> To demonstrate the surgical technique and results in patients operated on with a preauricular transmandibular transzygomatic approach. <b><i>Methods:</i></b> This was used 21 benign malignant tumors of infratemporal fossa (ITF), between 1999 2011. <b><i>Results:</i></b> Twenty-one were enrolled study. There 6 15 ones. No lesions show any disease recurrence 5 years after surgery present excellent...
In metastatic head and neck squamous cell carcinoma (HNSCC) the tumor does not always keep same gene expression profile as parental tumor, which may influence course of disease. The aim this study was to compare genes implicated in HNSCC carcinogenesis between primary corresponding lymph node metastasis.Eighteen HNSCC, their metastases non-neoplastic tissues were studied by RT-qPCR for EGFR, VEGF, claudin7, maspin, survivin SCCA. levels correlated with histological characteristics patients'...