- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Salivary Gland Tumors Diagnosis and Treatment
- Dysphagia Assessment and Management
- Ear and Head Tumors
- Voice and Speech Disorders
- Ear Surgery and Otitis Media
- Cancer Diagnosis and Treatment
- Facial Nerve Paralysis Treatment and Research
- Head and Neck Anomalies
- Oral and Maxillofacial Pathology
- Esophageal and GI Pathology
- Olfactory and Sensory Function Studies
- Otolaryngology and Infectious Diseases
- Nasal Surgery and Airway Studies
- Tumors and Oncological Cases
- Sinusitis and nasal conditions
- Reconstructive Surgery and Microvascular Techniques
- Management of metastatic bone disease
- Lung Cancer Treatments and Mutations
- Vascular Malformations and Hemangiomas
- Vascular Anomalies and Treatments
- Bone Tumor Diagnosis and Treatments
- Obstructive Sleep Apnea Research
Centre Hospitalier Universitaire de Tours
2015-2024
Hôpital Bretonneau
2014-2024
Université de Tours
2013-2024
Hôpital Tenon
2022
Assistance Publique – Hôpitaux de Paris
2022
Sorbonne Université
2022
Université de Bordeaux
2022
Thion Medical (France)
2015-2021
Aix-Marseille Université
2020
Hôpital de la Conception
2020
Objective To assess the initial experience for transoral robotic surgery (TORS), as observed in French TORS group. Study Design A multi‐institutional prospective cohort study. Setting Seven tertiary referral centers. Subjects and Methods One hundred thirty consecutive patients who were scheduled a between October 2008 March 2011 included. The operative times, conversion rates, morbidity, alternatives described. serious adverse effects encountered analyzed, recommendations avoiding them are...
Abstract Background Transoral, minimally invasive, organ preservation surgeries are increasingly used to treat laryngopharyngeal carcinomas avoid the toxicity associated with combined chemoradiotherapy (CRT) regimens. This study investigated efficiency, safety, and functional outcomes of using transoral robotic surgery (TORS) perform supraglottic laryngectomy (SGL). Methods was a multicenter case series planned data collection from 2009 2012 for patients squamous cell (SCCs) who underwent an...
Persistent olfactory dysfunction is a significant complication of SARS-CoV-2 infection. Olfactory training involving aromatic oils has been recommended to improve recovery, but quantitative data are missing.We aimed quantify the benefit and visual stimulation assisted by dedicated web application for patients who experienced ≥1 month.We performed an observational, real-life, data-based study on cohort at least 1 month persistent between January 30 March 26, 2021. An analysis was after mean...
The purpose of our work was to compare a group patients undergoing transoral robotic surgery (TORS group) for squamous cell carcinoma the upper aerodigestive tract and matched conventional (conventional same indication.In this retrospective single-center study, 26 were included in each group.There significantly fewer tracheotomies TORS (p < .001). mean durations feeding by nasogastric tube hospitalization shorter = There no significant difference disease-free survival at 3 years .76). Mean...
To determine whether treatment of acute mastoiditis in children using antibiotics combined with retroauricular puncture and grommet insertion is effective compared "standard management" mastoidectomy.Retrospective study.Tertiary pediatric center.We identified 50 patients younger than 14 years (mean age, 32 months). Individuals subacute cholesteatoma were excluded from this study. All the had received antibiotic drug treatment. Before 2002, a subperiosteal abscess (SA) was managed by...
Abstract Background Transoral robotic surgery (TORS) is an option to treat supraglottic squamous cell carcinomas (SCCs). We studied the oncologic outcomes after TORS for laryngectomy (SGL). Methods conducted a multicenter observational study of SGL using patients with SCC at least 2 years follow‐up. Results One hundred twenty‐two were included in our study. Mean follow‐up was 42.8 months. Local control 94.3% and 90.2% 5 years. Overall survival disease‐free 86.9% 95.1% years, 78.7%...
Objectives: Squamous cell carcinoma (SCC) in young people is rare and the literature confusing. This study was carried out to assess demographics, clinical features, treatment outcome a cohort of patients aged 35 years or less with SCC oral tongue (SCCOT). Patients methods: multicenter retrospective study. Fifty-two treated between 1990 2000 were identified. Descriptive statistics analyzed demographic tumor variables. Results: The WHO performance status excellent for all patients....
Epidermal growth factor receptor (EGFR) overexpression is associated with poor prognosis in head and neck squamous cell carcinoma (HNSCC). Despite intensive biomarker studies, a consensual method for assessing EGFR protein expression still lacking. Here we set out to compare three detection methods tumor specimens from HNSCC patients.Tumors were prospectively excised series of 79 high-risk patients enrolled GORTEC-sponsored clinical trial. was determined using ligand-binding assay on...
Intermediate/high-risk operated patients with head and neck cancer may benefit from the addition of EGF receptor (EGFR) inhibitor gefitinib to chemoradiation. This study was designed assess improved outcomes identify predictive biomarkers.Patients provided informed consent for tumor biomarker analyses and, when eligible, were further enrolled in therapeutic CARISSA multicenter randomized phase II trial postoperative irradiation cisplatin + (GORTEC 2004-02-NCT00169221).Seventy-nine included...