A5083229086- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Nerve Injury and Rehabilitation
- Sports injuries and prevention
- Trauma Management and Diagnosis
- Orthopedic Surgery and Rehabilitation
- Musculoskeletal pain and rehabilitation
- Bone fractures and treatments
- Multiple Sclerosis Research Studies
- Foot and Ankle Surgery
- Hip disorders and treatments
- Cerebral Palsy and Movement Disorders
- Tendon Structure and Treatment
- Muscle activation and electromyography studies
- Spinal Cord Injury Research
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Autoimmune and Inflammatory Disorders Research
- Medical research and treatments
- Total Knee Arthroplasty Outcomes
- Peripheral Nerve Disorders
- Cardiac Valve Diseases and Treatments
- Rheumatoid Arthritis Research and Therapies
- Neuroinflammation and Neurodegeneration Mechanisms
- Inhalation and Respiratory Drug Delivery
Odense University Hospital
2013-2024
University of Southern Denmark
2009-2024
Sygehus Sønderjylland
2021-2024
Region of Southern Denmark
2022
Orthopaedic Research
2020
Akershus University Hospital
2018
Kirkelig Pedagogisk Senter
2014
Rigshospitalet
2013
Aarhus University Hospital
1988-2001
Regional Hospital Randers
1995
To determine quantitative exposure-response relations between work with highly elevated arms and supraspinatus tendinitis, shoulder pain disability, without disability.A cross sectional study was conducted in a historical cohort of 1886 males from three occupational groups. Exposure measurements were performed for four consecutive working days random sample 72 currently employed subjects. Individual histories obtained by questionnaire register data. Health status ascertained physical...
Abstract Preclinical and clinical proof-of-concept studies have suggested the effectiveness of pharmacological modulation inflammatory cytokines in ischemic stroke. Experimental evidence shows that targeting tumor necrosis factor (TNF) interleukin (IL)-1 holds promise, these are considered prime targets development new stroke therapies. So far, however, information on cellular expression TNF IL-1 human brain is sparse. We studied 14 cases post-mortem stroke, representing 21 specimens...
Background: Ischemic stroke causes increased blood-brain barrier permeability and release of markers axonal damage inflammation. To investigate diagnostic prognostic roles neurofilament light chain (NF-L), we assessed levels NF-L, S100B, interleukin-6 (IL-6), E-selectin, vascular endothelial growth factor-A (VEGF-A), cell adhesion molecule-1 (VCAM-1), intercellular (ICAM-1) in patients with acute ischemic or transient attack (TIA) healthy controls. Methods: We studied (NF) expression 2 cases...
To determine whether work performed with the arms in a highly elevated position is associated alterations rotator cuff tendons as assessed by magnetic resonance imaging (MRI).A cross-sectional study was historical cohort of male machinists, car mechanics, and house painters. The participants were right-handed, ages 40-50 years, had been employed their trades for not less than 10 years. Seventy-one percent invited subjects participated (136 192). Lifetime upper arm elevation direct...
ABSTRACT From 1983 to 1988, 42 shoulder arthroplasties were performed on comminuted acute or chronic proximal humeral fractures. Patients categorized according the postfracture operative delay; there 15 fourpart fractures, with median post-fracture delay of 13 days (range: 7 21), and 27 including 11 four-part 9 three-part two-part 14 months 4 72). Follow up was approximately 2 years in both groups 1 5). AH patients evaluated a modified Neer score-system classified into four groups. Pain...
Measurement of electrical impedance can discriminate between tissues different properties. A measurement system with adequate spatial resolution focused on a volume around the tip needle or other invasive clinical equipment be used to determine in which type tissue is positioned. We have measured sensitivity zone electrode an active area 0.3 mm(2), and spectra porcine vivo. Small data will influenced by polarization (EPI) at low frequencies. To refine existing methods for guidance higher...
Study Design A prospective cohort study nested in a randomized controlled trial. Objectives To determine and compare responsiveness minimal clinically important change of the modified Constant score (CS) Oxford Shoulder Score (OSS). Background The OSS CS are commonly used to assess shoulder outcomes. However, few studies have evaluated measurement properties terms change. Methods included 126 patients who reported having difficulty returning usual activities 8 12 weeks after arthroscopic...
Three-dimensional finite element analysis is one of the best ways to assess stress and strain distributions in complex bone structures. However, accuracy results may be achieved only when accurate input information given. A semi-automated method generate a (FE) model using data retrieved from computed tomography (CT) was developed. Due its irregular shape, glenoid part left embalmed scapula chosen as working material. CT were standard clinical scanner (Siemens Somatom Plus 2, Siemens AG,...
Rheumatoid arthritis of the shoulder is a progressive and destructive joint disease, similar to in other joints, progression disease unpredictable may stop at any stage involvement. Between 1983 1996, more than 500 prostheses were implanted patients authors' institution. Total replacement yields satisfactory short long term results even with severely destructed joints. Pain relief reliable significant as reported studies. In most functional result good or acceptable. Although range motion...
There is an important gap in knowledge about the effectiveness of nonoperative treatment (exercise) for patients with traumatic primary and recurrent anterior shoulder dislocations (ASDs).The purpose this study was to assess efficacy safety physical therapist-supervised, instability neuromuscular exercise (SINEX) versus self-managed, home-based, standard care (HOMEX) ASDs. The hypothesis that SINEX would have a larger effect fewer adverse events compared HOMEX.Randomized controlled trial;...
BackgroundRotator cuff (RC) disorders involve a spectrum of shoulder conditions from early tendinopathy to full-thickness tears leading impaired function and pain. The pathology RC disorder is, nonetheless, still largely unknown. Our hypothesis is that supraspinatus (SS) tendon tear leads sustained inflammatory changes the SS muscle along with fatty infiltration degeneration, which are threshold markers for poor function. aim this study was determine extent inflammation in conjunction lipid...
ABSTRACT: Fourteen hip arthroscopies between January 1985 and May 1988 were reviewed. Included ten women four men with an age ranging from 12 to 76 years. Indications avascular necrosis; loose bodies; osteoarthrosis, arthritis, or pain; snapping hip. The diagnosis was verified in five cases, including arthroscopic removal of a body one resection plica bridging the space femoral head acetabular roof two patients. rejected three cases. In no pathologic changes found. One arthroscopy...
Although tumor necrosis factor (TNF) inhibitors are used to treat chronic inflammatory diseases, there is little information about how long-term inhibition of TNF affects the homeostatic functions that maintains in intact CNS. To assess whether developmental deficiency causes alterations naïve CNS, we estimated number proliferating cells, microglia, and neurons developing neocortex E13.5, P7 adult knock out (TNF−/−) mice wildtype (WT) littermates. We also measured changes gene protein...
Rotator cuff (RC) tendon tear leads to impaired shoulder function and pain. The supraspinatus (SS) is most often affected, but the biological response of SS muscle largely unknown. This study aimed investigate time-dependent inflammation, degeneration, fatty infiltration, regeneration in experimental conditions.Forty-five C57BL/6 mice were subjected allowed recover for 1, 3, 5, 7, 14, or 28 days. extent damage was examined using histologic, flow cytometric, proteomic, chemiluminescence...
A unilateral patellar malalignment was induced in 20 young and mature rabbits by lateral displacement of the tibial tuberosity, other knee serving as osteotomized situ control.At 6 weeks, all knees appeared macroscopically normal, but histologically definite cartilage degeneration found on experimental side. At 3 months, macroscopic changes occurred 5 10 rabbits, histologic knees, most pronounced animals, particularly joint facets submitted to high pressure.This model produces resembling...
Orthopaedic surgeons disagree considerably when classifying fractures of the proximal humerus. However, clinical implications low observer agreement remain unclear. The purpose study was to compare on Neer classification with treatment recommendations.We conducted a multi-centre observer-study. Five experienced shoulder independently assessed consecutive series 193 radiographs at two occasions three months apart. All pairs were classified according Neer. Subsequently, observers asked...
Background Physiotherapy with exercises is generally recommended in the treatment of patients subacromial impingement syndrome (SIS). Objective We aimed to investigate use physiotherapy SIS Danish hospital settings as part initial non-surgical and after SIS-related surgery evaluate which extent sex, socio-demographic clinical factors predict physiotherapy. Methods Using national health registers, we identified 57,311 who had a first contact diagnosis ICD-10, groups M75.1–75.9, 1 July 2007 30...
Patients with non-operated traumatic primary anterior shoulder dislocation (PASD) are assumed to have less impairment than patients recurrent dislocations (RASD). This may impact treatment decision strategy. The aim was study whether PASD those RASD. In a cross-sectional baseline data from and RASD in randomised controlled trial of non-operative exercise were used. Shoulder function self-reported (Western Ontario Instability (WOSI), Tampa Scale Kinesiophobia (TSK), General Health...