High altitude and hypoxic preconditioning have cardioprotective effects by increasing coronary vascularity, reducing post-ischemic injury, improving cardiac function. Our purpose was to examine if intermittent hypoxia treatment has any restoring related the possible role of HIF-1/VEGF pathway on diabetic cardiomyopathy.Wistar Albino male rats (n=34) were divided into four groups: control (C), (IH), diabetes mellitus (DM), plus (DM+IH). Following a streptozotocin (STZ) injection (50 mg/kg,...

Background/Aims. Boron is used in manufacturing processes and numerous consumer products. Clarification of boron toxicity important because industrial exposure to boron-containing compounds. The aim this study was observe effects subacute boric acid administration on rat kidney tissue. Materials Methods. A total 96 male albino Sprague-Dawley rats were study. Seventy-two selected for the experimental group 24 constituted control group. Experimental divided into three groups different doses...

Background:In recent years, pimecrolimus 1% cream has been demonstrated to reduce symptoms of atopic dermatitis in patients when applied topically.Material/Methods:In our study we compared the therapeutic effects local hydrocortisone, and a control group mouse model with external ear canals. Atopic was created by application Dinitrochlorobenzene canals mice. The development detected clinical observation score determination total serum IgE levels. Pimecrolimus hydrocortisone were topically...

Pregnant endometrial stroma, an immunologically privileged site in the female reproductive system, is enriched by decidual and natural killer (NK) cells. Since cellular microenvironment early pregnancy from tissues of normal miscarriage cases has gained importance, with special emphasis on cell-to-cell contacts, we aimed to document plastic structure milieu decidua.Endometrial biopsies were obtained women after legal curettage or who had been treated miscarriage. Samples analysed a light...

In nerve injuries, if it is not possible to reinnervate muscle by using neurorrhaphy and grafting technique, reinnervation should be provided the use of neuroization-directly implanting motor into muscle. A comparative study three techniques neurotization presented in rabbits.

Three-dimensional defects have been reconstructed with carved and remodeled frameworks wrapped within vascular carriers wide use in ear nose reconstruction. The main problem thick coverings is masking of the fine details frameworks. Other problems are insufficient blood supply, infection, exposure implant. If sufficient penetration can be established without any change size shape implant, it will possible to cover a thin skin graft improve aesthetic results. In this study we planned...

Abstract Neurorraphy, conventional nerve grafting technique, and artificial conduits are not enough for repair in severe injuries of peripheral nerves, especially when there is separation motor from muscle tissue. In these injuries, reinnervation indicated neurotization. The distal end a divided into fascicles implanted the aneural zone target It known how deeply should be A comparative study superficial deep implantation separated tissue presented gastrocnemius rabbits. this experimental...

To investigate the pathophysiology of punctal stenosis based on histopathological features, and to assess correlation between findings treatment outcomes in primary stenosis.A total 43 eyes 34 consecutive patients with were included this prospective study. Punctum specimens obtained by rectangular three-snip punctoplasty (TSP) examined multilayered structure epithelium subepithelial histopathology. The was evaluated.A 61.8% female had an average age 62.4 (41-81) years. Based examination, all...

There have been plenty of reconstruction methods for ear amputation, and replantation preserves its importance. In situations where is not feasible, various were proposed. We indicate an alternative technique the amputation without indication. The method replacing a vascular structure into tunnel formed on posterior side amputated was used instead cartilage area that described in literature prefabrication. dorsal fascial flaps which prepared from back 10 New Zealand rabbits placed ear. 2...

Clinical and experimental studies have been conducted to improve the survival of venous flaps. As a result these studies, although various mechanisms were raised, none obtained satisfactory information. Venous stasis, resultant thrombosis, is factor that decreases In this study, we evaluated effects two antiinflammatory agents, etodolac etofenamate, on unipedicled 35 male New Zealand white rabbits (3,500-4,000 g) (70 ears) used. Perichondrocutaneous flaps, 3 x 4.5 cm in size, designed...

To demonstrate progression of acute and chronic endocrinopathies in a kaolin-induced hydrocephalus model using light microscopy.Adult male Sprague-Dawley rats (n = 48) were divided into six groups. Hydrocephalus was induced by intracisternal injection kaolin solution the groups, whereas an identical volume sterile saline injected sham groups.Somatotropic cell concentrations lower groups compared with their controls, but there no difference somatotropic concentration between Corticotropic...

This study aimed to evaluate the effect of using an inferior or superior conjunctival autograft in primary pterygium surgery on postoperative ocular surface.

Purpose: The purpose of this study was to evaluate the cytologic analysis aqueous humor (AH) eyes with Fuchs uveitis (FU) and idiopathic anterior (IAU). Methods: AH 25 uveitic (12 FU 13 IAU) were evaluated cytologically. samples chamber taken before cataract surgery. Aqueous fluid by applying a Giemsa stain. Results: 12 patients IAU included in study. In AH, number lymphocytes similar (the lymphocytes: min:1 max:7). acellular amorphous structures detected FU, same finding not observed IAU....

Memelilerde deri uzerinde yanik, kesi gibi herhangi bir hasar sonrasi olusan yara rejenerasyonla degil fibroproliferatif yanitla, yani skar olusumuyla onarilir. Oysa kozmetik gorunumu bozmakla kalmaz, cogu zaman ciddi tibbi sorunlara da yol acar. Ustelik skarla iyilesen deri, saglam deriye gore gerilime karsi daha zayiftir. Bu calismada temiz insizyonel yaralarda iyilesmenin onlenebilmesi acisindan once anti-fibrotik etkileri de pek cok calismayla gosterilmis olan pentoksifilinin (PTX)...