A5101973736- Advanced Materials and Mechanics
- Advanced Sensor and Energy Harvesting Materials
- Hydrogels: synthesis, properties, applications
- Electrospun Nanofibers in Biomedical Applications
- Micro and Nano Robotics
- RNA Research and Splicing
- Modular Robots and Swarm Intelligence
- Cancer-related molecular mechanisms research
- Tissue Engineering and Regenerative Medicine
- Advanced Measurement and Detection Methods
- Infrared Target Detection Methodologies
- Polymer composites and self-healing
- DNA Repair Mechanisms
- Organ Transplantation Techniques and Outcomes
- Dielectric materials and actuators
- Liver physiology and pathology
- Circular RNAs in diseases
- Soft Robotics and Applications
- 3D Printing in Biomedical Research
- Glioma Diagnosis and Treatment
- Hydraulic Fracturing and Reservoir Analysis
- Robotic Locomotion and Control
- Acute Myeloid Leukemia Research
- Acute Lymphoblastic Leukemia research
- Elasticity and Material Modeling
Zhejiang University
2016-2025
Nanjing University of Aeronautics and Astronautics
2025
Yangtze University
2016-2025
Key Laboratory of Drilling and Production Engineering for Oil and Gas, Hubei Province
2025
Zhengzhou University of Light Industry
2025
Army Medical University
2017-2023
Affiliated Hospital of Southwest Medical University
2021-2023
Denver School of Nursing
2021-2022
National Center on Birth Defects and Developmental Disabilities
2022
Xiamen University
2016-2022
Soft robots driven by stimuli-responsive materials have unique advantages over conventional rigid robots, especially in their high adaptability for field exploration and seamless interaction with humans. The grand challenge lies achieving self-powered soft mobility, environmental tolerance, long endurance. We are able to advance a electronic fish fully integrated onboard system power remote control. Without any motor, the is solely electroactive structure made of dielectric elastomer...
Abstract 3D printing technology has been widely explored for the rapid design and fabrication of hydrogels, as required by complicated soft structures devices. Here, a new method is presented based on rheology modifier Carbomer direct ink writing various functional hydrogels. shown to be highly efficient in providing ideal rheological behaviors multifunctional hydrogel inks, including double network magnetic temperature‐sensitive biogels, with low dosage (at least 0.5% w/v) recorded. Besides...
As one of the most promising drug delivery carriers, hydrogels have received considerable attention in recent years. Many previous efforts focused on diffusion-controlled release, which allows to load and release drugs vitro and/or vivo. However, it hardly applies lipophilic due their poor compatibility with hydrogels. Herein, we propose a novel method for based dual pH-responsive hydrogel actuator. Specifically, is encapsulated can be released by pH-controlled capsule switch. Inspired...
Hydrogen bond engineering is widely exploited to impart stretchability, toughness, and self-healing capability hydrogels. However, the enhancement effect of conventional hydrogen bonds severely limited by their weak interaction strength. In nature, some organisms tolerate extreme conditions due strong interactions induced trehalose. Here, we report a trehalose network-repairing strategy achieved covalent-like bonding improve hydrogels' mechanical properties while simultaneously enabling them...
Abstract Outstanding overall mechanical properties are essential for the successful utilization of hydrogels in advanced applications such as human-machine interfaces and soft robotics. However, conventional suffer from fracture toughness-stiffness conflict fatigue threshold-stiffness conflict, limiting their applicability. Simultaneously enhancing toughness, threshold, stiffness hydrogels, especially within a homogeneous single network structure, has proven to be formidable challenge. In...
Hydrogels consist of cross-linked polymers that are highly swollen with water. Water evaporation or freezing during temperature changes may lead to stiff and brittle hydrogels. We introduce a strategy called “hydro-locking,” which involves immobilizing the water molecules within polymer network hydrogel. This is accomplished by establishing robust connections between using sulfuric acid. A sacrificial introduced shield prime from collapsing. Under hydro-locking mode, an...
Transcription factors play important roles in lymphopoiesis. We have previously demonstrated that Bcl11a is essential for normal lymphocyte development the mouse embryo. report here that, adult mouse, expressed most hematopoietic cells and highly enriched B cells, early T cell progenitors, common lymphoid progenitors (CLPs), stem (HSCs). In deletion causes apoptosis CLPs completely abolishes potential of HSCs to B, T, NK cells. Myeloid development, contrast, not obviously affected by loss...
Typical hydrogels undergo slow and continuous shape change. Inspired by the Venus Flytrap, current work presents a hydrogel assembly that can reversibly non-continuous rapid snapping change due to bi-stable structure of assembly. In particular, reversible goes beyond Flytrap is not known in literature.
Magnetic hydrogels have promising applications in flexible electronics, biomedical devices, and soft robotics. However, most existing magnetic are fragile suffer insufficient response. In this paper, we present a new approach to fabricate strong, tough, adhesive hydrogel with nontoxic polyacrylamide (PAAm) as the matrix functional additive [3-(trimethoxysilyl)propyl methacrylate coated Fe3O4] inclusions. This not only offers relatively high modulus toughness compared pure but also responds...
3D printing of hydrogels finds widespread applications in biomedicine and engineering. Artificial cartilages heart valves, tissue regeneration soft robots, require high mechanical performance complex structures. Although many tough have been developed, complicated synthesis processes hinder their fabrication printing. Here, a strategy is proposed to formulate hydrogel inks, which can be printed into various strong particle-based double-network (P-DN) arbitrary shapes without any rheological...
Soft materials fail by crack propagation under external loads. While fracture toughness of a soft material can be enhanced orders magnitude, its fatigue threshold remains insusceptible. In this work, we demonstrate tip softening (CTS) concept to simultaneously improve the and single polymeric network. Polyacrylamide hydrogels have been selected as model material. The polymer network is cured two kinds crosslinkers: normal crosslinker light-degradable crosslinker. We characterize pristine...
Abstract Recently, hydrogels with coloration have attracted researchers from various fields, such as camouflage, anti‐counterfeiting, and soft display. However, existing thermochromic are limited by their weak color display performance insufficient sensitivity. Here proposed is a new kind of hydrogel which possesses bright colors, fast response time, reliable results across long lifespan. This prepared embedding temperature‐responsive microcapsules containing three components: developing...
Abstract High aggressiveness is a hallmark of glioblastoma and predicts poor prognosis patients with glioblastoma. The expression level sortilin has been preliminarily reported to be elevated in high-grade glioma; however, the potential significance progression not elucidated. In this study, we investigated oncogenic effect Increased levels were noted mesenchymal subtype highly aggressive subtypes tissues cell lines. addition, high predicted prognoses Sortilin knockdown or inhibition AF38469...
Abstract The invasion ability of glioblastoma (GBM) causes tumor cells to infiltrate the surrounding brain parenchyma and leads poor outcomes. Transient receptor potential vanilloid 4 (TRPV4) exhibits a remarkable role in cancer cell motility, but contribution TRPV4 metastasis is not fully understood. Here, we reported that expression was significantly elevated malignant glioma compared normal low-grade glioma, negatively correlated with prognosis patients. Functionally, stimulation promoted...