- Head and Neck Cancer Studies
- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Ear and Head Tumors
- Ear Surgery and Otitis Media
- Salivary Gland Tumors Diagnosis and Treatment
- Nutrition and Health in Aging
- Tracheal and airway disorders
- Hearing Loss and Rehabilitation
- Allergic Rhinitis and Sensitization
- Esophageal and GI Pathology
- Hearing, Cochlea, Tinnitus, Genetics
- Meningioma and schwannoma management
- Infectious Diseases and Mycology
- Nasal Surgery and Airway Studies
- Cutaneous Melanoma Detection and Management
- Otolaryngology and Infectious Diseases
- Oral and Maxillofacial Pathology
- Advanced Radiotherapy Techniques
- Vestibular and auditory disorders
- Voice and Speech Disorders
- Lung Cancer Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Oral health in cancer treatment
- Facial Nerve Paralysis Treatment and Research
Université Clermont Auvergne
2014-2025
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2021-2025
Unité de Nutrition Humaine
2021-2025
Centre de Recherche en Nutrition Humaine d'Auvergne
2021-2025
Centre Hospitalier Universitaire de Clermont-Ferrand
2014-2024
Inserm
2013-2016
Université de Rouen Normandie
2016
Centre Hospitalier Universitaire de Rouen
2016
Clermont Université
2013-2014
Bevacizumab-a humanized monoclonal antibody-has been widely used to treat patients with hereditary hemorrhagic telangiectasia (HHT), but no randomized trial has yet conducted.This study is a double-blind multicenter phase 2 1:1 active-treatment-to-placebo ratio. We included over the age of 18 confirmed diagnosis and need for at least four red blood cell (RBC) units transfused in 3 months before enrollment. Bevacizumab was administered dose 5 mg/kg every 14 days total six injections. The...
Objective Investigation of long-term satisfaction and correlation with audiometric measurements after osseointegrated bone-conduction device (OBCD) surgery for patients single-sided deafness (SSD). Patients Thirty-six implanted an OBCD SSD. Study Design Retrospective review in a university medical center. Intervention Rehabilitative. The were test worn on headband during 15 days daily use. if the gave us satisfaction. Main Outcome Measures A series tests, including speech perception noise,...
Objective To assess the value of several diagnostic methods nutritional status during initial management a head and neck cancer. Study Design Single‐center prospective study. Setting Tertiary referral center. Subjects Methods Ninety patients with cancer participated in Assessment their was made anthropometric, biological, body, muscle measurements (the last by computed tomography: L3 mass index [L3MMI]). performance (functional reflection status) via Short Physical Performance Battery test....
Cancer and chemotherapy induce a severe loss of muscle mass (known as cachexia), which negatively impact cancer treatment patient survival. The aim the present study was to investigate whether cannabidiol (CBD) administration may potentially antagonize effects cisplatin in inducing atrophy, using model myotubes culture. Cisplatin resulted reduction myotube diameter (15.7 ± 0.3 vs. 22.2 0.5 µm,
Objectives/Hypothesis PENTOCLO treatment, associating pentoxifylline, tocopherol, and clodronate, resolves radiation‐induced fibrosis. The main aim of the present study was to prospectively assess efficacy in mandibular osteoradionecrosis (ORN). Study Design Prospective cohort study. Methods Twenty‐seven patients with ORN were included Pentoclauvergne between January 2014 February 2016. After an initial 28‐day phase antibiotic, antifungal, corticosteroid therapy, they received association...
Abstract Background The rate of toxic deaths related to induction chemotherapy in the treatment locally advanced head and neck cancers is unacceptable calls into question this therapeutic strategy, which however highly effective terms speed response. purpose study was investigate predictive factors toxicity with docetaxel, cisplatin, 5-fluorouracil (TPF) (LAHNC). Methods Between June 2009 December 2017, 113 patients treated consecutively TPF were included retrospectively. Patients receiving...
ABSTRACT Background The purpose of this study was to evaluate the contribution laryngeal intraoperative nerve monitoring (IONM) during thyroidectomy in predicting postoperative mobility. Methods Between 2009 and 2012, 127 patients underwent thyroidectomy, which 216 recurrent nerves were stimulated with suprathreshold stimulations. Laryngeal mobility examined through direct laryngoscopy. Statistical analysis performed determine specificity, sensitivity, negative predictive value (NPV),...
To determine the importance of nutritional status, social and inflammatory status in prognosis head neck cancer.Single-center retrospective study prospectively collected data.Tertiary referral center.Ninety-two consecutive patients newly diagnosed for cancer upper aerodigestive tract without metastases were assessed at time diagnosis several prognostic factors. Nutritional was by risk index, EPICES score, systemic response index. The primary endpoint overall survival.In multivariable...
The aim of our study was to identify clinical criteria for optimizing rehabilitation patients with unilateral deafness using the Baha device. We made a retrospective 102 requesting auditory over period 5 years. All subjects underwent series stereo audiometric tests, and without worn on headband, were then referred hearing care specialist real life trial 15 days. Glasgow Health Status Inventory (GHSI) questionnaire administered. Patients refusing implantation retrospectively submitted...