A5062120751- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Ear and Head Tumors
- Head and Neck Surgical Oncology
- Tracheal and airway disorders
- Oral and Maxillofacial Pathology
- Voice and Speech Disorders
- Adrenal and Paraganglionic Tumors
- Dysphagia Assessment and Management
- Pituitary Gland Disorders and Treatments
- Cancer Diagnosis and Treatment
- Head and Neck Anomalies
- Cancer, Hypoxia, and Metabolism
- Reconstructive Surgery and Microvascular Techniques
- Tumors and Oncological Cases
- COVID-19 and healthcare impacts
- Thyroid Cancer Diagnosis and Treatment
- Airway Management and Intubation Techniques
- Sinusitis and nasal conditions
- Colorectal and Anal Carcinomas
- Delphi Technique in Research
- Radiomics and Machine Learning in Medical Imaging
- Vascular Malformations and Hemangiomas
- Neurofibromatosis and Schwannoma Cases
- Meningioma and schwannoma management
Aix-Marseille Université
2016-2025
Hôpital de la Conception
2015-2024
Assistance Publique Hôpitaux de Marseille
2014-2024
Laboratoire Parole et Langage
2012-2024
Centre National de la Recherche Scientifique
2014-2024
Université Claude Bernard Lyon 1
2024
Hospices Civils de Lyon
2024
Hôpital de la Timone
2011-2023
Biotherapy of Genetic Diseases, Inflammatory Disorders and Cancers
2013-2021
International Society of Nephrology
2020
The clinical presentation of European patients with mild-to-moderate COVID-19 infection is still unknown.
Sentinel node (SN) biopsy is accurate in operable oral and oropharyngeal cT1-T2N0 cancer (OC), but, to our knowledge, the oncologic equivalence of SN neck lymph dissection (ND; standard treatment) has never been evaluated.In this phase III multicenter trial, 307 patients with OC were randomly assigned (1) ND arm or (2) (experimental arm: alone if negative, followed by positive, during primary tumor surgery). The outcome was recurrence-free survival (RFS) at 2 years. Secondary outcomes 5-year...
Harnessing innate immunity is emerging as a promising therapeutic approach in cancer. We report here the design of tetraspecific molecules engaging natural killer (NK) cell-activating receptors NKp46 and CD16a, β-chain interleukin-2 receptor (IL-2R), tumor-associated antigen (TAA). In vitro, these antibody-based cell engager therapeutics (ANKETs) induce preferential activation proliferation NK cells, binding to targeted TAA triggers cytotoxicity cytokine chemokine production. vivo, ANKETs...
Our objective was to evaluate (18)F-FDG PET uptake in patients with nonmetastatic and metastatic chromaffin-derived tumors.Twenty-eight consecutive unrelated chromaffin tumors, including 9 genetically determined disease, were studied. A combination of preoperative imaging work-up, surgical findings, pathologic analyses used classify the into 2 groups: those disease (presumed benign, n = 18) tumors (n 10). performed all cases. Visual quantitative individually graded for each tumor. Somatic...
<h2>Abstract</h2><h3>Purpose</h3> This phase I study assessed the safety of first-in-class radioenhancer nanoparticles, NBTXR3, in elderly or frail patients with locally advanced head and neck squamous cell carcinoma (HNSCC), ineligible for chemoradiation. <h3>Methods</h3> Patients stage III IVA (American Joint Committee on Cancer (AJCC) guidelines, 7th edition, 2010) HNSCC oral cavity oropharynx, aged ≥70 ≥65 years to receive cisplatin, amenable radiotherapy (RT) curative intent, received...
The purpose of this study was to assess the prognostic value 3 staging systems found in literature for sinonasal mucosal melanomas tumors: Ballantyne system modified by Prasad (Ballantyne/Prasad system), American Joint Committee on Cancer (AJCC) TNM classification (mmTNM), and 2009 AJCC carcinomas nasal cavity sinuses (carTNM).A retrospective 35 patients treated between 1995 2010 conducted study. Each patient retrospectively staged using Ballantyne/Prasad system, mmTNM, carTNM.There were 20...
Administration of first-in-class anti-EGFR monoclonal antibody cetuximab is contingent upon extensive pharmacogenomic testing. However in addition to tumor genomics, drug exposure levels could play a critical, yet largely underestimated role, because several reports have demonstrated that pharmacokinetic parameters, particular clearance values, were associated with survival patients. Here, we developed an original bioanalytical method based the use LC-MS/MS technology and simplified sample...