P. Berthelot

ORCID: 0000-0001-9356-8081
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About
Contact & Profiles
Research Areas
  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Antimicrobial Resistance in Staphylococcus
  • Antibiotic Resistance in Bacteria
  • Bacterial biofilms and quorum sensing
  • Drug-Induced Hepatotoxicity and Protection
  • Healthcare Systems and Practices
  • Drug Transport and Resistance Mechanisms
  • Nosocomial Infections in ICU
  • Neonatal Health and Biochemistry
  • Metabolism and Genetic Disorders
  • Bacterial Identification and Susceptibility Testing
  • Streptococcal Infections and Treatments
  • Antibiotic Use and Resistance
  • Infection Control in Healthcare
  • Hepatitis Viruses Studies and Epidemiology
  • Orthopedic Infections and Treatments
  • COVID-19 epidemiological studies
  • Vibrio bacteria research studies
  • Legionella and Acanthamoeba research
  • Viral gastroenteritis research and epidemiology
  • Respiratory viral infections research
  • Health, Medicine and Society
  • Vaccine Coverage and Hesitancy

Centre International de Recherche en Infectiologie
2020-2024

Inserm
1996-2024

École Normale Supérieure de Lyon
2020-2024

Centre National de la Recherche Scientifique
2020-2024

Université Claude Bernard Lyon 1
2015-2024

Centre Hospitalier Universitaire de Saint-Étienne
2015-2024

Université Jean Monnet
2010-2024

Hôpital Nord
2004-2023

Université de Lyon
2010-2020

Pathophysiology, Diagnosis and Treatment of Bone Diseases
2016

THE association of hepatic cirrhosis with cyanosis and finger clubbing1 2 3 4 arterial oxygen desaturation4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 has been recognized for many years, the possible basis investigated. Abnormalities in dissociation curve cirrhotic patients have reported6 but not confirmed.11 , More recently, Caldwell, Fritts Cournand20 again called attention to abnormal tension-saturation relations concluded that contribution these toward unsaturation was probably small....

10.1056/nejm196602102740601 article EN New England Journal of Medicine 1966-02-10

Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms of protection against reinfection and, thus, for public health policy and vaccine development COVID-19. In this study, using either live particles or retroviruses pseudotyped with S viral surface protein (Spike), we studied neutralizing antibody (nAb) response serum samples from a cohort 140 qPCR-confirmed infections, including patients mild symptoms also more severe forms, those that required intensive...

10.1038/s41423-020-00588-2 article EN cc-by Cellular and Molecular Immunology 2021-01-06
Kostas Danis Olivier Épaulard Thomas Bénet Alexandre Gaymard Séphora Campoy and 87 more Élisabeth Botelho-Nevers Maude Bouscambert‐Duchamp Guillaume Spaccaferri Florence Ader Alexandra Mailles Zoubida Boudalaa V. Tolsma Julien Berra Sophie Vaux E. Forestier Caroline Landelle Erica Fougère A. Thabuis P. Berthelot Raphaël Veil D Lévy-Brühl Christian Chidiac Bruno Lina B. Coignard C. Saura Élise Brottet Delphine Casamatta Yves Gallien Scarlett George Delphine Viriot Fatima Aït El Belghiti Sibylle Bernard-Stoecklin Jean‐Claude Desenclos Coralie Giese Didier Ghislain Mathieu Gounon N. Grangeret Cécile Marie Bruno Morel Muriel Deher Anne-Sophie Ronnaux Baron Geneviève Courbis Nathalie Ragozin Monika Wolska Eric Serange Delphine Mercatello Soraya Aiouaz Martine Valette Émilie Frobert Laurence Josset Vanessa Escuret Florence Morfin Geneviève Billaud Myriam Blanc Julie Arata-Bardet Marie Froidure Marion Le Maréchal Patricia Pavèse Isabelle Pierre Agathe Becker Pierre Chauvelot Anne Conrad Tristan Ferry Patrick Miailhes Thomas Perpoint Cécile Pouderoux Sandrine Roux Florent Valour Marie-France Lutz Anne Pouvaret Virginie Vitrat Mylène Maillet C. Janssen E. Piet Alexie Bosch A. Destrem Margaux Isnard Thibault Challan-Belval C. Wackenheim Alice Couturier Gael Gheno T Roupioz Nicolas Lucet Stéphane Ayouni Mireille Vincent Servicio de Epidemiología Dirección General de Salud Pública del Gover Balear Virginie Masserey Spicher C Bourquin Jeanine Stoll P. Chaud Anne-Laure Mounayar

Abstract Background On 7 February 2020, French Health authorities were informed of a confirmed case severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an Englishman infected Singapore who had recently stayed chalet the Alps. We conducted investigation to identify secondary cases and interrupt transmission. Methods defined as person linked with positive reverse-transcription polymerase chain reaction sample for SARS-CoV-2. Results The index 4 days 10 English tourists family 5...

10.1093/cid/ciaa424 article EN cc-by-nc-nd Clinical Infectious Diseases 2020-04-09

10.1152/ajplegacy.1970.219.3.809 article EN American Journal of Physiology-Legacy Content 1970-09-01

Previous studies have suggested an association between cytomegalovirus (CMV) infection and steroid-refractory inflammatory bowel disease. In this study, the use of CMV DNA load during acute flare-ups ulcerative colitis (UC) to predict resistance immunosuppressive therapy was evaluated in intestinal tissue. Forty-two consecutive patients (sex ratio M/F: 0.9, mean age: 43.6 years) hospitalized for moderate severe UC treated with IV steroids were included prospectively. A colonoscopy performed...

10.1038/ajg.2011.202 article EN The American Journal of Gastroenterology 2011-07-26

10.1152/ajplegacy.1970.219.2.416 article EN American Journal of Physiology-Legacy Content 1970-08-01

Liver function and serum concentrations of rifampicin, a highly cholephilic antibiotic, have been studied after ingestion single dose 600 mg rifampicin in 12 patients, six them having normal liver cirrhotic, during treatment with per day for 17 days eight four cirrhotic. Rifampicin produced competition the elimination bilirubin bromsulphalein by liver. This competition, which seemed to involve mainly uptake cell, was always rapidly reversible when discontinued. It makes it impossible,...

10.1136/gut.13.5.366 article EN Gut 1972-05-01

Legionella viability was monitored during heat shock treatment at 70 degrees C by a flow cytometric assay (FCA). After 30 min of treatment, for 6 the 12 strains tested, FCA still detected 10 to 25% cells that were viable but nonculturable (VBNC). These VBNC able produce ATP and be resuscitated after culture on amoebae.

10.1128/aem.01364-08 article EN Applied and Environmental Microbiology 2008-10-11

In this study, we systematically investigated the resistance mechanisms to beta-lactams, aminoglycosides, and fluoroquinolones of 120 bacteremic strains Pseudomonas aeruginosa. Pulsed-field gel electrophoresis genotyping showed that 97 these were represented by a single isolate, 10 2 1 3 clonally related isolates, respectively. Seventy-five percent (90 out 120) P. aeruginosa displayed significant one or more tested antimicrobials (up 11 for strain). These found harbor great diversity 7 in...

10.1128/aac.00503-07 article EN Antimicrobial Agents and Chemotherapy 2007-08-07

Legionella spp. are frequently isolated in hospital water systems. Heat shock (30 min at 70°C) is recommended by the World Health Organization to control its multiplication. The aim of study was evaluate retrospectively efficacy heat treatments using a flow cytometry assay (FCA) able identify viable but nonculturable (VBNC) cells. included strains (L. pneumophila [3 clusters] and L. anisa [1 cluster]) from four hot circuits different buildings Saint-Etienne, France, during 20-year...

10.1128/aem.02225-10 article EN Applied and Environmental Microbiology 2010-12-24
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