- Reproductive System and Pregnancy
- Endometriosis Research and Treatment
- Ovarian function and disorders
- Reproductive Biology and Fertility
- Gynecological conditions and treatments
- Uterine Myomas and Treatments
- Pregnancy and preeclampsia studies
- Reproductive Physiology in Livestock
- Sperm and Testicular Function
- Ectopic Pregnancy Diagnosis and Management
- Pregnancy and Medication Impact
- Ovarian cancer diagnosis and treatment
- Cytokine Signaling Pathways and Interactions
- Vitamin D Research Studies
- Cancer-related molecular mechanisms research
- Cell Adhesion Molecules Research
- Hypothalamic control of reproductive hormones
- Endometrial and Cervical Cancer Treatments
- Bioactive Compounds and Antitumor Agents
- Estrogen and related hormone effects
- Growth Hormone and Insulin-like Growth Factors
- Assisted Reproductive Technology and Twin Pregnancy
- Lipid metabolism and disorders
- Synthesis and Reactions of Organic Compounds
- Fetal and Pediatric Neurological Disorders
First Affiliated Hospital of GuangXi Medical University
2016-2025
Guangxi Medical University
2016-2025
Guilin Medical University
2024-2025
Yangzhou University
2025
State Key Laboratory of Respiratory Disease
2021
Guangzhou Medical University
2009-2021
Sun Yat-sen University
2021
Hunan Mawangdui Hospital
2010
Beijing Xuanwu Traditional Chinese Medicine Hospital
2007
Shanghai Jian Qiao University
2005
Endometriosis is a multifactorial disease associated with inflammation. Vitamin D has anti-inflammatory, antiproliferative, anti-oxidative, and immunomodulatory effects. Whether vitamin levels are correlated endometriosis subject of ongoing debate. This study aimed to examine the association between serum levels. From National Health Nutrition Examination Survey, this examined cross-sectional data American women aged 20-54 years from 2001 2006. After adjusting for covariates, multivariable...
The establishment of pregnancy in human necessitates appropriate decidualization stromal cells, which involves steroids regulated periodic transformation endometrial cells during the menstrual cycle. However, potential molecular regulatory mechanism underlying initiation and maintenance humans is yet to be fully elucidated. In this investigation, we document that SOX4 a key regulator by directly regulating FOXO1 expression as revealed whole genomic binding assay RNA sequencing. Besides, our...
To explore the effects of autologous platelet-rich plasma (PRP) intrauterine perfusion on clinical outcomes in recurrent implantation failure (RIF) patients with non-thin endometrium undergoing frozen-thawed embryo transfer (FET), and PRP used at different times before FET outcomes. A total 160 RIF were retrospectively analyzed. Among them, 82 received 24–72 h (PRP group), 78 did not (non-PRP group). In group, 59 underwent 24–48 (≥ 24 to ≤ 48 23 was 48–72 (> 72 The compared, including β-hCG...
This study aimed to compare the clinical pregnancy rates of hysterosalpingography (HSG) with water-based contrast and hysterosalpingo-contrast sonography (HyCoSy) investigate their impact on fertility outcomes in women endometriosis-related infertility. retrospective included 296 infertility, aged 18-39, undergoing HSG or HyCoSy at First Affiliated Hospital Guangxi Medical University (January 2020-June 2022). Propensity score matching was applied balance demographic variables. Clinical were...
Abstract Peripheral blood mononuclear cells (PBMCs) are rich in hematopoietic and mesenchymal stem cells. Platelet-rich plasma (PRP) is various growth factors. PBMCs PRP have been suggested, individually, to restore ovarian function by improving the local microenvironment. The current study investigated effect of granulocyte colony-stimulating factor (G-CSF)-mobilized combined with on restoring rats primary insufficiency (POI). Thirty adult female were randomly subdivided into five groups:...
Abstract Background The oil-soluble contrast medium used in hysterosalpingography has been shown to have a fertility-enhancing effect, but the underlying mechanism is unclear, especially regarding role of window implantation (WOI). This study aimed assess endometrial immunological impact WOI before and after bathing with women recurrent failure (RIF). Methods descriptive involved two medical centers between December 18, 2019, 30, 2020. We included infertile who underwent three or more...
<title>Abstract</title> Decidualization of human endometrial stromal cells (HESCs) is one the critical steps in establishment pregnancy. HESCs decidualization provides a suitable microenvironment for embryo implantation and pregnancy maintenance. Nevertheless, little known about molecular mechanisms underlying decidualization. In this study, we identified HBP1 as key player HESCs. Knockdown significantly reduced mRNA protein expression levels markers IGFBP1 FOXO1. Although PGR showed no...
BACKGROUND:The purpose of our study was to investigate the functional role microRNA-340 (miR-340) in endometrial carcinoma (EC). MATERIAL AND METHODS:Human EC cell line RL 95-2 transfected with miR-340 mimics, inhibitors, or controls. After 48 h transfection, viability determined by 3-(4, 5-dimethyl-2- thiazolyl)-2, 5-diphenyl -2-H-tetrazolium bromide (MTT) assay. The BrdU assay and apoptosis were performed determine effects mimics inhibitors on proliferation apoptosis, respectively....
Problem The aim of this research was to investigate the effects intrauterine perfusion hCG before a frozen‐thawed embryo transfer ( FET ) in women with different implantation failure numbers. Method Study This retrospective analysis patients undergoing who received an injection 1000 IU transfer. groups included their first (A group, n = 26), second (B 122), and three or more failures (C 77). Corresponding control (no infusion) were also included. pregnancy rates compared among these groups....
Endometrial cancer is a type of malignant tumor the female reproductive system. Preserving fertility in endometrial patients currently formidable challenge. Interleukin-24 (IL-24) unique cytokine suppressor gene belonging to IL-10 family. IL-24 has broad-spectrum antitumor activity through different signaling pathways but does not affect normal cells. therapy may provide new method for treatment cancer.Transfection was used transfer. The expression and related pathway proteins tissue...