- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Resistance in Bacteria
- Bacterial biofilms and quorum sensing
- Drug-Induced Hepatotoxicity and Protection
- Healthcare Systems and Practices
- Drug Transport and Resistance Mechanisms
- Nosocomial Infections in ICU
- Neonatal Health and Biochemistry
- Metabolism and Genetic Disorders
- Bacterial Identification and Susceptibility Testing
- Streptococcal Infections and Treatments
- Antibiotic Use and Resistance
- Infection Control in Healthcare
- Hepatitis Viruses Studies and Epidemiology
- Orthopedic Infections and Treatments
- COVID-19 epidemiological studies
- Vibrio bacteria research studies
- Legionella and Acanthamoeba research
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Health, Medicine and Society
- Vaccine Coverage and Hesitancy
Centre International de Recherche en Infectiologie
2020-2024
Inserm
1996-2024
École Normale Supérieure de Lyon
2020-2024
Centre National de la Recherche Scientifique
2020-2024
Université Claude Bernard Lyon 1
2015-2024
Centre Hospitalier Universitaire de Saint-Étienne
2015-2024
Université Jean Monnet
2010-2024
Hôpital Nord
2004-2023
Université de Lyon
2010-2020
Pathophysiology, Diagnosis and Treatment of Bone Diseases
2016
THE association of hepatic cirrhosis with cyanosis and finger clubbing1 2 3 4 arterial oxygen desaturation4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 has been recognized for many years, the possible basis investigated. Abnormalities in dissociation curve cirrhotic patients have reported6 but not confirmed.11 , More recently, Caldwell, Fritts Cournand20 again called attention to abnormal tension-saturation relations concluded that contribution these toward unsaturation was probably small....
Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms of protection against reinfection and, thus, for public health policy and vaccine development COVID-19. In this study, using either live particles or retroviruses pseudotyped with S viral surface protein (Spike), we studied neutralizing antibody (nAb) response serum samples from a cohort 140 qPCR-confirmed infections, including patients mild symptoms also more severe forms, those that required intensive...
Abstract Background On 7 February 2020, French Health authorities were informed of a confirmed case severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an Englishman infected Singapore who had recently stayed chalet the Alps. We conducted investigation to identify secondary cases and interrupt transmission. Methods defined as person linked with positive reverse-transcription polymerase chain reaction sample for SARS-CoV-2. Results The index 4 days 10 English tourists family 5...
Previous studies have suggested an association between cytomegalovirus (CMV) infection and steroid-refractory inflammatory bowel disease. In this study, the use of CMV DNA load during acute flare-ups ulcerative colitis (UC) to predict resistance immunosuppressive therapy was evaluated in intestinal tissue. Forty-two consecutive patients (sex ratio M/F: 0.9, mean age: 43.6 years) hospitalized for moderate severe UC treated with IV steroids were included prospectively. A colonoscopy performed...
Liver function and serum concentrations of rifampicin, a highly cholephilic antibiotic, have been studied after ingestion single dose 600 mg rifampicin in 12 patients, six them having normal liver cirrhotic, during treatment with per day for 17 days eight four cirrhotic. Rifampicin produced competition the elimination bilirubin bromsulphalein by liver. This competition, which seemed to involve mainly uptake cell, was always rapidly reversible when discontinued. It makes it impossible,...
Legionella viability was monitored during heat shock treatment at 70 degrees C by a flow cytometric assay (FCA). After 30 min of treatment, for 6 the 12 strains tested, FCA still detected 10 to 25% cells that were viable but nonculturable (VBNC). These VBNC able produce ATP and be resuscitated after culture on amoebae.
In this study, we systematically investigated the resistance mechanisms to beta-lactams, aminoglycosides, and fluoroquinolones of 120 bacteremic strains Pseudomonas aeruginosa. Pulsed-field gel electrophoresis genotyping showed that 97 these were represented by a single isolate, 10 2 1 3 clonally related isolates, respectively. Seventy-five percent (90 out 120) P. aeruginosa displayed significant one or more tested antimicrobials (up 11 for strain). These found harbor great diversity 7 in...
Legionella spp. are frequently isolated in hospital water systems. Heat shock (30 min at 70°C) is recommended by the World Health Organization to control its multiplication. The aim of study was evaluate retrospectively efficacy heat treatments using a flow cytometry assay (FCA) able identify viable but nonculturable (VBNC) cells. included strains (L. pneumophila [3 clusters] and L. anisa [1 cluster]) from four hot circuits different buildings Saint-Etienne, France, during 20-year...