A5101876174- Lower Extremity Biomechanics and Pathologies
- Hip disorders and treatments
- Orthopaedic implants and arthroplasty
- Sports injuries and prevention
- Knee injuries and reconstruction techniques
- Antibiotics Pharmacokinetics and Efficacy
- Radiation Dose and Imaging
- Pharmacological Effects and Assays
- Analytical Methods in Pharmaceuticals
- Osteoarthritis Treatment and Mechanisms
- Shoulder Injury and Treatment
- Bone and Joint Diseases
- Hip and Femur Fractures
- Foot and Ankle Surgery
- Attention Deficit Hyperactivity Disorder
- Cervical and Thoracic Myelopathy
- Cardiac electrophysiology and arrhythmias
- Receptor Mechanisms and Signaling
- Smoking Behavior and Cessation
- Child Nutrition and Feeding Issues
- T-cell and Retrovirus Studies
- Neurotransmitter Receptor Influence on Behavior
- Synthesis and Biological Evaluation
- Cardiovascular Disease and Adiposity
- Eicosanoids and Hypertension Pharmacology
Sunnybrook Health Science Centre
2022
Health Sciences Centre
2022
Robert Jones and Agnes Hunt Orthopaedic Hospital
2018-2020
Northwick Park Hospital
2012-2013
University of Glasgow
2010-2012
Wayne State University
2009
University of Newcastle Australia
1999
Addenbrooke's Hospital
1994
University of Cambridge
1994
London School of Hygiene & Tropical Medicine
1987-1988
Hip arthroscopy remains a useful surgical intervention for labral injuries. The literature has predominantly focused on structural and vascular considerations of the hip joint, with few studies examining neurohistology surrounding periarticular tissues. We mapped identified neural anatomy, to identify presence sensory nerve fibres mechanoreceptors within joint. Eight human cadaveric hips were dissected into total ten specimens per hip. Histological staining was used structures taken from...
BACKGROUND Serotonin may contract human large coronary arteries through two 5-hydroxytryptamine (5-HT) receptors, 5-HT1-like and 5-HT2. These receptors resemble both cloned 5-HT1D receptor subtypes, alpha 5-HT 1D beta. Although these subtypes have similar pharmacology, beta appear to lower affinity for ketanserin than receptors. We assessed the relative participation of 5-HT2 attempted identify whether vasoconstrictor are or METHODS AND RESULTS Epicardial were dissected from hearts 29...
A total of 22,552 workers employed by the Atomic Weapons Establishment between 1951 and 1982 were followed up for an average 18.6 years. Of 3115 who died, 865 (28%) died cancer. Mortality was 23% lower than national all causes death 18% These low rates consistent with findings in other workforces nuclear industry reflect, at least part, selection healthy people to work disproportionate recruitment from higher social classes. At some time during their employment 9389 (42%) monitored exposure...
Trochlear dysplasia is a significant risk factor for patellofemoral instability. The Dejour classification currently considered the standard classifying trochlear dysplasia, but numerous studies have reported poor reliability on both plain radiography and MRI. severity of important to establish in order guide surgical management. We developed an MRI-specific system assess Oswestry-Bristol Classification (OBC). This four-part comprising normal, mild, moderate, severe represent shallow, flat,...
Background Certain first‐ and second‐generation H 1 ‐receptor antagonists are associated with prolongation of the corrected QT interval (QTc) and, in rare instances, ventricular dysrhythmias, including torsades de pointes tachycardia. Objective To assess effect fexofenadine HCl, a new non‐sedating antihistamine, on QTc. Methods Dose‐tolerance, safety, drug‐interaction studies healthy volunteers; clinical efficacy seasonal allergic rhinitis patients were conducted. Twelve‐lead ECG data...
The United Kingdom Atomic Energy Authority mortality study was designed to investigate the relation between exposure ionising radiation and among authority9s employees. present paper describes some of problems encountered in assessing occupational low dose examines whether study9s conclusions about could be affected by methods used. covered years 1946 1979 during which time frequency with personal film dosimeters were issued changed from weekly monthly, threshold level below measurements not...
Chronic groin pain in young athletic patients poses a difficult diagnostic and therapeutic challenge, especially with such wide variety of potential causes. Sports hernias were first described the early 1980s, are an increasingly recognised cause chronic pain. Injury to number high profile athletes has raised public awareness this condition. Typically occurring males, sports usually present insidious onset exercise-related pain. It is often disabling results cessation participation...
Autologous chondrocyte implantation (ACI) has been used to treat cartilage defects for >20 years, with promising clinical outcomes. Here, we report two first-in-man cases (patient A and B) treated combined autologous bone marrow mesenchymal stromal cell (CACAMI), 8-year follow up. Two patients International Cartilage Repair Society (ICRS) grade III–IV lesions underwent a co-implantation of chondrocytes marrow-derived cells (BM-MSCs) between February 2008 October 2009. In brief, BM-MSCs...
Background Data gathered from previous studies has demonstrated the efficacy and safety of lamotrigine in adult psychiatric population; however, it not been well studied children adolescents with mood disorders (Watanabe & Hongo, 2017). Objective The objective this study is to understand patients’ perspective Lamotrigine when prescribed for disorders. Methods A proposal was approved by University Missouri-Columbia Internal Review Board conduct study. To answer a questionnaire, 20...
We present a case of severe heterotopic ossification following primary total knee replacement, which was complicated by intraoperative anaphylactic reaction, and the successful treatment revision to rotating platform hinged implant, 32 months index procedure.
Clusters of disease are common and occur in the workplace general community. They often arouse considerable concern among population. Investigations have sometimes lead to exciting new knowledge, but investigation clusters is difficult unrewarding, especially for community clusters. In workplace, investigations more likely find associations even causes, still many remain enigmatic. Despite this, there reasons investigating clusters, including allaying identifying uncontrolled exposures. A...
Marlboro is 50 years old—and still killing its customers