- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Ear and Head Tumors
- Tracheal and airway disorders
- Oral and Maxillofacial Pathology
- Sinusitis and nasal conditions
- Reconstructive Surgery and Microvascular Techniques
- Voice and Speech Disorders
- Airway Management and Intubation Techniques
- Lung Cancer Treatments and Mutations
- Cancer Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Colorectal and Anal Carcinomas
- Dysphagia Assessment and Management
- Head and Neck Anomalies
- Facial Nerve Paralysis Treatment and Research
- Tumors and Oncological Cases
- Esophageal Cancer Research and Treatment
- Cancer Immunotherapy and Biomarkers
- Reconstructive Facial Surgery Techniques
- Otolaryngology and Infectious Diseases
- Pituitary Gland Disorders and Treatments
- Oral Health Pathology and Treatment
- Lung Cancer Diagnosis and Treatment
Université de Toulouse
2012-2025
Hôpital Larrey
2016-2025
Université Toulouse III - Paul Sabatier
2010-2025
Institut universitaire du cancer de Toulouse Oncopole
2014-2024
Centre Hospitalier Universitaire de Toulouse
2015-2024
Hôpital Rangueil
2010-2024
Laboratoire de Physique des 2 Infinis Irène Joliot-Curie
2024
Centre Hospitalier Universitaire de Montpellier
2024
Institut Claudius Regaud
2010-2023
Biotherapy of Genetic Diseases, Inflammatory Disorders and Cancers
2020-2021
Sentinel node (SN) biopsy is accurate in operable oral and oropharyngeal cT1-T2N0 cancer (OC), but, to our knowledge, the oncologic equivalence of SN neck lymph dissection (ND; standard treatment) has never been evaluated.In this phase III multicenter trial, 307 patients with OC were randomly assigned (1) ND arm or (2) (experimental arm: alone if negative, followed by positive, during primary tumor surgery). The outcome was recurrence-free survival (RFS) at 2 years. Secondary outcomes 5-year...
Objective: To report patterns of failure according to treatment modality, with an emphasis on the role postoperative radiotherapy in patients localized head and neck mucosal melanoma (HNMM) treated during a 28-year period multi-institutional setting.Design: Retrospective review.Setting: French medical institutions.Patients: A total 160 nonmetastatic HNMM from 1980 through 2008.Interventions: Treatment modality consisted surgery alone (hereinafter, S group) (n=82 patients) or SRT...
Tumor antigen–specific CD4 T cells accumulate at tumor sites, evoking their involvement in antitumor effector functions situ. Contrary to CD8 cytotoxic lymphocyte exhaustion, that of remains poorly appreciated. Here, using phenotypic, transcriptomic, and functional approaches, we characterized cell exhaustion patients with head neck, cervical, ovarian cancer. We identified a tumor-infiltrating (TIL) population, defined by high PD-1 CD39 expression, which contained proportions...
Objective The coronavirus disease 2019 (COVID‐19) pandemic has led to a global surge in critically ill patients requiring invasive mechanical ventilation, some of whom may benefit from tracheostomy. Decisions on if, when, and how perform tracheostomy with COVID‐19 have major implications for patients, clinicians, hospitals. We investigated the protocols practices that institutions around world put into place response pandemic. Data Sources Protocols severe acute respiratory syndrome 2...
Objective To assess the initial experience for transoral robotic surgery (TORS), as observed in French TORS group. Study Design A multi‐institutional prospective cohort study. Setting Seven tertiary referral centers. Subjects and Methods One hundred thirty consecutive patients who were scheduled a between October 2008 March 2011 included. The operative times, conversion rates, morbidity, alternatives described. serious adverse effects encountered analyzed, recommendations avoiding them are...
Abstract Background Transoral, minimally invasive, organ preservation surgeries are increasingly used to treat laryngopharyngeal carcinomas avoid the toxicity associated with combined chemoradiotherapy (CRT) regimens. This study investigated efficiency, safety, and functional outcomes of using transoral robotic surgery (TORS) perform supraglottic laryngectomy (SGL). Methods was a multicenter case series planned data collection from 2009 2012 for patients squamous cell (SCCs) who underwent an...
To describe the evolution of incidence oral cavity cancers (OCC) among elderly patients in France between 1990 and 2018 to compare it other sharing same main risk factors.The mainland from was estimated data observed every cancer registry Francim network. Incidence modeled by a 2-dimensional penalized spline age year diagnosis, associated with random effect corresponding registry. The population divided into two groups: 70-79 years old ≥80 old.There 72% increase number OCC cases women over...