Christian Chidiac
A5020778242- HIV/AIDS Research and Interventions
- Pneumocystis jirovecii pneumonia detection and treatment
- Healthcare Systems and Practices
- HIV Research and Treatment
- HIV, Drug Use, Sexual Risk
- HIV/AIDS drug development and treatment
- COVID-19 and Mental Health
- Pneumonia and Respiratory Infections
- Tuberculosis Research and Epidemiology
- Health, Medicine and Society
- Antibiotics Pharmacokinetics and Efficacy
- Hepatitis C virus research
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Use and Resistance
- Influenza Virus Research Studies
- Antimicrobial Resistance in Staphylococcus
- Mycobacterium research and diagnosis
- Streptococcal Infections and Treatments
- Bacterial Infections and Vaccines
- Infectious Diseases and Tuberculosis
- Viral Infections and Outbreaks Research
- Orthopedic Infections and Treatments
- COVID-19 epidemiological studies
- Respiratory viral infections research
- Vaccine Coverage and Hesitancy
Université Claude Bernard Lyon 1
2015-2024
Hospices Civils de Lyon
2015-2024
Inserm
2012-2024
Centre International de Recherche en Infectiologie
2013-2024
École Normale Supérieure de Lyon
2013-2024
Centre National de la Recherche Scientifique
2013-2024
Hôpital de la Croix-Rousse
2014-2023
Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes
2023
Institut de Recherche pour le Développement
2022
Economic & Social Sciences, Health Systems & Medical Informatics
2022
Antiretroviral preexposure prophylaxis has been shown to reduce the risk of human immunodeficiency virus type 1 (HIV-1) infection in some studies, but conflicting results have reported among probably due challenges adherence a daily regimen.We conducted double-blind, randomized trial antiretroviral therapy for HIV-1 men who unprotected anal sex with men. Participants were randomly assigned take combination tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC) or placebo before after...
Abstract Background On 7 February 2020, French Health authorities were informed of a confirmed case severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an Englishman infected Singapore who had recently stayed chalet the Alps. We conducted investigation to identify secondary cases and interrupt transmission. Methods defined as person linked with positive reverse-transcription polymerase chain reaction sample for SARS-CoV-2. Results The index 4 days 10 English tourists family 5...
Significance A detailed characterization of viral load kinetics and its association with disease evolution is key to understand the virus pathogenesis, identify high-risk patients, design better treatment strategies. We here analyze mortality virological information collected in 655 hospitalized including 284 longitudinal measurements, we build a mathematical model dynamics survival. predict that peak occurs 1 d before symptom onset, on average, decline after slower older patients. Viral...
There have been many epidemiological studies of chickenpox but only a few herpes zoster. We report data from an observational study, conducted in France during 1-year period, 9038 patients who presented with acute zoster (n = 8103) or postherpetic neuralgia (PHN; n 935) at the office practices 4635 general practitioners dermatologists. The incidence was found to be similar that literature: 1.4 4.8 cases per 1000 population year. patient profiles and clinical patterns were delineated, as well...
AimsThe aim of this study was to evaluate the effect valve surgery (VS) in infective endocarditis (IE) on 5-year mortality and whether conflicting results reported by previous studies could be due differences their methodological approaches.
<h3>Importance</h3> Infective endocarditis (IE) is a rare disease with poor prognosis. When IE suspected, skin examination mandatory to look for portal of entry and classic lesions help diagnose manage the condition. <h3>Objectives</h3> To describe prevalence factors associated dermatological manifestations in patients definite IE. <h3>Design</h3> Observational, prospective, population-based epidemiological study between January 1 December 31, 2008. Subsequently, collected data were...
The double-blind phase of the randomized ANRS IPERGAY trial, evaluating sexual activity-based oral HIV pre-exposure prophylaxis (PrEP), was conducted among high-risk men who have sex with (MSM). Results showed an 86% (95% CI: 40–98) relative reduction in incidence participants tenofovir disoproxil fumarate–emtricitabine vs. placebo. present pooled analysis aimed to analyze (i) participants' adherence prescribed treatment and/or condom use during intercourse and (ii) behavior study. Four...
Background Aspecific scoring systems are used to predict the risk of death postsurgery in patients with infective endocarditis ( IE ). The purpose present study was both analyze factors for in‐hospital death, which complicates surgery , and create a mortality score based on results this analysis. Methods Results Outcomes 361 consecutive (mean age, 59.1±15.4 years) who had undergone 8 European centers cardiac were recorded prospectively, factor analysis (multivariable logistic regression)...
As HIV-infected adults on successful antiretroviral therapy (ART) are expected to have close normal lifespans, they will increasingly develop age-related comorbidities. The objective of this cross-sectional study was compare in the French Dat'AIDS cohort, HIV geriatric population, aged 75 years and over, elderly one, from 50 74 years. Dec 2015, 16,436 subjects (43.8% cohort) were (elderly group) 572 (1.5%) over (geriatric group). Durations infection ART slightly but significantly different,...
Sexually transmitted acute hepatitis C virus (HCV) infections (AHIs) have been mainly described in human immunodeficiency (HIV)-infected men who sex with (MSM). Cases HIV-negative MSM are scarce. We describe the epidemic of AHI HIV-infected and Lyon, France.All cases diagnosed Lyon University Hospital from 2014 to 2017 were included. incidence was determined preexposure prophylaxis (PrEP)-using MSM. Transmission clusters identified by construction phylogenetic trees based on HCV NS5B...
To describe characteristics of infective endocarditis (IE) in pacemaker (PM) recipients, including the annual incidence and exact localization IE on PM leads, cardiac valves, or both, we prospectively analyzed 45 recipients from a group 559 patients with definite who responded to population-based survey conducted France 1999. Thirty-three had PM-lead (group I), 12 valvular without evidence involvement II). The structure was involved almost two-thirds cases among recipients. Of 28 (62%) IE,...
HCV incidence still appears on the rise in HIV-infected MSM France. We assessed of infection HIV-positive and preexposure prophylaxis (PrEP)-using MSM.
Mycoplasma genitalium (MG) is an emerging pathogen among men who have sex with (MSM) raising rates of antibiotic resistance. This study assessed the prevalence and incidence MG infection in MSM enrolled open-label phase ANRS IPERGAY trial on-demand tenofovir disoproxil fumarate/emtricitabine for human immunodeficiency virus prevention impact doxycycline post-exposure prophylaxis (PEP).210 subjects were tested at baseline 6 months by real-time PCR assays detection urine samples oropharyngeal...
High rates of sexually transmitted infections (STIs) have been reported among pre-exposure prophylaxis (PrEP) users. We wished to assess the incidence and risk factors for recurrent STIs.The ANRS IPERGAY trial was a prospective study investigating PrEP MSM transgender women in outpatient clinics France Canada. In all, 429 participants were enrolled, offered up 4 years screened bacterial STIs (syphilis, chlamydia gonorrhea) at baseline every 6 months.STIs calculated yearly. Cox proportional...