- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Knee injuries and reconstruction techniques
- Lower Extremity Biomechanics and Pathologies
- Sports injuries and prevention
- Shoulder Injury and Treatment
- Hip disorders and treatments
- Antimicrobial Resistance in Staphylococcus
- Bacteriophages and microbial interactions
- Orthopedic Surgery and Rehabilitation
- Tendon Structure and Treatment
- Infectious Diseases and Tuberculosis
- Hip and Femur Fractures
- Foot and Ankle Surgery
- Surgical site infection prevention
- Osteoarthritis Treatment and Mechanisms
- Infective Endocarditis Diagnosis and Management
- Musculoskeletal Disorders and Rehabilitation
- Hepatitis B Virus Studies
- Antibiotics Pharmacokinetics and Efficacy
- Bacillus and Francisella bacterial research
- Antimicrobial agents and applications
- Antibiotic Resistance in Bacteria
- Pelvic and Acetabular Injuries
Hospices Civils de Lyon
2016-2025
Université Claude Bernard Lyon 1
2016-2025
Hôpital de la Croix-Rousse
2016-2025
Université Gustave Eiffel
2021-2025
Institut des Hautes Études Scientifiques
2016-2025
Servier (France)
2016-2025
Laboratoire de Biomécanique et Mécanique des Chocs
2016-2024
Lyon Genou Centre Albert Trillat
2016-2024
Sydney Orthopaedic Research Institute
2023
Hornsby Ku-ring-gai Hospital
2023
Traditionally in total knee arthroplasty (TKA), a post-operative neutral alignment was the gold standard. This principle has been contested as functional outcomes were found to be inconsistent. Analysis of limb non-osteoarthritic population reveals variations from and consideration personalized or patient-specific TKA is challenging previous concepts. The aim this review clarify current alignments report their results. Current approaches reported are: kinematic, inverse restricted...
Abstract Purpose Functional alignment (FA) in total knee arthroplasty (TKA) prioritizes soft tissue balancing and anatomical restoration without systematic correction to neutral alignment. Most studies have focused on varus deformity, with little evidence available about FA valgus deformity. The hypothesis of the present study was that robotic‐assisted TKA for deformity would demonstrate coronal yield satisfactory short‐term outcomes. Methods This retrospective included 58 patients...
Background : Functional knee positioning (FKP) represents an innovative personalized approach for total arthroplasty (TKA) that reconstructs a three-dimensional alignment based on the optimal balance of soft tissue and bony structures, but it has mostly been described varus deformity. Surgical technique Valgus deformities present specific challenges due to altered bone remodeling imbalances. Using robotic assistance, FKP enables precise intraoperative assessment correction compartmental...
Local injection of a bacteriophages mix during debridement, antibiotics and implant retention ("DAIR") was performed to treat relapsing Staphylococcus aureus chronic prosthetic joint infection (PJI). This salvage treatment safe associated with clinical success. Scientific evaluation the potential benefit as antibiofilm in PJI is now feasible required.
Objectives: To report the management of 3 consecutive patients with relapsing S. aureus prosthetic knee infection (PKI) for whom explantation was not feasible who received a phage therapy during 'Debridement Antibiotics and Implant retention' (DAIR) procedure followed by suppressive antimicrobial therapy. Methods: Each case discussed individually in our reference center French National Agency (ANSM). The lytic activity phages targeting aureus, that produced controlled reproducible process,...
Background: Arthroscopic anterior cruciate ligament (ACL) reconstruction (ACLR) with a bone–patellar tendon–bone graft (BTB) is reliable surgical option for the control of knee laxity after ACL injury. The addition lateral extra-articular tenodesis (LET) may improve rotation and short-term survival in high-risk patients. Purpose: aims this study were to compare long-term patient-reported outcomes, survival, risk osteoarthritis between ACLR without LET. Study Design: Randomized controlled...
Functional alignment (FA) is a novel philosophy to deliver total knee arthroplasty (TKA) that respects individual bony and soft tissue phenotypes within defined limitations. The purpose of this paper describe the rationale technique FA in valgus morphotype with use an image-based robotic-platform. For phenotype principles are personalized pre-operative planning, reconstitution native coronal without residual varus or more than 3°, restoration dynamic sagittal 5° neutral, implant sizing match...
Robotic-assisted total knee arthroplasty (TKA) and new alignment principles are transforming traditional implant positioning, not only in the coronal plane but also sagittal axial planes. The impact of differences between a patient's native tibial slope (TS) distal femoral flexion (DFF) compared to final positioning remains unclear. This study aims evaluate whether variations TS (ΔTS) DFF (ΔDFF) play role clinical outcomes survival. retrospective analysed patients who underwent...
Recurrent patellar dislocation is a disabling condition, which can lead to articular cartilage injuries, osteochondral fractures, recurrent instability, pain, decreased activity and patellofemoral osteoarthritis. Trochlear dysplasia represents an important component of dislocation. Imaging provides objective basis for the morphological abnormalities thus allows determination surgical strategy according concept ‘à la carte’ surgery. The main techniques trochleoplasty are sulcus deepening...
Infection is the most dramatic complication in patients with knee megaprosthesis. Its management more complex comparison primary arthroplasty, a high risk of relapse. Lytic bacteriophages are considered to have potential patient prosthetic joint infection, as it has been demonstrated that they synergistic anti-biofilm activity antibiotics. The Defensive Antibacterial Coating (DAC®) hydrogel available market designed prevent adherence bacteria on and ability transport release anti-bacterial...