A5047864188- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Tracheal and airway disorders
- Respiratory and Cough-Related Research
- Diversity and Career in Medicine
- Esophageal and GI Pathology
- Head and Neck Cancer Studies
- Gastroesophageal reflux and treatments
- Speech Recognition and Synthesis
- Airway Management and Intubation Techniques
- Healthcare Systems and Technology
- Phonetics and Phonology Research
- Asthma and respiratory diseases
- Obstructive Sleep Apnea Research
- Stuttering Research and Treatment
- Cleft Lip and Palate Research
- Foreign Body Medical Cases
- Circadian rhythm and melatonin
- Head and Neck Anomalies
- Occupational health in dentistry
- Pathogenesis and Treatment of Hiccups
- Hemostasis and retained surgical items
- Trypanosoma species research and implications
- Natural Antidiabetic Agents Studies
- Nigella sativa pharmacological applications
Loma Linda University
2014-2025
All India Institute of Medical Sciences, Nagpur
2025
Loma Linda University Health Care
2021-2024
Loma Linda University Medical Center
2015-2024
Temple University
2024
Harvard University
2024
American Academy of Otolaryngology — Head and Neck Surgery
2024
General Hospital Ernakulam
2023
National Institute on Aging
2021-2022
National Institutes of Health
2021-2022
Abstract Cancer incidence increases with age and is a leading cause of death. Caloric restriction (CR) confers benefits on health survival delays cancer. However, due to CR’s stringency, dietary alternatives offering the same cancer protection have become increasingly attractive. Short cycles plant-based diet designed mimic fasting (FMD) are protective against tumorigenesis without chronic calories. Yet, it unclear whether time, level restriction, or nutrient composition primary driver...
An increasing number of laryngeal procedures are performed in the office. However, little is known about how well these tolerated and what factors determine success or failure.Prospectively collected patient physician surveys from five surgeons at two institutions describe tolerance awake, in-office (AIOLPs).There were 154 a 6-month period, including vocal fold injection (VFI) (72%), laser treatment (19%), transnasal esophagoscopy (3%). Average duration procedure was 13 ± 8 minutes.Patients...
Injection laryngoplasty (IL) continues to evolve as new indications, techniques, approaches, and injection materials are developed. Although historically performed under local or general anesthesia in the operating room suite, IL is now increasingly being an office-based setting. This report presents results of a reimbursement analysis comparing versus operative IL.The objective this study was compare with performing same procedure room.The authors conducted outcome through retrospective...
An aging population experiences an increase in age-related problems, such as presbyphonia. The causes of pathologic presbyphonia are incompletely understood.To determine what distinguishes from presbylaryngis.This was a cohort study at outpatient otolaryngology subspecialty clinic tertiary academic referral center. Participants were consecutive consenting adults older than 74 years without laryngeal abnormalities who visited the participants or companions. Patient questionnaires,...
Purpose: Chronic refractory cough (CRC), defined as lasting over 8 weeks despite medical intervention, is a prevalent condition with number of associated comorbidities. Cough suppression therapy (CST) has been demonstrated to be promising avenue for treating CRC by improving airway control and coordination. However, little known about the effects CST in patients diagnosed comorbid oropharyngeal dysphagia (DYS) large subset both conditions. The purpose this study was determine if affects...
We studied the effect of transforming growth factor (TGF)-beta on immortalized human vocal fold fibroblasts.Normal fibroblasts were subjected to sequential lentiviral transduction with genes for telomerase (hTERT) and SV40 large T antigen in order produce an "immortalized" cell line normal phenotype. After confirmation fibroblast transfection, these cells, referred as HVOX, treated various concentrations exogenous TGF-beta1 assayed collagen secretion, migration, proliferation. In addition,...
ABSTRACT Introduction : Nimodipine has been shown to be beneficial for recovery from acute vocal fold paralysis (AVFP) in an animal model. Methods prospective, open‐label trial of patients with AVFP was performed using nimodipine. Consecutive were evaluated and offered nimodipine therapy. Results Fifty‐three considered treatment Thirteen did not qualify inclusion, 5 lost follow‐up, 7 had side effects requiring cessation treatment. Thus 28 (30 paralyzed folds) analyzed. Eighteen the folds...
This study examines the relationship between chronic cough and vagal hypersensitivity by measuring baseline esophageal motility, with interest in upper sphincter (UES).
To examine aspects of litigation involving iatrogenic dysphonia and injury to the recurrent laryngeal nerve in adult population.Legal database review.Medicolegal judicial system.Jury verdicts settlement reports listing voice impairment or dysfunction as a primary patients were identified Westlaw Database. Reports examined for plaintiff demographics, defendant specialty, procedure performed, rates settlements verdicts, monetary awards, symptoms, common allegations.A total 123 jury verdict...
OBJECTIVE To investigate hepatocyte growth factor (HGF) primed fibroblasts and decorin application on skin vocal fold in vitro vivo rabbit scar model. STUDY DESIGN AND SETTING: Vocal underwent five treatment conditions: control, epidermal factor, HGF, both alone. Hyaluronic acid collagen enzyme‐linked immunosorbent assays were performed. In vivo, 12 rabbits unilateral stripping. Injured folds then injected with fibroblasts, HGF‐primed decorin, or decorin. Outcomes included histologic lamina...
✓ Vagus nerve stimulation for treatment of epilepsy is considered safe; reports severe complications are rare. The authors report on two developmentally disabled patients who experienced vocal cord paralysis weeks after placement a vagus stimulator. In both cases, traction injury to the resulting in was caused by rotation pulse generator at subclavicular pocket patient. Traumatic tampering with their device has never been reported and may be analogous similar phenomenon cardiac pacemakers...
Objectives/Hypothesis In‐office laryngology procedures are important in the treatment of voice and swallowing disorders. Patient tolerance determines which can be performed without sedation or formal anesthesia. This study examines pain perception during after in‐office vocal fold injection augmentation. Study Design Prospective cohort study. Methods Patients scheduled for office‐based augmentation were prospectively enrolled at an academic center. The short‐form McGill Pain Questionnaire...
Objectives: Vocal fold injury can be irreversible, leading to vocal scarring, with permanent functional effects and no optimal treatment. A porcine model of scarring was used test decorin primed fibroblasts in vitro using a cell migration assay immunoblotting, by measurements larynges excised folds. Methods: In vitro: primary pig (PVFFs) were subjected assays (scratch) treated 20 μg/mL, hepatocyte growth factor (HGF) 200 ng/mL, epidermal (EGF) 1 nM, or transforming factor-β1 10 ng/mL. Cells...
Introduction Quantitative measurement and analysis of glottic abduction is used to assess laryngeal function success interventions; however, the consistency over time has not been established. This study assesses measurements across visits in healthy patients anatomic factors impacting these measurements. Methods Review with two sequential flexible stroboscopic exams seven months from 2019–2022. Images maximal were captured uploaded into measured ImageJ. Cadaver heads impact visualization...
Objectives//Hypothesis To determine changes in voice severity when treating chronic cough refractory to medical treatment with suppression therapy (CST) patients and complaints. Chronic has been reported be frequently co‐occurs disorders. The possible effects of CST on self‐assessed disorders have not demonstrated. Study Design Retrospective analysis the disorder both Methods Forty‐three adult primary complaint underwent pre‐ post‐treatment diagnostic examinations, completed Voice Handicap...